0079 Where There's a Will, There's a Way?
October 8th.
Yi Yang has returned to school and started his normal study life, although he is still reluctant to communicate with the classmates in the new class, but he has become closer and closer to the classmates of the affiliated college in his previous life.
Meanwhile.
RB Tokyo.
Utsumi got up on time to wash up as usual, and after eating breakfast and kissing his wife goodbye, he grabbed his briefcase and rushed to the subway station to go to work in the suburbs.
The place where he works is called the Institute of Life-Derived Biology, which is actually a family research institute handed down by Utsumi Junhei's grandfather, and has been engaged in research on blood and vaccines, which can be regarded as a family history.
In addition to the director and chief researcher of the Institute of Life Origin Biology, Toshihei Utsukai, there are only two assistant researchers left, Konosuke Shimoto and Hidetomo Matsudaira, and there is no one else.
The equipment of the institute can be regarded as absolutely first-class in RB and even in the world, but these equipment have little to do with Utsumi Junhei, and they were purchased by his grandfather and father. Although Utsumi Toshihei once studied at prestigious universities in Europe and the United States, and his professional knowledge and technology are more solid than his parents and grandparents, when it comes to business talent, it is really not worth mentioning.
Had it not been for the RB government's introduction of a series of supportive policies to encourage biotechnology transfer and commercial development at the end of last year, which gave Utsumi a glimmer of hope for perseverance, I am afraid that he would have abandoned the family research institute and sought other positions in large biomedical companies.
After arriving at the research institute, Konosuke and Matsudaira Xunzhi were already busy in the laboratory, these two were students brought out by Utsumi Shunpei's father, and their professional and technical level was quite high, but their emotional intelligence and social skills were average, if it weren't for this, it would be impossible to continue to work hard under Utsumi Shunpei.
After putting his handbag in the office, changing his clothes, and putting on an isolation gown to disinfect in the disinfection room, Utsumi Toshihei enters the laboratory.
Yunosuke Sumitomo and Tomotomo Matsudaira just glanced up when they saw him coming, and they lowered their heads and continued to busy their experiments.
Utsumi Toshihei took out a set of vaccines prepared yesterday from the culture tank, put them under a high-powered microscope, and began today's experiment.
His main focus now is on Mycobacterium tuberculosis vaccine, which is simply a vaccine to prevent tuberculosis. In fact, at the beginning of the last century, two French bacteriologists, Camed and Jielan, had jointly successfully trial-produced an artificial vaccine to prevent tuberculosis, also known as "BCG". The vaccine, which protects against severe tuberculosis in children, is given at birth by a maternity hospital, but because it is only an attenuated vaccine, it has limited protection and has little protection against adults.
Due to the problem of family history, Utsumi Junhei took a different approach to the development of Mycobacterium tuberculosis vaccine, combined with the attenuated prevention process of BCG, and thought that a harmless bacterium that can engulf Mycobacterium tuberculosis could be developed, and the purpose of prevention and treatment could be achieved by injecting this bacterium to engulf Mycobacterium tuberculosis.
In this regard, his parents and grandparents had already studied it, so he was full of confidence. As long as this bacterium is developed, he is confident that he will be able to get investment from the government and large conglomerates, and he will be able to cope with the current economic difficulties.
I don't know if God was moved by his persistence, or if it was some other reason, his experiment at the beginning of today went extremely smoothly.
When he injected Mycobacterium tuberculosis into the sealing tank, he saw that all the tuberculosis bacteria had been engulfed by the newly cultivated group of bacteria from yesterday, and the new bacteria did not show obvious changes.
"Oh my God, Konosuke, Xunzhi, come and have a look!" Utsumi Shunhei was overjoyed and called out to the two assistants in surprise to come and see his results.
Konosuke Sumitoku and Xunzhi Matsudaira are mainly responsible for the cultivation of new strains, and when they heard Utsumi Shunpei's surprise call, they hurriedly put down their work and came over.
Utsumi Shunpei carefully injected another set of tuberculosis bacteria, and right under the noses of Konosuke and Matsudaira Xunzhi, the new bacteria devoured the tuberculosis bacteria without any pressure.
"This ...... Is this a success?!" The two assistants' eyes widened suddenly, and they were shocked by the scene in front of them.
"Is there any mutation?" Matsudaira Xunzhi was more detailed, and hurriedly asked after letting go of the microscope and giving Konosuke to Sumito.
"No... No! There is no sign of any abnormality!" Konosuke Sumitomo carefully observed the nucleus and membrane of the new bacteria, and his heart began to tremble when he saw that there was no abnormality.
The three of them immediately hugged each other, tears overflowed in their eyes, the three of them have finally achieved results today after nearly ten years of perseverance, from a young man in his twenties to a middle-aged uncle now, he will soon see success, and the joy in his heart can no longer be suppressed.
After cheering, the three of them called up the cultivation record of the new bacteria, the new bacteria was labeled "T36681", and began to repeat the test.
A success can only indicate that the research direction and cultivation direction are right, but it does not mean that the whole experiment is successful.
From this day on, the interest of the three of them became higher and higher day by day.
Each day's culture tank was taken out by three people the next day, and then each of them injected tuberculosis bacteria for testing.
With the exception of a few cases where new bacteria in the tank did not survive due to operator error, the vast majority of trials were successful.
"Based on the performance of T36681, I think it can not only engulf Mycobacterium tuberculosis, but also other viruses. I don't know if you've noticed, but when engulfing and digesting Mycobacterium tuberculosis, the cell composition of T36681 does not change at all, and it is clear that Mycobacterium tuberculosis is just a piece of cake for it. "After more than a month of observation, Utsumi Junhei suddenly thought that he could conduct more tests on T36681 today.
"Let's start with a common virus and test its tolerance. Matsudaira thought for a moment.
Konosuke Sumito's eyes have been staring at the microscope, carefully observing the performance of T36681, and at this time, he didn't know what was going on in his head and was suddenly stunned, and then he instantly became clear, thought of a question, and said: " Two, I injected Mycobacterium tuberculosis five times, T36681 only split once, obviously its reproductive ability is insufficient, although it survives long enough, but the lack of division and reproductive ability is definitely a major drawback, I think we can try to inject other viruses, analyze whether it is because of insufficient food provided and its lack of energy or other reasons. ”
"Well, I've also noticed this problem, and I've thought about it comprehensively, so we have to give it a try. Utsumi Junhei's expression tightened when he heard this.
If the division and reproduction rate of T36681 is too slow, the final result will definitely be an increase in the cost of treatment, which will undoubtedly cause a serious obstacle to subsequent commercial promotion, and this problem must be solved in the laboratory.
With a goal in mind, the three scientific maniacs began various experiments day and night.