Chapter 46 Phenomenological Medicine II

What is the nature of things? The nature of things is determined by the main aspects of the main contradiction of the main contradiction. Therefore, if the main aspect of the main contradiction changes, the nature www.biquge.info of the thing changes. Here, we see the development of contradictions and contradictions as wave functions, and the nature of things is the eigenvalue of them, so that we can guide reality in turn.

A wide variety of drugs are likely to interact with each other and cause adverse reactions. This interaction is first simplified to a harmonic oscillator system, so that there is a certain amount of distribution

Serious adverse drug reactions, such as aminoglycoside antibiotics, cause damage to the auditory nerve in children, which is the main cause of acquired deafness; The use of tetracycline in children is too long, resulting in enamel development disorders, bone growth inhibition, and serious damage to the health of a generation; Long-term use of gentamicin, kanamycin, and polymyxin can lead to kidney damage and even renal failure; Long-term use of some antibiotics causes hematopoietic dysfunction; The treatment of severe diseases with broad-spectrum antibiotics and synthetic antimicrobial drugs may lead to dysbiosis and even superinfection

A variety of broad-spectrum antimicrobial drugs, or even a combination of drugs, have the possibility of multiple hits

Syndrome differentiation and treatment are different from "symptomatic treatment" and what modern medicine calls "disease differentiation treatment". Different syndromes can occur at different stages of the disease, and the same pattern can occur in different diseases during their development. Therefore, the treatment methods for different syndromes of the same disease can be different, such as edema (nephritis) patients, initial fever, chills, edema, unfavorable urination, etc. are "feng shui syndrome", and the treatment should be to promote lung sweating, dilution and swelling; In the later stage, backache, cold limbs, chills, pale face, edema, etc. are "kidney yang deficiency and failure syndrome", and the treatment should be warm and the kidney is supported. As long as the syndrome of different diseases is the same, the same treatment method can be used, such as anal prolapse, gastric prolapse, uterine prolapse and other diseases, all of which are caused by the sinking of central qi, and can be treated by the method of invigorating qi and raising yang, which is what traditional Chinese medicine often says "the same disease is treated differently" and "different diseases are treated at the same time"

That is, the treatment of the symptom, i.e., the stage of development of the disease, is the most important, and it is regarded as a wave function, which is an eigenvalue of multiple wave functions, and exerts influence on the network formed by it to normalize it

Yin and Yang are essentially dichotomous quantums

The four diagnostic parameters are an eigenvalue determined by multiple wave functions, that is, the diagnosis

The 20/80 principle is a distribution that satisfies a certain probability, or is rooted in the principle of entropy increase, which is related to a marginal quantity

Divide the importance, pay attention to the use of the margin, and do the important first

The eight outlines are not static, but change according to certain conditions; The symptoms indicate that the fever is aggravated, and the symptoms are that the disease is cured; The hot evidence becomes the cold evidence, and the empirical evidence becomes the false evidence, and most of the good is invincible to the evil; The cold syndrome becomes the hot syndrome, and the false syndrome becomes the empirical evidence, and most of them are the gradual recovery of righteousness. Although the Eight Platforms have their own different witnesses, they are rarely simple and isolated, but there are complex relationships of "concurrent" and "intermingled", and sometimes there are "false appearances". The quantification of TCM may be quantized, explained by the wave function

The four medicinal properties of cold, hot, warm and cool, as well as the various medicinal properties of the same herb with different proportions, are all the same self-consistent, and the wave function model satisfies this kind of inter-level operation

The focus of genetic manipulation is on the xenointegration of genes, whose plasmids, viruses, etc. are only vectors

Structural features of sequences such as restriction enzyme recognition sites, transcription start and end signals, reverse palindromic sequences, and sequence repeats

The general law for predicting three-dimensional structures from one-dimensional sequences is necessarily a coupled state, which can be expressed by differential equations. First of all, we accumulate data based on experience, and predict some sequences that play as structural nodes or markers based on the crystal structure data of proteins, which can be regarded as first-order quantities. Different DNA, the various relationships of the amino acid sequence itself, such as proportions, the interaction of small collectives divided by different lengths are second-order quantities, and the total coupling of various wave functions such as rings is also a wave function, which is a three-dimensional structure, and there can also be a fourth-order above, that is, the interaction between proteins. Now we can predict functional similarity by the homology of the sequence, which is a useful approximation

Probabilistic spaces, abstractions in different combinations, orthogonal of multiple projections, changes in operators and their commutations

The effects of single mutants can be counteracted in the network, but we are still accumulating data at this stage to arrive at a pattern. However, gene cloning accelerates this process by introducing isolated genes into the original cell type, different cell types, and different organisms; By introducing specific variants at any location in the gene, these studies support single sequence analysis

