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"Osteogenesis hypoplasia, also known as brittle bone disease, is a group of rare connective tissue diseases characterized by increased bone fragility and disorders of collagen metabolism. Pen @ fun @ pavilion wWw. ｂｉｑUｇE。 The typical clinical manifestations of INFO are multiple fractures, short stature, blue sclera, hearing loss, and dentin hypoplasia that are hereditary and familial, and the incidence of this disease is mainly caused by mutations in the Col1A1 or Col1A2 genes encoding the type 1 procollagen A chain. The modern treatment principles of osteogenesis imperfecta mainly include three aspects: rehabilitation exercises, drug treatment, and surgical deformity correction and intramedullary fixation. Zhao Jianwei talked about the basic situation of osteogenesis imperfecta.

"This case of osteogenesis imperfecta in our hospital is due to a genetic defect caused by a consanguineous marriage. It also lasts for a long time, and both the patient and the patient's family suffer for a long time. Currently, I am living in a new inpatient area that has been temporarily added to our hospital. It is one of the patients who have benefited from the Group's special subsidy program. Zheng Suyue also briefly talked about the patient's financial support.

Next, I would like to ask our experts to talk about the treatment options for this case of osteogenesis imperfecta. Don't limit yourself to the few conventional treatments Dr. Zhao just mentioned. As Dr. Zhao said just now, conventional treatment methods can only prolong the life of the patient, but cannot completely cure it. Qin Chuan attaches great importance to this case, and he is absolutely determined that if he wants to help the patient, he must do good things to the end.

Qin Chuan also has a plan, from now on, Han Academy will begin to tackle all kinds of incurable diseases in a planned way, and then systematically promote it in Han Ding Hospital. In the past, Han Academy was constrained by the economy, and Qin Chuan could not do these things, but now it is different, and Han Academy can increase investment in the treatment of difficult journals. Moreover, H&Q's medical technology reserves can also achieve this goal.

Song Rui was the first to speak, "I think we can use gene repair and modification technology to fundamentally treat diseases like osteogenesis imperfecta. From the initial gene modification agent to the current gene primary enhancement solution, the development has been successful. The R&D department of H&Q has made great strides in this regard. We already have the tools to apply these technologies to the treatment of various genetic diseases. ”

"Dr. Song, if you were asked to develop a treatment for osteogenesis dysplasia, how long would it take?" Qin Chuan asked.

"It doesn't take much time, after all, the defective gene is known. We only need to study the mutation mechanism of the Col1A1 or Col1A2 genes, as well as the repair methods of the Col1A1 or Col1A2 genes. It should take about a month, and the results should be obtained. Song Rui thought for a while and said.

Qin Chuan nodded: "But have you taken into account the patient's situation." As far as I know. The patient has been waiting in line at Han Academy Hospital for almost a month, and if you wait for your medicine to come out, it will take more than a month. In fact, when the patient was transferred to the new inpatient unit, the patient's family was already suspicious of Han Academy. If we continue to delay treatment, what do you think might happen? There is a time when we have to think not only about the treatment of the disease itself, but also about the patient's family situation. But Dr. Song can start researching. But we have to be prepared for something else. Everyone went on to say. ”

"Dr. Qin, now clinically. Osteopeptide injections are used to treat osteogenesis dysplasia. Osteopeptide injection is a polypeptide active substance, the pharmacological effect is to regulate bone metabolism, stimulate the proliferation of osteoblasts, promote the formation of new bone, regulate calcium and phosphorus metabolism, and increase the deposition of bone calcium. It was Li Yongming who spoke.

Sun Chen also continued: "We can use targeted drug technology to enhance the effect of bone peptides. Although it cannot cure the patient's disease at its root, it can quickly alleviate the patient's condition. ”

Kang Mo also said: "I think Chinese medicine can also play a role in the treatment of osteogenesis imperfecta. Using bioelectric acupuncture techniques, specific developmental stimulation can be stimulated. We just need to give the patient the appropriate developmental signals. It can stimulate the patient's development in a certain way. Traditional Chinese medicine works wonders in this regard. ”

Everyone tried their best and came up with many treatment options.

Qin Chuan recorded all his thoughts, and everyone quieted down, Qin Chuan was the main treatment of this case, and it was naturally up to Qin Chuan to make the decision in the end. Qin Chuan also attached great importance to this treatment. In addition to experts from multiple departments, researchers from the R&D department were also gathered. Obviously, it is necessary to completely tackle this disease.

