Chapter 21: Sources of Disease
The fat old man didn't think about it, and shook his head directly, "No, absolutely not, I hate rats the most." Pen Fun Pavilion www.biquge.info"
Ye Zhenzhen asked another question: "Then have you ever found a mouse in a nursing home?"
This time, the fat old man and the thin old man shook their heads together, "This is even more impossible, this nursing home is very well managed, the hardware facilities and sanitary conditions are the best in the city, and rats are impossible." ”
The fat old man added, "I've lived here for many years, and I've never seen a cockroach, let alone a mouse." ”
The thin old man asked, "Zhen Zhen, why do you keep asking about mice? Could it be that the fat old grandson's illness is related to mice?"
Ye Zhenzhen nodded, "Well, it's probably related." ”
"What disease do I have?" asked the fat old man anxiously.
"Grandpa Sun, I suspect it is hemorrhagic fever, but this is just speculation, if you want to confirm the diagnosis, you will need to do laboratory tests. ”
"Hemorrhagic fever?" the fat old man was confused, as if he had never heard of this disease, and asked, "Is it serious?"
"The symptoms of hemorrhagic fever can range from mild to severe, and as long as it is treated promptly, it can be cured, but hemorrhagic fever is very contagious and needs to be isolated and treated. ”
Ye Zhenzhen explained the knowledge of hemorrhagic fever to everyone, and at the same time thought that the fatality rate of hemorrhagic fever is as high as 20%~90%, especially for the elderly and children with poor physical fitness, the fatality rate is higher, and it must be detected early, rested early, and treated early.
Ye Zhenzhen suggested: "Send Grandpa Sun to the nearest infectious disease hospital first, and all those who have been in contact with Grandpa Sun must be observed and treated." ”
"Okay, go to the hospital. The thin old man immediately went into action.
The thin old man called 120 to explain the situation, and also emphasized that it may be hemorrhagic fever, which is an infectious disease, and it is necessary to take precautions.
Ye Zhenzhen listened to the thin old man's phone call and arrangement, as if she had been professionally trained, and a trace of surprise flashed in her heart.
After the thin old man finished the call, he looked at Ye Zhenzhen again and said, "I have already notified the hospital, you are familiar with the CDC, you can call to inform." ”
"Good. ”
Ye Zhenzhen thought about it for a while, and thought that the district CDC had the ability to detect hemorrhagic fever, so she dialed the phone of the district CDC and explained the situation succinctly.
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In the infectious disease hospital closest to the nursing home, the fat old man was arranged in an isolation ward, and medical staff had already come to do the basic treatment, and the thin old man was also examined.
The hospital's infectious disease department also reported the patient's condition in a timely manner, and the fat old man and all the people in the nursing home who had been in contact with the fat old man were examined.
After some examination, the fat old man found hemorrhagic fever antibodies in the serum, and was diagnosed as hemorrhagic fever, while the other contacts were negative and had no infection.
The originally tense atmosphere was also relaxed, and everything in the nursing home returned to normal, but more attention was paid to hygiene and cleaning than usual, and the fat old man began to recover slowly due to the timely discovery, and successfully passed the typical clinical stage five of hemorrhagic fever, the fever period, the hypotensive shock period, the oliguric period, the polyuria period and the recovery period.
More than a week later, the fat old man entered the recovery period, and after two days of observation, he was ready to be discharged from the hospital, during this period, Ye Zhenzhen would come to the hospital to visit every time she got off work, and the thin old man stayed in the hospital every day.
During the visit, Ye Zhenzhen deliberately collected all kinds of specimens from the fat old man's body, including saliva, blood, urine, and even liver ascites collected in the hospital, and brought them back to the laboratory of Nan Zhiqiao of the CDC in China.
In her spare time, Ye Zhenzhen processed the specimen collected from the fat old man, isolated a hantavirus strain, and then sequenced and sequenced the strain, and then compared it with other virus sequences of other Bunyaviridae in the strain sequence library.
After a whole set of virus research, Ye Zhenzhen found that the sequence of the hantavirus strain isolated from the fat old man was the closest homology to the sequence of the hantavirus strain isolated from a natural source of hemorrhagic fever in northeast China, that is, the virus on the fat old man was transmitted from the hemorrhagic fever foci in Northeast China.
Ye Zhenzhen fell into deep thought, and knew from the previous chat with Grandpa Sun that he had never been to the Northeast in the past two years, not even BJ City, so how could he be infected with the hantavirus epidemic in the Northeast?
It's not that Grandpa Sun has been to the Northeast, then it can only be the hantavirus from the Northeast that came to the nursing home in BJ City, but how did this hantavirus come to BJ? Is it a wild mouse through human transportation, or a virus carrier who travels to the Northeast? or other ways that I haven't thought of at the moment......
Ye Zhenzhen frowned slightly, quietly staring at the hantavirus sequence analysis chart on the computer screen in the laboratory, imagining the possible ways of transmission of various viruses in her mind, and suddenly, someone gently patted her shoulder from behind.
Ye Zhenzhen was startled, and suddenly turned around and saw Nan Zhiqiao's smiling face.
Nan Zhiqiao stood behind Ye Zhenzhen, looked at the computer screen in front of Ye Zhenzhen, and asked, "Whose is the sequence analysis diagram of hantavirus?"
"Grandpa Sun's. ”
"Is that the retired cadre of the nursing home?"
"Hmm. Ye Zhenzhen nodded a little dejectedly.
As soon as Nan Zhiqiao saw Ye Zhenzhen's face, she knew that she was in trouble, so she asked with a smile: "Say, what's the problem?" I'll help you analyze it. ”
Ye Zhenzhen's eyes suddenly lit up, and she said all the questions she was thinking about just now.
After hearing this, Nan Zhiqiao thought for a while and said: "The hantavirus isolated from Grandpa Sun has the closest homology to the hantavirus sequence in the Northeast, and it is determined that Grandpa Sun is infected with the hantavirus epidemic strain in the Northeast, but the problem now is that the migration and transmission path of the virus is not clear." ”
Ye Zhenzhen nodded, thinking to herself, she said a lot just now, but Nan Zhiqiao summarized the key point of the problem in one sentence, and she really deserves the title of great god, so she has to learn more......
Ye Zhenzhen asked: "Senior Nan, is there any easy way to quickly judge the migration path of this virus?"
Nan Zhiqiao shook his head, "There is no easy way, however, there is a troublesome but effective way." ”
"How?"
"It is to ask the patient's contact and exposure history, and record the movements of the people and animals in contact with them in recent times, so as to form a three-dimensional relationship map, and there will be discoveries. ”
Ye Zhenzhen thought for a while, "I also asked the people around Grandpa Sun before, and I even did an inspection, but I didn't find anything." ”
"It must be something that has been missed, and it is the most effective way to determine the route of transmission of the pathogen, remembering, especially the strange things that you have been exposed to. ”