"Sir, are you looking for me?"

After pushing Mr. Huntelaar's office open, Miss Brown asked with a smile on her face.

She certainly had reason to be excited, because just three days earlier, Miss Brown had been identified as John? Mr. Huntelaar's private secretary. In other words, in the future, he will only have to deal with Mr. Huntelaar's affairs, and he will no longer have to bear a lot of clutter in the office. Of course, what was more important to Miss Brown was not the reduction in workload, but the very act of becoming Mr. Huntelaar's personal secretary!

In Heinz General Hospital, this is one of the most enviable positions.

Although the position of director has been taken by Thomas, it is still Mr. Huntelaar's, and Mr. Huntelaar's personal reputation has skyrocketed in the past two months-his theories and opinions have been cited in countless papers, and the doctors of the hospital have been talking about it lately, and they are quite proud. You know, at the insistence of Mr. Huntelaar, the hospital subscribed to almost all the major medical journals in Europe and North America, which was quite a big expense in this era......

"Well, reply to those letters."

John pushed the stack of letters on the table forward, nodded and smiled: "If you want to study, you can refuse as usual, and I will mark all the academic discussions and hand them over to the corresponding doctors for handling." ”

"Yes, sir."

Thousands picked up the letters, and Miss Brown nodded.

Today, every week Mr. Huntelaar receives a few letters and dozens of letters, mostly from North America and Europe. Most people in North America want to learn surgical sterilization, appendectomy and local anesthesia techniques, and with the frequent publication of those papers in the past two months, the number of people who want to learn basic surgical operation techniques and emergency skills has also increased. As for the letters from Europe, most of them discuss related academic issues, such as surgery. For example, vitamin theory and so on. Of course, John couldn't reply one by one, and basically handed it over to his secretary and Thomas.

She was supposed to leave immediately after picking up the letter, but Miss Brown rolled her eyes and asked with some curiosity, "Sir, aren't you planning to come to the hospital today?" ”

"Haha, I changed my plan for the time being."

John laughed. "Mr. Ehrlich, they have discovered a new sulfonamide drug and invited me to identify it...... And today is the first day of July, so I think it's better for me to come to the hospital. ”

As he spoke, John was in a very happy mood.

He "invented" three sulfonamides, but was still a long way from discovering all the drugs in this family. You must know that the chemists of the future have synthesized a total of tens of thousands of sulfonamides, of which there are dozens or hundreds of them that can be used in clinical practice, so both the research institute in Errich and the research institute in Berlin have never stopped researching in this area. Today, it has finally come to fruition. Two were found in Berlin, and one was found in Ehrlich's research, both of which had a significant inhibitory effect on bacteria.

John is here today primarily to deal with this issue.

Of course, even a time-traveler John could not know the molecular formula of all sulfonamides, after all, in the era when he worked, sulfonamides were not mainstream antimicrobials, and their popularity and practicality were far from being compared to antibiotics. However, it is no problem to help Ehrlich and them develop the appropriate laboratory and clinical trial protocols......

……

In a word, it is necessary to ensure safety before starting human trials."

Once again, the principle of new drugs was reiterated. John said solemnly to Ehrlich: "If the animals do not have serious adverse reactions, start a small clinical trial, and if there is no problem, start to increase the scale of the clinical trial before it can be determined that it can be marketed...... This is a matter of the reputation of our institute, and we must not be sloppy! ”

"I understand, you can rest assured."

Although John's caution was somewhat dismissive. Still, Ehrlich nodded.

Even Western countries, which will pay the most attention to drug safety in the future, will not slowly develop a strict drug testing system until they suffer several big losses after World War II, let alone at the end of the 19th century. Therefore, the rules formulated by John naturally puzzled Ehrlich and others, but they used such things as reputation as a shield. It's okay to accept it.

After nodding with satisfaction, John smiled: "But again, Mr. Ehrlich, these tests with no technical content can be left to others to do, including the continued research of various bacterial antitoxin serums, and if you say, I think you can focus on new directions." ”

It would be a waste to keep repeating the experiment and let Ehrlich do it.

Historically, in order to invent the six-hundred-six, Ehrlich repeated hundreds of experiments, which in John's opinion were completely unnecessary and could be left to students or subordinates to do. For medicine at the end of the 19th century, it was more important to create new theories or new fields, and Ehrlich was the only general in the basic field under John, and he had an even more important arrangement for this gentleman!

"You mean ......"

Ehrlich frowned and asked subconsciously.

"We can start to study the body's self-protection mechanism."

Nodding solemnly, John took out a large brown paper bag from his bag and handed it to Ehrlich: "I define them as the body's immune system, and I have written something roughly, Mr. Ehrlich, you can take a look at it first, and then we will take time to discuss it......"

Studying the immune system is the direction that John set for Ehrlich.

For modern medicine, immunology is a very important branch, especially in the future, artificial immunity not only has a very broad market, but also an important method to eliminate and control infectious diseases. However, at the end of the 19th century, although Pasteur, Koch and others had learned how to prevent infectious diseases with less virulent bacteria, the concept of immunology had not yet been established, and people only relied on experience and other research methods.

What John wanted Ehrlich to do was build this theory.

Of course, this is not an easy task, after all, there was a lack of the establishment and development of a theoretical system before, so John hesitated again and again, and finally wrote this thick stack of "basic textbooks".

This thing is for Ehrlich's "literacy".

It can be said that even if the content of this information is too simple compared to the immunology knowledge learned by secondary vocational nursing students more than 100 years later, for the top scientist of this era, Ehrlich, this major content is complex enough to subvert many of his concepts......

……

Sorry, forgot to inform.

I went back to my hometown in the past two days, and when I went back tonight, I wrote so much before I got on the train. (To be continued.) )