Antigens of the virus are expressed on the surface of yeast cells for use in vaccine research

DNA must be integrated into the network of chromosomes in order to be expressed

The model is based on probability, Bayesian statistics

Evolutionary bias towards peptides that function stably

The long-range effect of amino acid sequences is difficult to determine-local structure prediction (this is the limitation of reductionism, and in order to break through, it is necessary to consider the holism of multi-level system coupling, but the calculation is difficult)

The complete three-dimensional structure is partly determined by long-range interactions, but also by short-range interactions and their combinations

Quantumity is determined by its scale, and it is unreasonable to use the analogy of the scale of reality

Is the discontinuous energy level of the quantum more continuous core? Or is this a coupling of nature

If the sparseness of the particle does not isolate the interaction, or its action is a higher-dimensional effect, and our reality of a single particle monitoring is a low-dimensional effect, then it is difficult to deny that its behavior is a high-dimensional projection

Limits are also included in systems that are coupled to themselves, as classical mechanics is to quantum mechanics

Velocity is a limit, and the limit of quantum mechanics has its fluctuating variation, i.e., the probability distribution. The conventional concept of physics is no longer applicable, and the principle of uncertainty illustrates this, and we must pursue other ways of interpretation, and fundamentally reform our concepts; If the value is used as a mathematical device, it should be replaced by a relational connection. Quantification is a hurdle that cannot be overcome, but we can discuss the various correspondences between the two complex coupling systems, but we still need to quantify to determine the change of indicators, which is stuck in an endless loop. But it's also a quantum state. Based on the knowledge of biology, we put forward a conjecture that there are two sets of principle systems of coupled states, one like DNA, and the other like epigenetics to modify and selectively express the previous system

Massive amounts of information are bound to emerge according to probability, such as Kepler's laws and Newtonian mechanics, so let's play with biomechanics? There is a transfer of concepts, but the coupling of levels is also necessary, and this brings us to quantum mechanics and differential equations.

For the solution of differential equations, the dichotomy embodied in the ancient idea of yin and yang may be helpful, that is, regardless of the specific way of coupling the various levels within the equation, the cost/eigenvalue complementarity of each level is directly called up (or the solution of the probability network), and then added up (I prefer the hierarchical coupling of the probability network). For example, the method used by Wang Mengying in the treatment of malaria, he does not directly use anti-malarial drugs, but he analyzes the sick person, he sees that you have yin deficiency, he gives you yin, sees that you have blood stasis, he gives you stasis, sees that you have insufficient yang qi, he gives you yang, and when he sees that you are damp, he discharges your dampness, in short, he focuses on regulating your self, and when your body is running normally, your own resistance comes up, and you yourself will be able to fight out the external evils.

The eight-gang dialectic, yin and yang, cold and heat, the surface and the inside of the void and the real are high-dimensional dichotomy, which refines certain symptoms into various levels, and then complements each level separately. (A bit like an orthogonal experiment, where the rest of the hierarchical complementarity cancels out the effect, leaving only a pair of variables for us to observe the relationship) It can attack the jade, and the foreign system directly interacts with the original system, just as the eigenvalues are directly substituted into the differential equation, and the various terms of the differential equation are artificially processed to form a cycle, that is, what we generally think of as a healthy state.

Actually, differential equations are very much to my liking, mainly because they have a sense of beauty. Formally, the sum of the levels can be a constant quantity (ax''+bx'+cx=0), and they can also be coupled to each other (ax''x'1+by''y'=0), and each derivative of x is regarded as a level; Secondly, its solution is also a differential equation, with various possible values such as c1 and so on, and its solution is generally in the form of a combination of exponential e and trigonometric functions, which are periodic.

I had always thought that the nesting of hierarchies could be done infinitely. As Whitehead said, when a system of formal logic appears with a paradox, it is encompassed by a larger system of logic, in other words, by making the original system of logic a subset of a larger system of logic. However, the proposal and proof of Gödel's incompleteness theorem point out that the use of layer-by-layer extension to expand the formal logic system cannot eliminate the contradiction of its sum! According to the form of motion of Brouwer's fixed-point principle in topology, in the continuous iteration of the hierarchy, total/at least one level can be used as a representative or eigenvalue of the overall hierarchy. In this way, the coefficients in front of some of the variables I've always hated are actually the ones that are destined in multi-level iterations.

Specific cell combinations, such as species, number, distribution, relative proportions, and proportions of objects need to be selected

The treatment of HIV can not only rely on various levels of inhibitors, but also cooperate with certain network structures to select certain activators to affect cells or molecules

The occurrence of complications is undoubtedly the probability of reorganization after the destruction of the network structure, such as diabetes, osteoporosis, coronary heart disease, stroke, etc

The choice of marker, in the molecular pathway of action, is related to the proportion of various molecules

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