After the successful IPO of the driving service company, Juchen earned $3 billion in cash, of which 100 million was donated to Columbia University, and became a trustee of Columbia University, and was promoted to doctoral supervisor.

At the promotion ceremony, he gave a speech and opened up a new direction of research.

The title of the talk was "The Trio of Evolution".

Seeing this topic, the participants thought: the professor really likes the number three.

The well-deserved Internet celebrity scientist was warmly welcomed by hundreds of academic elite attendees, and there were live broadcasts by science and technology media and video websites, and the professor had not given a speech for a long time.

Juchen seems to have been trained in vocal performance arts, and his control of voice and intonation has become more and more proficient, and he finds that his appearance is average, but his voice is still quite attractive after training.

"Evolution. It's relevant to all of us here, because we're beings at the very top of evolution. We must have all wondered how the primordial first life, the so-called Mother of Life, came to be. Today I will focus on this topic. I would like to share with you some of my thoughts.

Before the discovery of the double helix structure of DNA, scientists believed that life was so complex that it should be a very complex structure to make up genetic material, and many of them believed that proteins were the most probable. But they were wrong.

Proteins are too complex, too many degrees of freedom, and precisely for this reason, proteins cannot be genetic material.

Genetic material is heirloom. Diamonds can be heirlooms, gold can be heirlooms, because they are all stable and will not be changed, in the eyes of people, know what diamonds, gold should look like.

What can't be a family heirloom? Chinese have always had the idea of reverence for the ancients, especially worshiped the ancient sages, and cherished history, and then, one day, a historian was shocked to find that almost every generation of ancient history, literature, and stories will be transformed according to their own ideas, so that you can't find the original version.

Therefore, we have lost half of "The Art of War", we have lost half of "Zhuangzi", and we have lost half of "Laozi", not only the people spontaneously changed it, but the official will delete and change the classics every time, Dong Zhongshu in the Han Dynasty respected Confucianism, Li Shimin interfered with the work of historians because of original sin, "Yongle Canon" and "Siku Quanshu", the list goes on...... (The foreigner audience is completely confused)

Protein is a substance that directly interacts with the complex inorganic environment with energy and matter, which causes it to be easily influenced, changed, deformed, denatured, and lost by the outside world.

Why can't you keep yourself in direct contact with the environment? Because you have to maintain a balance with the environment, just as a sphere is the shape of all large celestial bodies, and protein is also a kind of 'sphere' that is a strange kind of 'sphere', and maintaining a three-dimensional geometry with the lowest energy consumption is the most labor-saving.

It doesn't matter that a prion is a life organism made up of proteins alone, it is neither a virus nor a bacterium, but a completely new life, or a half-life, which he reveals as the form closest to life as a single constituent of protein.

Prions have no DNA, no RNA, and cannot replicate themselves, and they proliferate by converting the normally functionally unclear PrPC (C is superscript) protein on nerve cells into a PrPSc (Sc is superscript) protein, which is exactly the same as the PrPSc protein, but folded differently.

This subverts the previous scientists' understanding that the primary structure determines the tertiary structure, and it is also one of the reasons why prions are very powerful, real viruses trigger an immune response, and prions are too similar to normal proteins for the immune system to expel them.

For us, this is bad news, for prions, it's the way it lives, because it can replicate itself, so it's a life form.

Prions can only be parasitic on animal nerve cells, without normal PrPC proteins, there is no material for them to replicate, and where does PrPC come from? It can only come through DNA or RNA, which is still very traditional.

At most, the replication of proteins can only find parasitic half-life organisms such as prions, and only DNA and RNA are not real genetic material that can really preserve themselves.

Why? Because RNA is two-faced, it binds to DNA and it binds to protein. Being able to bind to proteins inherits the nature of the interaction between proteins and the environment, and its stability is much weaker than that of DNA.

RNA is a very special form, and it is precisely because of its existence that it can build a bridge between DNA and protein. The DNA double helix itself is particularly difficult to interact with the environment, and it is highly stable, and the code used to preserve life is the most suitable, but it is not possible to be too stable.

If it is too stable and inflexible, it will not be able to adapt to the environment gradually, and once it reaches a certain tipping point, the DNA will be finished. We can imagine that the first real life can only be DNA, but there are countless friends who are exactly like it.

Countless isolated DNA came and went, created by chance, and then eliminated by drastic changes in the environment because of stubbornness.

Finally, one day, a DNA fragment meets a lifelong companion - RNA, which is equivalent to a channel for interaction with the environment, and from then on, every subtle change in the environment has more or less an effect on the DNA.

DNA is becoming more and more diverse, and so are the proteins it corresponds to through RNA, and the hydrophobicity of DNA and proteins keeps them firmly together, probably because of things like phospholipids that wrap them up. This was the beginning of primitive life. Phospholipids, on the other hand, are the main components of cell membranes.

DNA is the soul of life, RNA is the messenger of the soul, and protein is the disciple of DNA, which are the three core elements of life, all of which are indispensable and compose a great song of evolution.

DNA tends to be stable, proteins tend to change, RNA coordinates their pace, the mechanism that can replicate stably and sense the environment has finally emerged, and this is the great life.

Life perceives the environment and records everything it 'knows' through DNA, passing it on from generation to generation, and the fire is never extinguished, from the deep sea hot vents to the shallows, from the shallows to the land, covering the entire crust where there is liquid water, which has made us what we are now.

I donated $100 million to Columbia University to do one thing, which is to use mathematical and physical methods to study the prions I just mentioned, mainly using supercomputers to simulate biomolecules, simulate the folding of PRPC, although we can't see them clearly with an electron microscope, but we still have to understand them, and finally solve the pathogenicity of prions, and do some tiny work for the aging nervous system.

If 100 million doesn't work, it's 1 billion, if 1 billion doesn't work, then 10 billion, until all my resources are consumed, thank you for coming. Above.

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This speech, some people think it is wonderful, some people think it is ordinary, but his subsequent molecular computer architecture is very amazing, through the PCC, a platform with 20,000 programmers, he proposed a supercomputing architecture that simulates molecules, and uses the form of ICO to release molecular supercomputing cryptocurrency.

It turns out that it is not enough to build your own supercomputer, but also to attract nodes around the world who are interested in simulating protein folding to form a huge, cheap supercomputer, and the reward for nodes and the prospect of this technology in the future is where the value of cryptocurrency lies.

Bitcoin is making senseless and immediate SHA256 generation, a molecular supercomputing that is much more practical.

At present, this architecture is not decentralized, and Juchen's team still holds the leading power of technological evolution, but in the future, it is possible to decentralize it for the benefit of all mankind, or take another way to control it, depending on the future development.

This molecular supercomputing architecture is really similar to a mining virus, and it is once again rumored that the Night King who has manipulated tens of millions of mining nodes is Professor Juchen, and it is very popular.