Chapter 187: The Value of Small Molecule Compounds
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"Okay, Professor Bruce, as a member of the Scripps Research Institute, I would love to work with you again in the Department of Neurobiology!"
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"Of course, you know, I've been very busy, yes, very busy, so I'm afraid I'm going to have to wait for a while. β
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"Okay, I'll get back to you then. See you soon!"
Putting down the phone in his hand, Tian Lu let out a long breath, tilted his body, and fell on the sofa.
Seeing Tian Lu's tired Nirvana, Ye Lan couldn't help but feel a pain in her heart, quickly got up, knelt on the sofa, and began to massage Tian Lu's temples, and complained in a low voice: "This Professor Bruce, doesn't you know that it's night in Kyoto?
"Hehe, of course he does. β
Patting Ye Lan's little hand, Tian Lu smiled bitterly: "But he thought it was not too late here, and it was more appropriate to call." β
For Professor Bruce, Tian Lu has always been grateful and respectful. During his two years at Scripps Research Institute, Professor Bruce gave him great trust and support, which Tian Lu always remembers. Now that he has a new research breakthrough, and there is still a lot of room for development in the future, the other party took the initiative to seek cooperation, and he had no reason to refuse. What's more, Tian Lu originally had such a thought.
It's just that it's true that as Tian Lu just said, he has been too busy lately to spread out so many things for the time being. So I had to suppress this idea for the time being.
The publication of these two articles has only just begun its impact on Tian Lu!
Because of various subjective and objective factors, in China, or around the field road, this kind of influence will not have anything in a short time, but in foreign countries, it has indeed set off a lot of waves. In just two days, the phone calls in the laboratory were almost blown up, and there were even many calls directly to Tian Lu's mobile phone.
There are three main types of calls to find the value of small molecule compounds in Chapter 187.
The first is pure researchers. It's exciting, it's curious, and of course it's more about communicating. I want to have an academic discussion with the author of the article on the phone. For this kind of call, Tian Lu is very polite, and generally communicates with the other party for a period of time, explains a few key issues, and then ends the conversation euphemistically.
The second is the so-called cooperation that seeks cooperation β, which not only refers to the cooperation in research in related fields, but also universities and other research institutions that want to invite Tian Lu to do academic exchanges, and academic conferences that want to invite him to give speeches. (There are many of them, including Professor Meghan, who had several relationships with each other back then, and invited Tian Lu to Copenhagen to attend this year's General Assembly of the European Federation of Neurological Societies.)
The third is the Chinese branch of several multinational pharmaceutical giants.
The idea of these pharmaceutical giants is also very simple, that is, they want to have experts and scholars from their respective companies come to the door to communicate. Of course β, the so-called exchange must have a strong commercial flavor, and Tian Lu also understands in his heart that once the other party confirms that the small molecule compound he discovered is indeed of practical value, then the next step, I am afraid that cooperation will be proposed, of course, it is more likely to be acquired.
Let's be honest. Tian Lu did not reject this idea of the other party.
At the beginning, to purify this small molecule compound, on the one hand, it was for the needs of research, but on the other hand, Tian Lu originally planned to use it to raise a lot of money.
As a product in the laboratory, this small molecule compound must go out of the laboratory and into the clinic if it wants to play its most important role. However, in order to become a marketed drug, it must strictly follow a series of processes before the new drug is launched, and complete preclinical experiments, clinical trials and other projects.
This process is very longβ the pre-bed experiment takes three or four years, and the clinical trial is divided into several phases, each of which takes at least a long time! And in addition to the time span is very long, the cost of various experiments is also extremely high, even if it escapes the difficult drug screening stage, the success rate is guaranteed to be 100%, but the follow-up process also requires at least two or three hundred million US dollars.
For Tian Lu now, it is obviously impossible to complete the follow-up work by himself, and his only choice is to transfer this small molecule compound.
Of course, domestic companies should not think about it, not to mention whether they have the strength to buy the patent ownership of this small molecule compound, just saying that the follow-up long time and high investment are enough to discourage them and retreat.
The companies that dare to call Tian Lu have the strength to do it, that is, those multinational pharmaceutical giants!
Tian Lu saw this very clearly a long time ago, and he also knew that his only choice was to find a multinational giant with the best conditions and sell the patent rights!
It's just that how to sell it, Tian Lu must be calculated wellγγγγγγ
"What do you think?"
Looking at Tian Lu's Nirvana with his eyes closed and contemplative, Ye Lan couldn't help but ask with concern.
