There has never been a more suitable era for the combination of basic and clinical than now.

In the 21st century, the distinction between basic medicine and clinical medicine is increasing, and if the most cutting-edge research results in the laboratory want to be applied in clinical practice, it will take a long time and a huge amount of investment. But at the end of the 19th century, this distance was almost non-existent, and many physicians themselves were basic medical researchers, such as Koch, Bierrot and others.

For John, though, the drawbacks of doing so were well aware.

Lack of focus, or insufficient investment of time and energy is the biggest problem, he still hopes that someone can focus on laboratory research, someone can focus on clinical research, and the two are combined into a relatively efficient small team, which is definitely more efficient than going it alone, and it has been fully proven in the future. As for himself, that's another matter, after all, many basic theories and concepts in the future are at the forefront of research in this era, so it is no problem for him to take care of both......

Two internal medicine physicians, a medical school graduate who is more interested in the laboratory, and a chemist, formed a vitamin research group.

All four of them have received a rigorous German "modern" university education, so naturally there will be no resistance to the combination of clinical and laboratory, and the younger ones are more receptive to John's "wild" imagination, and after a period of training, they should be able to start the study of vitamin theory smoothly. John was so convinced of this that after a small team of four people had formed, he immediately asked Ehrlich to vacate a laboratory with full experimental equipment, and also gave them the first research grant since the opening of Heinz General Hospital: five hundred dollars!

In 1888, this was already a large number.

This money will be used mainly in the laboratory, and in the current experimental conditions. There are no consumables that are too expensive to share, so $500 is enough for them to use for a long time, and the discovery and identification of vitamins cannot be done in a short period of time......

In fact, the establishment of the vitamin theory has been a very complex process in history.

Vitamins were first discovered, also by chance. The 1929 Nobel Laureate in Physiology and Medicine, Aikmann, was a military doctor who began studying beriberi while serving in the Dutch colonies. The disease is more common in Asia and less common in Europe and the United States. Of course, beriberi and athlete's foot are two different concepts, this disease is a neurological symptom or heart failure, and doctors are currently speculating that one is chemical poisoning, and the other is a very fashionable bacterial infection!

The goal of Aikman's research is to discover such bacteria.

The results were certainly dramatic, even if Aikman found out that eating polished rice would cause beriberi. However, when eating brown rice can be cured, future Nobel laureates still believe that there are pathogenic bacteria in polished rice, and that brown rice contains something that can suppress it. It wasn't until a few years later that another person boldly came up with an idea......

Because of John's existence, the vitamin theory appeared twenty years earlier.

However, at the current level of science, it is difficult to isolate and purify vitamins, and it is not easy to accumulate sufficient clinical data. So John set up a group dedicated to vitamins and wrote several papers on the most basic and simple concepts. voted for The Lancet magazine. He believes that with these papers, it will definitely attract the attention of some people. That's enough......

After approving the first research grant and giving the team some "guidance", John quickly focused on the upcoming collaboration with Ehrlich.

The concept of immunology is much better than that of vitamins.

This time, however, John did not need to rely purely on his own "inferences" to convince Ehrlich, as the vitamin theory did. Pasteur and Koch have already established the technology of bacterial isolation and culture, and have also begun to use physical, chemical and biological methods to obtain attropenated vaccines, which can be said to have laid a solid foundation for experimental immunology. What John has to do is to go deeper on these foundations, and slowly put forward the concepts of antibodies, antigens, complement and so on. With the involvement of Ehrlich, an important figure in the history of immunology, I believe that it should not be a big problem to advance the development of this discipline......

……

In addition to outpatient clinics and surgeries, John was busy preparing for his collaboration with Ehrlich, while the family was busy preparing for a big birthday party.

Before you know it, April 17 is coming.

John? Mr. Huntelaar's twentieth birthday, or rather rather his twenty-fourth birthday, had to be done at the behest of old Huntelaar. He hoped to take this opportunity to invite all his old friends and collaborators over, so as to officially put John in the forefront.

Therefore......

“…… I wish John's age was twenty-four! ”

In his living room, old Huntelaar said to everyone with a serious face: "Everyone knows that twenty years old is too young, even if John has made great achievements, but the age of twenty will still make many people feel uneasy, so I hope that at the birthday party the day after tomorrow, everyone will treat him as twenty-four, is it okay?" ”

"Buzz ......"

Hearing old Huntelaar's words, there was a slight commotion in the hall.

