Chapter 27: Reflections on Holism
Sequences are used to couple hierarchies
andallofthesetogethergiverisetocellulartissueandanismmalfunctionorfunction。 The continuous collection of www.biquge.info levels of pen and interest is finally reflected at different levels
IntegratedStudy
somemighthaveasystematthelevelofcell。 The correlation coefficient of resonance is greater due to the different intensities of the coupling relationship between the levels of orthelevelofatissueinananorthelevelofthewholeanismoingbacktotheotherend, anditmaybesub-cellularlevels, and likeisaidbefore
howcellsbeetissuesandans coupling mode
The formation of sublayers helps in the formation of layers, like the channel proteins of the cell membrane
The combination of different chemical molecules as a hierarchy, it is important to look for regularities and quantify their concentrations available (hidden Markov)? Or backtrack a hierarchical sequence? Is this consistent with the hierarchical coupling of differential equations?
anizethesedatainanappropriatemanner
Avarietyofstatisticalandmathematicaltoolsgraphtheoryorworkanalysisgraph theory and network analysisprovideadeepunderstanding
There's a rightorwrongway that is probability, and different environments have different probability spaces, i.e., different biases
modelscantellusaboutsystemsbehavior
interactionbetweenponentsleadtotheemergenceofsystemslevelproperties
Interaction, i.e., the external nature determines the internal existence of the individual
setsofponents sets, which is a system of arithmetic
moleculesinteractandetogethertogiverisetosub-cellularmachinesthatformfunctionalunits molecular action and molecular hierarchy make up sublayers, which can ultimately be understood as basic units, i.e., our concepts, that can explain function
thetranscriptionalprograminhumanfibroblastscould,wouldrespondtoastimulus
howpropertiescouldemergefrominteractionbetweenbiologicalsignalingpathwaysandhowtheseproperties
cellswouldmaintainhomeostasis is robust, i.e. reductive, which is a tendency. Cells tend to be homeostasis
thesesubcellularmachinesinturngotoformcells。 The reaction force, i.e., Lenz's law, determines the existence of life, and all of them are related to interactions
physiologyhasalwaysprovideduswithquantitativedescriptionoffunctionsatthetissueandatthetissueandanlevel is not only quantifiable changes in physiological indicators, but also the groups formed by changes in indicators are also quantitative, anyway, searching
There are multiple levels, and there is also a time dimension. Different rules apply to different scales
Different behaviors such as the opening and closing of channel proteins are also a kind of sequence, which inspires us to 01 complex things, and then combine them into sequences, and finally different levels of coupling, such as the opening and closing of channel proteins, also represent a certain gene expression, that is, different levels of coupling
Reductionism is a kind of local approximation, which cannot be done for higher levels, and if we continue to deduce backwards from lower terms, can we finally reduce it to the power operation of a certain function? i.e. anti-Taylor decomposition?
The protein has its antibodies to fuzz the calculations, and the sequences have their corresponding antisense sequences.
Next is correlation analysis
Catabolism is 0, anabolism is 1, and life activity is a series of sequences and their operations
Metabolism constitutes a unified whole, i.e., the transition between 1 and 0, and at the same time there is a patterned transformation, that is, a structured transformation
Different processes are also a coupling: absorption-metabolism-excretion
A fine regulatory mechanism that regulates the intensity, direction and speed of metabolism, i.e., the different directions of probability
Each metabolite has its own common metabolic pool: a base or node
ATP is a common form of energy utilization in the body, and the common form of mechanism is a sequence
Each has its own characteristics: different ways and different functions
The distribution of different tissues, the functions are high-level coupling
Cellular level-hormone-whole: the increasing level, in which the emergence of the middle level seems to be explained by evolution, the overall level is like our senior managers in reality, pay attention to the art of management, both under the following system, but also to make everyone work in one direction; The smaller the scale, the greater the closure, which is also conducive to regionalization and exerts a marginal effect
The linkages between sugars, lipids, and protein metabolism: the basic units are determined, the relationships are constructed, and they can be coupled in a larger dimension, like mathematical self-consistency, they can be mapped to multidimensional processes, but ultimately convergent, which is reflected in the relationship of mutual transformation. But complete translational conversion is not possible, otherwise it can be topologically integrated, and there is no difference
The transformation of probability is necessary, and in special cases it will be irreversible, which illustrates the impossibility of some transformations
The brain is an excellent model for understanding these sequences, as the brain perceives movement through the processing of a variety of signal sets of different intensities and properties, and is able to selectively read information and focus on larger dimensions
The metabolism of any energy source is dominant, and it can often inhibit and save the degradation of other substances because they are coupled to the same energy system
The interconnectedness of metabolism is the higher dimension of matter, which is also the wave function
This can be statistically simulated
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