Chapter 30 Vaccines

"Fourteen years, fourteen whole years!"

There was no need for Ehrlich to hide his emotions in front of his old friend, and he said with emotion: "It took us fourteen years to finally cultivate a vaccine that can be used in people...... John, we've finally made it! “

"Congratulations, Paul. Pen | fun | pavilion www. biquge。 info”

Taking a deep breath, John congratulated his friend sincerely.

Fourteen years is a long time for any man, enough for Paul? Ehrlich went from a high-spirited young man to an old man with gray temples. This year, Ehrlich is in his fifties, and the research that began more than a decade ago has finally succeeded.

A new page has been opened in the history of mankind's fight against tuberculosis.

BCG, an artificial tuberculosis vaccine named after two French scientists, was originally supposed to have been developed in 1907 and was officially successful in 1920. But because of John's guidance and Ehrlich's involvement, the world was advanced by a full fourteen years, exactly the same time as Ehrlich's research.

There is no doubt that this is a very long and tedious process.

The highly virulent Bovine Mycobacterium tuberculosis was isolated from cow milk, and then transplanted and cultured on glycerol bovine bile potato medium, and inoculated every two or three weeks for one generation to reduce toxicity, which lasted 14 years and cultured for more than 200 generations, and finally successfully developed a tuberculosis vaccine suitable for humans......

"No, it's supposed to be congratulations!"

Facing John's sincere congratulations, Ehrlich smiled happily: "Without your proposal and research proposal, we would not have been able to complete this great work...... John, if you really have to count it carefully, you are the one who has the most credit! ”

"Haha, you're too modest."

Waving his hand, John laughed and said, "Without your efforts for more than ten years, my proposal would only remain on paper...... Okay, Paul, let's talk about the name of the vaccine. ”

As mentioned earlier, BCG is named after two Frenchmen, but in this world, its inventor has changed, and naturally it is impossible to use this name anymore. So after thinking about it, John decided to hand over the naming rights to Ehrlich.

"Well, it's called the Huntelaar-Ehrlich anti-tuberculosis vaccine."

Ehrlich was obviously prepared, and immediately replied with a smile.

"Uh......"

After listening to Ehrlich's words, John suddenly had a black line in his head: "Paul, your nomenclature is too ...... Well, if you insist, call the Ehrlich-Huntelaar anti-tuberculosis vaccine, put your name in front! ”

Westerners are direct and very fond of naming new inventions or companies after their own names, which John understands decades after his rebirth. But to put his name in front of Ehrlich, he was a little sweaty. He is aware of his own family's affairs, as Ehrlich said, of course, all the plans are proposed by him, but if you want him to be like Ehrlich, bury his head in hard work for more than ten years, it is absolutely impossible! Even Ehrlich himself had a large group of technicians under his hands, otherwise it would be a waste to just do this experiment.

At John's insistence, Ehrlich agreed without saying anything.

After being happy, Ehrlich couldn't wait to say, "John, thirty human experiments have been completed, can you consider publication?" And also...... When will it be available? ”

"Hmm...... I think it can! ”

After pondering for a moment, John nodded and said, "First publish the results, expand the scale of human experiments, and strive to complete at least 300 cases within a year, and then bring them to the market!" ”

Today's Huntelaal system of new drug research has formed a complete system.

First there are laboratory studies, then animal experiments, then small-scale human experiments, then large-scale human experiments, and finally commercial sales. In an age where people can think of hailuoyin as a panacea, this behavior is undoubtedly incomprehensible, including that of most people within Huntelaar Pharmaceuticals.

It is clear that Mr. Huntelaar is giving up a lot of interests.

In most people's minds, it is enough for a new drug to be developed, can be produced on a large scale, and then conduct small-scale medical experiments, and there is no need to delay these steps for a long time. But at John's insistence, Huntelaar Pharmaceuticals, including Huntelaar's hospitals, strictly complied with this rule, even if it was a waste of time and money.

For this system, Ehrlich was actually a little unacceptable, but he knew John's temper better, so he quickly nodded and smiled: "Okay, I'll arrange it immediately......"

Looking at Ehrlich who was hurrying away, John nodded with satisfaction.

Of course, he was well aware of Ehrlich's desire to bring the product to market as quickly as possible, after all, the white terror still loomed over the whole world, and Europe and North America still heard about tuberculosis. Once the historical BCG and today's Ehrlich-Huntelaar anti-tuberculosis vaccine are on the market, it will not only bring huge economic benefits to Huntelaar Pharmaceutical Company, but also bring great prestige to the two!

Koch's example, but it's alive there!

Koch's great achievements in bacteriology were undoubtedly Koch's important contributions to medicine, but it was undoubtedly the discovery of Mycobacterium tuberculosis and the subsequent years of research on tuberculosis. People who have not lived in this era cannot understand the horror of tuberculosis in people's hearts. Not only in economically developed Europe and North America, but also in those backward regions, such as China, until the future of the founding of New China, tuberculosis is one of the three major causes of death of Chinese, killing countless people every year!

But in John's view, no matter how important it is, it is necessary to adhere to principles.

This was not only because some of the concepts in his mind were ingrained, but more importantly, John wanted to establish a rule, a rule that later physicians would have to give a thumbs up. Maybe he can't influence the laws of this era, and he can't influence other pharmaceutical companies, but at least he can do it in his own industry......

Seeing off Errich, John didn't leave right away.

Although he doesn't come to medical school very often these days, he has a lot to attend to every time he does, so after a short break, John dials Professor Osler's office.

However, to John's surprise, after hearing the news of John's visit to the hospital, Professor Osler immediately smiled and said, "Great, John, there is something to discuss with you...... Well, you come straight to my office and have an important guest waiting for you......" (To be continued.) )