Today is two days before John's birthday, and most of the people invited are the friends he made before he went to Europe, Joshua and Funk and others, there are not many of them, but there are more than a dozen. Old Huntelaar's words clearly took them aback.

"Is this necessary, sir?"

Blinking, Funk asked with some puzzlement.

Everyone didn't quite understand what old Huntelaar meant, and only Joshua who had a lot of thoughts and had been in the mall for many years looked thoughtful, pondering the intention of old Huntelaar's move.

"Hehe, let's pay attention to it in the future."

Old Huntelaar didn't explain much, just nodded at everyone and emphasized.

All of them here are John's friends, all of them are his juniors, just explain it, and as for Joshua, their parents will naturally talk about it when they have a chance in the future. Fortunately, John had been in China all the time, and later went to Europe to falsely declare his age. There aren't too many people who need to be notified. People like the people in the hospital thought John was twenty-four years old.

When he had finished his business, old Huntlaar went upstairs.

The atmosphere in the hall suddenly became relaxed, and a group of people hula cheered around today's protagonist John, very curious why he wanted to add four years to himself in one go.

"Really, nothing special."

Facing the questions of friends. John smiled helplessly: "When I went to Europe, I lied about being four years old in order to be able to successfully enter school, so most people I met later thought I was twenty-four years old...... In comparison, you are the only ones who know my real age, so it will always be cheaper to get you to change your words, right? Besides, my grandfather is ready for me to gradually take over the family's property, and being older will make people more down-to-earth after all, isn't it? ”

Although the reason was a little reluctant, everyone slowly accepted it.

Seeing that everyone no longer asks about this topic. John was secretly relieved. For old Huntelaar, it is good that his grandchildren are "older", but for him it is purely about less trouble. After all, people like Thomas and Ehrlich thought that John was twenty-four years old, and if they told them that he was just twenty years old, he would scare a lot of people, right? After all, John was only fourteen years old when he invented the bicycle, and there are so many miracles created over the years, and starting at the age of fourteen and starting at the age of eighteen are two completely different concepts......

Wait until everyone calms down. John quietly pulled Joshua aside and asked in a whisper, "What about Emma?" Why didn't you come again today? ”

"Uh......"

For this question of John. Joshua also looked helpless: "I don't know very well, I originally called her yesterday to come over, but ...... Give her some more time to think about it. ”

Under Joshua's helpless expression, there was a faint hint of complaint.

Emma hadn't been to Huntelaar's house since John confirmed the news that he was really engaged in Europe, how could the two of them not understand the thoughts of such a little girl? It's just that John has always treated Emma as a sister. And Joshua knew this very well, but it was impossible to say that he didn't care at all.

Regardless, Emma is also Joshua's own sister.

Deep down, Joshua still hopes that his sister can be a pair with John, not to mention his sister's thoughts. John's excellence is enough to make the Stone family excited. It's just a pity that they were still young, and when they were older, John went to Europe again, and was taken advantage of by the damned Germans......

Speaking of Emma, both of them looked helpless.

So after a moment of silence, John took the initiative to change the subject: "Joshua, how is the situation at the Flying Pigeon Bicycle Company?" ”

"Not so good!"

Speaking of his company, Joshua's face immediately sank, and he frowned and said: "The price of bicycles has been further reduced to twenty-five dollars a bicycle, but whether it is Europe or North America, there are competitors, and their prices are lower!" So in contrast, the sales of our bicycles this year have only increased slightly, and the net profit has declined...... Alas, John, I now understand why you had to give up your stake in the first place. ”

Compared to the smug look on John's face when he first came back last year, Joshua is full of unhappiness today.

It's hard to keep money out of patents, especially at the end of the 19th century, so Joshua was prepared for it. If it weren't for the comparison of Heinz Pharmaceuticals, he would definitely be very satisfied with the current situation, but seeing that John had dug up another bigger gold mine, it would be impossible to say that he didn't have any other thoughts in his heart.

The price has been decreasing year by year, but the sales growth rate has begun to slow down, which is not a good thing for the flying pigeon bicycle company.

John didn't have a good way to deal with this situation, he could only smile and comfort his friend: "Don't worry, after all, the brand of Feige bicycles was erected relatively early, as long as the quality of your products is guaranteed and the price is not too high, it will definitely continue to maintain a competitive ......."

……

I've been struggling with the age of this protagonist.,This chapter is so decided.。 (To be continued......)