"No, no! I don't agree with you! ”

In the office of the director of the Heinz General Hospital Research Institute, Mr. Ehrlich said loudly in an excited high-pitched voice: "You should look at the introduction to immunology written by Mr. Huntelaar and me, to understand the concepts of antigens, antibodies and complement, to observe the agglutination reaction, precipitation reaction and other tests, and you will understand that the elimination of body fluids is the king......

"That can't be!"

Before Ehrlich could finish speaking, Mechnikov shouted with the same excitement!

Of course, it is impossible for Mechnikov to agree with Ehrlich, because since the discovery of the role of phagocytes, he has devoted almost all of his energy and time to it. Even in the face of opposition from almost all of Europe outside of France, Mechnikov never gave up on his ideas.

How can the exponents of cellular immunity succumb to the pioneers of humoral immunity?

"Purr ......"

Leaning comfortably on the couch and listening to the quarrel between the two bulls, John drank the Chinese tea that Ehrlich's secretary had made especially for him, not feeling how unbearable the quarrel was.

This situation, John? Mr. Huntelaar had expected it a long time ago.

In the original history, Mechnikov and Ehrlich were awarded the Nobel Prize in the same year, and the reason for the award was their respective great achievements in the field of immunology. The end of the 19th century was the beginning of immunology, and in the last decade of the 19th century, two schools of thought gradually formed in Europe: the school of cellular immunity and the school of humoral immunity, and the representatives of these two schools were Mechnikov and Ehrlich!

The view of the cell immunology school is very clear, that the body's anti-infection immunity is determined by phagocytic cells in the body; The humoral immunology school believes that antibodies in serum are the main factor of anti-infection immunity. In the last decade of the 19th century, Mechnikov and Ehrlich and their followers were divided into disagreements and arguments. Of course. As with most academic debates, modern immunology is developing at an unprecedented pace in the process of attacking each other......

So, John wasn't in a hurry at all.

The modern medical system is a very complex subject, and immunology is undoubtedly one of the most troublesome subjects for later medical students. In John's memory, when he was studying in his last life, immunology gave him and his classmates a lot of headaches, and the failure rate was second only to a few courses such as biochemistry. This is naturally due to the enormity of immunology itself. Immunology entering the molecular realm in the future is simply too complex; On the other hand, it's because the course is too abstract and not as intuitive as courses like anatomy, histom, and microbiology.

However, no one can deny the importance of immunology in the entire medical system.

Although Mechnikov and Ehrlich are two pioneers of modern immunology that cannot be ignored, their understanding of immunology is too simplistic due to the limitations of the times. However, as a latecomer, John did not intend to forcibly elevate a discipline, and after proposing and refining the concepts of antigens, antibodies and complement, and coming up with research methods such as agglutination reactions, wouldn't it be better to leave the rest of the work to the two immune giants?

"If Mr. Mechnikov is willing to stay. That's for the best. ”

After tasting a cup of coffee, John didn't care about the quarrel between the two big cows, and fell into a fantasy on his own.

If both of them can stay at Heinz Medical School, it will undoubtedly be the most desirable outcome. And for such a character, the collision of academic concepts between each other is even more difficult to find, and with the help of John, a traverser, it is conceivable that this place will become a holy place for immunology for the next ten years or even decades!

And......

If you only look at the surface. The two big bulls seem to be very wrong, and sometimes they even quarrel so much that they blush and have thick necks. It is possible to turn your face at any time, but in the opinion of Mr. Huntelaar, who watched the whole process, this is the best proof that the two of them can work together in the future!

If there is no argument, where can there be progress?

John doesn't know what the relationship between these two immunology giants is in history, after all, although the dispute between cellular immunity and humoral immunity at the end of the 19th century was fierce, John's impression is that it was the last few years. And it's nowhere near as incompatible as Pasteur and Koch. As for the two bigwigs, most of them are because of the Franco-Prussian War. But in this world, John believed that Ehrlich and the two could coexist with each other, otherwise the Russian, who adhered to the concept of cellular immunity, would not have been invited to New York and met John and Ehrlich very happily.

Ultimately. This is also related to the difference in the academic status of the two now.

John? Needless to say, Huntelaar himself has been thoroughly promoted to the top of the surgeon in a few years, and he is also becoming famous in the fields of blood physiology and medicine. As for Ehrlich, he had already invented the dyeing method of white blood cells in his early years, and later invented diphtheria antitoxin serum with John, which became famous; Nowadays, because he worked with Mr. Huntelaar to put forward the basic theory of immunology, it is also the focus of the academic community.

But for the other actor, the situation is not so good.

In this day and age, Robert? Koch's influence is simply too great. The scientists that Mr. Koch criticizes are bound to provoke a swarm of attacks from the majority of the Germans, much like Pasteur in France. So under the protection of Pasteur, although Mechnikov is still conducting his own research and is very tenacious, he still can't twist his arms and thighs after all, and he will have to wait until immunology really develops if he wants to turn over......

There is a huge gap in academic status, how can we fight it?

And on the other hand, John is also confident that he can solve the conflict of ideas between the two. The immunology textbook in his head clearly shows that both cellular immunity and humoral immunity are very one-sided, and at the same time, it is far from representing the huge course of immunology.

It is absolutely impossible for water and fire to be incompatible.

But of course, now is not the time, after all, without the results of the laboratory to prove it, the two bulls will definitely not accept John's statement. So when Ehrlich and Mechnikov finally got tired of arguing, and at the same time looked expectantly at the best arbiter in his heart, John couldn't help but smile bitterly......

……

The academic controversy between Ehrlich and Mechnikov certainly cannot be resolved in a day or two.

According to John's plan, he plans to communicate more with Mechnikov in this month's time, believing that with his "deep" immunology skills, coupled with the top laboratory environment of the school and hospital, at least it will be no problem to make this future face medicine bull excited. Although Pasteur is very famous, John of the Pasteur Institute has been there, and the facilities are like that, and they must not be comparable to New York.

But just as John was thinking about how to keep Mechnikov, two papers he had published not long ago caused a storm without him knowing it...... (To be continued.) )