Opening his eyes slightly, Tian Lu said a little half-jokingly: "I'm thinking about how much the small molecule compound I found can be sold for!"
"How much do you think you'll sell, and will it be worth more than the one you designed?"
Although she knew that Tian Lu's tone was very joking, Ye Lan still continued to ask curiously. She knew that Tian Lu had just published two very heavy articles, especially the small molecule compound, which must be very valuable, but she had no idea how high the specific value was.
"Compared to that set of equipment?"
Tian Lu was slightly stunned, and then smiled dumbly.
Stunned by Tian Lu's laughter, Ye Lanjiao blinked her big eyes, and asked with some confusion: "What, isn't there any comparison?"
"Of course. β
Tian Lu nodded without hesitation and said with a smile: "Although that set of equipment is also great, after all, the sales volume is limited, but for a drug." In particular, the value of drugs with a wide range of applications but no competitors is much higher. β
stared at a pair of big black eyes, Ye Lan's expression was extremely cute at this time.
"Do you know Lipitor?"
Gently pinching Ye Lan's little nose, Tian Lu asked with some amusement in his heart.
"Of course I do!"
Wrinkled her nose with some dissatisfaction, Ye Lan nodded vigorously. What are you kidding, how can Ye Lan say that she is also a regular clinical undergraduate. And in order to get into the USMLE, I went to be a resident, but I put a lot of effort β into it, can I not know the famous drugs?
Raising his eyebrows, Tian Lu smiled: "Then you can go back and check on the Internet, when Ruihui Company acquired Lipitor." How much money did you get?"
"That's a lot!"
Without even thinking about it, Ye Lan made a judgment. Even if she doesn't know, she knows that as the best-selling drug, the price is definitely not low. However, after reacting, Ye Lan's eyes widened again: "What do you meanγγγγγγ The value of this small molecule compound you found can be compared to Lipitor?!"
Ye Lan's surprise is not trivial!
"How is this possible?"
Tian Lu smiled and said: "I'm just giving an example, β a small molecule compound is just a laboratory product, and it is still unknown whether it can finally enter the clinic." Besides, even if the scope of application is wide, it is still far from Lipitor, after all, the number of audiences is still far away. So I want to sell it for that price. It's just a dream!"
Inexplicably, after listening to Tian Lu's explanation, Ye Lan was slightly relieved.
Indeed, if the value can really be compared to Lipitor, this small molecule compound is really too terrifying. I'm afraid it's going to be too much for her to bear.
"Butγγγγγγ β
After a slight pause, Tian Lu smiled slightly: "If this small molecule compound can enter the clinic, its value may be more reflected in the future." β
Although he said this, Tian Lu certainly understood in his heart that this small molecule compound could definitely enter the clinical field. Moreover, with the improvement of the blood-brain barrier theory, more and more data on the passage of drugs through the blood-brain barrier have been collected and sorted. It won't be long before breaking through the blood-brain barrier to treat central nervous system diseases will become a reality, and then, it will be time for this small molecule compound to truly show its value!
Therefore, Tian Lu has secretly made up his mind in his heart. It is absolutely unacceptable to sell the ownership of a patent at one time, and it is absolutely impossible for the selling price to truly reflect its value until it enters the clinic, no matter how important this small molecule compound is. You must be the same as the set of equipment you sold to Weisen Company, and get the later sales commission!
And whether it is the first payment or the later commission ratio, it must be much higher.
For money, Tian Lu is extremely hungry now.
Even with such outstanding results, Tian Lu does not expect to apply for scientific research funds or anything to support his subsequent research. For him, who has a future system, there are too many topics to carry out, and they are too big, even if he can apply for the maximum amount of financial support, it is undoubtedly not enough!
Basic research is inherently money-burning, and for the study of Tian Lu, the huΔ fee is even more expensive. In order to fully master his own research, Tian Lu must raise a huge amount of funds on his own, so that he can completely eliminate external interference and really do what he should do.
But now the most important thing is to find a suitable opportunity, preferably to bring these companies together, so that the field can have a comparison with each other. And this opportunity is better than in Kyoto, and Taro really doesn't want to let his normal life be affected too much.
Thinking of this, Tian Lu no longer hesitated, calculating that it was daytime in Europe now, so he picked up the phone and dialed a phone number he received yesterday.
"Hey, hello, I'm Tian Lu from the School of Medicine of Huaguo Jingshi University, please find Professor Megan!"
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"Professor Megan, I agree to attend next week's General Assembly of the Federation of Neurological Societies and, as you said, to give an academic presentation at the Congress, and the title of the presentation is γγγγγγ (To be continued!!
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