"You have come up with a lot of very good treatments. Based on everyone's opinions, I have developed a comprehensive treatment plan of integrative medicine. Prior to this, the distinction between traditional Chinese medicine and Western medicine was very clear in Han Hospital. However, with the improvement of our H&Q technology, we also feel more and more that traditional Chinese medicine and Western medicine are not completely incompatible. At the very least, the purpose of the two is the same. All are to cure the patient's disease. Since there is a common purpose, we are able to find common ground in them. As long as we can find this commonality. It will be able to find the combination of Chinese and Western medicine. This time, I think everyone did a great job. This is a true integrative medicine. Rather than using the combination of East and West as a gimmick. In the end, Qin Chuan was inclined to apply the two completely incompatible systems of traditional Chinese medicine and Western medicine to the treatment of this case.

During the ward rounds, the large influx of white coats made Song Xingben startled. Good fellow, a dozen white coats came in at once, and the ward was packed.

"Brother Song. Our dean attaches great importance to Xiaobao's condition and personally takes over the treatment of your grandson. Today, a large number of senior experts from Han Academy Hospital were organized to consult on your grandson's illness. This time, you can put your mind at ease. Professor Liu walked into the ward and immediately told Song Xingben an exciting news.

Song Xingben was flattered, and hurriedly stood up, thinking that Qin Chuan and his party kept bowing and nodding.

"Don't be restrained, old man. We came here today to tell you about the treatment plan for your grandson Song Xiaobao. After the discussion of the expert group, we have developed a very comprehensive treatment plan, and we will have a dedicated medical staff to introduce the treatment plan to you later. With your consent, we will immediately implement a treatment plan to treat Xiaobao's illness. You can rest assured that Xiaobao's treatment is still very optimistic. Don't have psychological baggage. Qin Chuan said.

"Thank you, thank you. How to treat, we all cooperate unconditionally. How much treatment is needed. Even if I can't give it now, I will let my son and daughter-in-law work hard to make money to repay it in the future. Song Xingben was moved to tears. He had heard too much bad news, and even some well-meaning doctors told himself privately that it was unlikely that his grandson's illness would be cured, so that he should not be too persistent. Although Song Xingben knew that they were well-intentioned. But he couldn't give up. This is my grandson. A living grandson. How can you give up? Right now. He finally heard good news.

"You don't have to worry about the cost, now Xiaobao's disease treatment has been approved as a research project of Han Academy, and all expenses will be provided by the project funds. However, in order to completely cure Xiaobao's disease, we will adopt some new treatments. I hope to get the cooperation of the family and the patient. Qin Chuan said.

Professor Liu hurriedly explained: "At present, some conventional treatment methods that are more commonly used can only temporarily alleviate Xiaobao's condition. To this end, Dean Qin and other senior experts have studied many new treatment options. The purpose is to make Xiaobao a normal person completely. Live a normal life. It also allows many patients like Xiaobao to completely get rid of the troubles of illness. ”

"That's a great thing. Our family will definitely support you! Dean Qin, please cure Xiaobao's illness. The boy had this disease. Didn't have a good life. What he hopes most is to be able to go to school like a normal child. Xiaobao is eight years old this year, and all children his age are already in the second grade. Every time I walked past the school gate with Xiaobao, the child had to stare at the elementary school gate for a long time. Song Xingben said this, and choked up a little.

"Don't worry. Xiaobao, uncles and aunts will definitely let you walk into school like a normal child. Qin Chuan said.

Song Xiaobao had a smile on his face: "Thank you, uncle." When I grow up, I want to be a doctor, to treat sick children like me. ”

"Okay, study hard, and come to our Han Academy to study in the future." Qin Chuan touched the child's head.

That day. All kinds of treatment instruments advanced Song Xiaobao's ward and began to treat Song Xiaobao's illness.

First, acupuncture is performed with a bioelectric acupuncture device. Although Song Xiaobao's stunted bones could not grow quickly, Song Xiaobao's body quickly entered the best state. After the injection of targeted drugs, Song Xiaobao's recovery speed was very fast. In less than two weeks, Song Xiaobao's bone strength was enough to support him to do some simple exercises. He can get out of bed and walk around, and he doesn't look much different from a normal child.

"Grandpa, can you let me go outside?" Song Xiaobao looked out the window. The green belt around Han Ding Hospital, which is as beautiful as a garden.

"That's not going to work. Xiaobao, your current situation has changed a lot. But the doctor said your bones are still fragile. It hurts easily. Once injured, it will affect your healing progress. Let's not go outside and watch TV in the ward, okay? Song Xingben was taken aback. He also wanted his children to go out and get some fresh air. But the grandson is still a sick person after all.

"It's okay, you take the kids outside for a walk. No problem. However, children should not be allowed to do strenuous exercise. With a little attention, there's nothing wrong with that. Qin Chuan, who had just walked into the ward, immediately met Song Xiaobao's request.

"Great!" Xiaobao jumped up excitedly.

