When the parenchymal cells of an organ atrophy, interstitial (mainly fat) hyperplasia is often secondary, and whether there is a systemic mechanism that relies on paracrine maintenance, related to skeletal proteins or related to inhibitors, but the important thing is the mechanism of its hierarchy. 1 Nutrition, the cell to maintain the basic survival of part of the mechanism is deactivated, I think it is related to the rate of protein renewal, without enough supplement, the protein can only barely function, and the mechanism of the protein required to operate is high, can be accurately matched, this is the consequence of the destruction of coupling;2 oppressive, when the cell function can not continue to operate, the cell will produce learned helplessness, the mechanism of internal chaos and the mechanism of apoptosis coupling, self-destruction;3Disuse, the cell is a dynamic entity and a dynamic state, his performance matches its previous stateI think there should be some mechanism in the body to exclude these derived mechanisms of adaptation to previous conditions, just as the chemical equilibrium is in different proportions in different environments. The chemical signal of nerve impulses is an important recognition mechanism for the body to maintain its current state, as well as other endocrine organisms, and the overall construction environment of their role, that is, the probability space, where cells probabilitarily express their behavior.

Hypertrophy and hyperplasia are likewise information proliferations, the former tends to be volumetric and the latter to quantity, but the two are coupled and have a larger picture interpretation, that is, the projection of high-dimensional motion. Each cellular pathway can be seen as a dimension, and the various connections between different dimensions can collapse into fractional dimensions, and different levels can be established according to various probabilities. 1 Regeneration, the extension of structure and function depends on the stability of the internal iteration of the cell, and this mechanism can be derived from the more conservative pathway mechanism of hepatocytes and even stem cells, and here I see the mechanism as the object of operators and operations. 2 Over-regeneration, one view is that the inhibition mechanism has been lost, but this is a separation, and I tend to think that this is a complete mechanism, coupled but not the same as regeneration, which I see as the result of evolution, or related to the cell cycle. This can be related to cancer, cancer cells are the process of evolution, is highly unstable, like the electronic jump to a very high energy level, if there is no definite energy level so that it can release energy and finally stabilize at the energy level, that is, the evolution is successful, then it may diverge the transition, and this process is sustainable, stimulatory carcinogenic is to provide a certain condition is the cell continuous trial and error, when a batch of cells is eliminated, it is always possible to give birth to a strong stimulus-tolerant cell, and spread rapidly, which is a successful evolution of the cell, but not for the whole, it destroys the balance, the mathematical model of game theory can be applied to this。

Metamorphosis, because of stimulation, is metamorphosis. Or can it be seen as a symmetrical transition of the group, for example, the superficial epithelial cells of the pyloric region of chronic atrophic gastritis become similar to the mucosa of the small intestine, whether there is an internal overall transmission of information or looking at the migration of a certain gene, which I temporarily see as a change in the direction of choice of differentiation, because I do not recognize the absoluteness of differentiation, as a specific mathematical structure, it can do a series of transformations.

Causes of cellular damage: hypoxia, chemicals, physical factors, nutrition, endocrine, immune response, aging, socio-psycho-psychiatric factors, iatrogenic factors can construct a table to break down more basic pathways and build associations, like a database

Pathogenesis: 1 The destruction of the cell membrane, as a boundary, the change of the upper and lower limits of a function is bound to be the change of the internal function to make it inconsistent, and its lower functions include skeleton proteins, phospholipids, receptors, glycoproteins, etc. 2Reactive oxygen species, misintegration of chemical reactions 3 Effect of high concentration of calcium plasma in cytoplasm on enzyme activity 4 Hypoxia inhibits oxidative phosphorylation of mitochondria, which not only affects energy, but also has a certain inhibitory effect on suspended animation from a hypoxic state 5 Chemical damage, direct locking information entropy drops to a negative number, triggering equilibrium abnormalities 6 Genetic variation, root function disruption

Degeneration is morphological changes that can be eventually repaired, whereas necrosis is the result of severe degeneration

What is the coupling point of cell death, plasma membrane lysis, structural autolysis, and triggering acute inflammation?

Is the caseous necrosis caused by Mycobacterium tuberculosis associated with its eventual calcification?

Apoptosis is a genetic phenomenon that is temporarily seen as having fewer benefits from survival than from death

Granulation tissue is composed of new capillaries and fibroblasts, inflammatory cells, which foreshadows the coupling of the immune system with regeneration, reminiscent of the characteristics of stem cells of immune cells, which is the boundary of the human body

The collagen cellulose of the scar tissue is broken down to repopulate the cells and promote the migration of adjacent stem cells

Infection is regeneration, and immune cells tend to be intact and self-consistent

If thrombosis is regarded as a crystallization (conversely, it is a method of protein crystallization, a pipe, a flowing protein solution, and under certain conditions a single crystal may be obtained), then the thrombus can be removed by referring to the method that cannot be formed by crystals: adding electrolytes, changing temperature, etc

The common denominator of severe trauma, burns, malignant neoplasms, acute leukemia, sepsis is DIC (Hidden Markov)

Embolism and infarction should mobilize the nervous system to rapidly adjust the diameter of the blood vessels. For example, inflammation dilates small blood vessels

The relative separation of the environment, i.e., the reduction of the degree of coupling between the layers, is a prerequisite for tumors, and the construction of broad connections to avoid some cells falling into a competitive environment is the way to reduce the number of tumor cells in these evolved individuals

According to Lenz's law, there are always changes that hinder change, and the interstitium of the tumor has both a nutritional and supportive effect, as well as an inhibition of its growth such as fibroblasts and myofibroblasts

Lymphocyte infiltration of tumor tissue may not be an immune response, but a behavior similar to the collection of protection money, so that the immune function of the tumor does not recognize lymph can separate the tumor

Fabricate an envelope to turn malignant tumors into benign tumors

Cells adhere and migrate into the intima to promote atherosclerosis

Diseases that cause secondary hyperlipidemia: diabetes mellitus, hypothyroidism, nephrotic syndrome

Transmembrane transport, concentration difference, chemical potential--- absorption, transformation, distribution

The binding of the drug to plasma proteins, the difference in pH

Coupling, relational, dynamic connections

Projection is one of the ways we understand higher dimensions, and this is my understanding of molecular mechanisms

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