"Don't jump!" Song Xingben was very nervous.

"Don't be nervous, Xiaobao is doing very well. There is no big problem with such a magnitude of movement. Qin Chuan said.

Qin Chuan looked at some of the historical records of the various instruments in the ward and nodded with satisfaction. The treatment methods employed by Han Academy Hospital are very effective. The effect is much better than the current treatment methods used at home and abroad. Even if Song Rui's genetic repair technology is not used, after this treatment, Song Xiaobao only needs to go to Han Academy for a short-term treatment regularly to live like a normal person. Song Xiaobao's development will not be affected too much.

Watching Song Xiaobao bounce out of the ward, Song Xingben chased him out nervously and relieved, and Qin Chuan was also in a very good mood. Being able to see the patient slowly getting better in their own hands is a heavy sense of accomplishment.

"It's better to be a simple doctor." Qin Chuan sighed.

Song Rui's progress is also very good, it took three weeks to develop a special gene repair solution, but this repair solution is for Song Xiaobao's condition, and it may not be suitable for osteogenesis imperfecta that is different from Song Xiaobao's type. But at least Song Xiaobao's problem can be fundamentally solved.

This gene repair solution can repair the gene defects on Song Xiaobao's genome, of course, it is very difficult to completely repair the genomic defects in all the cells of the human body. But in reality, there is no need to repair all the genetic defects in Xiaobao's body. It is enough to repair the genetic defects in the tissues involved in osteogenesis. This is where targeted drug delivery systems come into play. Qin Chuan once again used nanorobots and targeted drugs to treat Song Xiaobao.

On the thirtieth day after Qin Chuan took over Song Xiaobao's treatment, Qin Chuan will undergo surgery to completely treat the root of Song Xiaobao's disease using genetic repair agents.

"The operating room is ready. The patient is in excellent condition. Song Rui said.

"The patient's family has signed. Xiaobao's parents came over. Xiaobao's mood is also very stable. Fang Ping said.

Song Xiaobao's parents learned that Xiaobao was going to undergo surgery to cure the root cause of the disease, so they specially asked for leave and rushed to Tanshan.

"Xiaobao. Be strong. When you get better, Mom and Dad will take you to the park to play. Song Xiaobao's father Song Damin said. Going to the park to play is an extremely ordinary thing for ordinary children, but for Song Xiaobao, it is a luxury.

"When you are discharged from the hospital, your mother will buy you something to eat." Zhang Xiangyu grabbed her son's hand tightly.

Although Han Academy Hospital has already told them that the risk of surgery is not great. But Song Xiaobao's parents are still very nervous. After all, this is an operation that will affect their children for the rest of their lives.

Song Xingben stood aside and just grabbed his grandson's hand and did not speak. He was also very nervous.

Fang Ping walked over: "Don't worry too much about your family, although this operation is very important to Xiaobao, the safety is very high." H&Q has performed thousands of surgeries of the same type and has not had a single accident so far. The treatment techniques we use are very advanced. You can be sure that there won't be any problems. ”

When she arrived at the door of the operating room, Fang Ping hurriedly persuaded the nervous family members.

The more advanced the technology, the lower the technical requirements for doctors. For example, although the operation is large enough to change the genome of a large number of tissue cells in the patient, the operation is extremely simple. As the attending doctor, Qin Chuan didn't even need to do anything, and all the operations were done by his assistant. Various catheters are attached to the patient's body, and nanorobotic doctors carrying targeted drugs are then introduced into the patient's body. The rest of the time is done by the nanobot doctor. Qin Chuan only needed to look at the control screen to judge how the operation was going.

The surgery is not difficult, but it lasts a lot.

Song Damin couldn't sit on the plastic steel chair in the corridor outside the operating room. Song Damin walked back and forth anxiously. Zhang Xiangyu pinched the corners of her clothes tightly. Song Xingben kept chanting the words: Bodhisattva bless, Bodhisattva bless.

"Damin, our son will be fine, right?" Zhang Xiangyu asked worriedly.

"It's going to be fine. Didn't the doctor say it was a very simple operation? Song Damin shook his head vigorously.

"Then why hasn't it come out for so long?" Zhang Xiangyu asked worriedly.

"Didn't Nurse Fang say that the operation uses very advanced technology to repair all the genes in her son's body. Of course, it will take a lot of time. Although Song Damin tried his best to comfort his wife, he was actually very nervous in his heart.

Song Xingben said: "Don't worry, we have to trust the doctor." Dean Qin is very powerful. He took it personally, and there could be no problem. ”

"Yes. I heard that Dean Qin is the boss of Han Academy. He founded such a large group as Han Academy. How could his medical skills be bad? Song Damin nodded forcefully. (To be continued......) r1292

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