Chapter 5 Interested?

Even as a "star chaser", every time he meets a big man who has left a name in history, John has to go and see it for himself. Like Liszt and Koch, John would even go out of his way to travel hundreds of kilometers just to meet real people and have a few words with them.

But at the end of the day, it's just about seeing each other

John wasn't really interested in being friends with them, even if it was just a simple friendship, because he knew that it would be difficult for him and them to coexist with each other. Top figures like Koch and Liszt, both of whom are now successful and have huge prestige, are definitely figures that John avoids. Because John's research is likely to touch their interests, such as Liszt's outdated disinfection technology, or Koch's failed declaration to conquer tuberculosis in the next few years......

But Ehrlich's words are a different concept.

The future Nobel laureate, a leading figure in German medicine, is now in his early thirties, a small associate professor at the University of Berlin and, more crucially, has yet to follow Koch, let alone begin the research that would make him shine. So in front of John, who has already established his academic status, at least the current Ehrlich has no confidence in pride!

So after a few days of hesitation, John decided to reach out to this awesome man who had created an era......

……

“…… So in my opinion, there are still countless unsolved mysteries in the human body! ”

Putting down the wine glass in his hand, John said with emotion: "And I have a hunch that the next few decades or even hundreds of years will be a period of rapid development of medicine, and the new discoveries of our doctors will far exceed the sum of the past thousands of years......

Sitting quietly, Ehrlich listened attentively to the young man in front of him.

Today's dinner was definitely a very special experience for him. Because this Mr. Huntelaar obviously came to discuss his thesis with him, but after the topic lasted less than ten minutes, the conversation between the two quickly spread. From his own new surgical techniques to the latest medical achievements in Europe, from surgery to internal medicine to bacteriology, Mr. Huntelaar amazed Ehrlich like a master of erudition!

"How can there be such a brilliant young man?"

Looking at John's immature face, Ehrlich exclaimed for the first time in his heart.

If what John said was simply broad. Maybe this associate professor won't have too much emotion, but no matter what aspect the other party talks about, he can tell a reason, and he can always make Ehrlich mouth open, which can't help but make people stunned.

"Mr. Ehrlich, do you know much about germs?"

Feeling that the foreshadowing was enough, after taking another sip of red wine, John finally brought the conversation to the main purpose of the day.

"Of course!"

Nodding his head immediately, Ehrlich said proudly: "I am personally quite interested in bacteriology, and I have been following Mr. Koch's research for several years...... Hehe. I have read Mr. Huntelaar's papers on surgical sterilization carefully, and I have to say that your research is very good! ”

"Thank you."

Hehe, John happily responded.

He has heard praise about his research this year countless times, but from Paul? When Ehrlich said it, it was a very different feeling!

"I've heard from my colleagues that the laparotomy you have done now has a high success rate?"

Hesitated. Ehrlich asked, "It is said that all the patients recovered from the open surgery you performed and were discharged from the hospital...... Is that so? ”

When asked this sentence. Ehrlich's expression was expectant.

"It was an appendectomy, and not all of them recovered and were discharged."

After correcting Ehrlich's statement first, John sighed lightly: "In fact, the previous dozens of patients have indeed recovered quite well, and basically recovered smoothly, but only in the past week. Two of our patients died because of the infection that was too severe. ”

"Huh? That's a pity! ”

Ehrlich was slightly stunned, shook his head and said regretfully.

"yes, it's a pity."

Following Ehrlich's words, John said meaningfully: "Although our surgical sterilization technology can minimize the chance of postoperative infection. And it has also achieved very obvious results, but the role of surgical techniques is quite limited for infections that already exist...... It would be nice if there was a drug that would allow us to control the bacteria that cause the infection. ”

Blinking, Ehrlich nodded approvingly.

In fact, not only the two of them, but scientists and physicians who know a little about bacteria, or microorganisms, are looking forward to a drug that can kill or control bacteria in the human body, and countless people are working hard for this.

But alas, the limitations of the times are too strong.

To put it mildly, people have only known about bacteria for 20 years in this era, and people can't even find out who is the culprit for most diseases caused by bacteria! The next 20 years will be the peak era of the development of bacteriology, and the pathogens of various infectious diseases will be found one by one, and if you want to find a way to deal with them, you will have to wait!

Seeing that Ehrlich reacted the same as he expected, John narrowed his eyes slightly, and suddenly said: "Mr. Ehrlich, I plan to conduct research on this aspect recently, but I still lack a companion, I wonder if you are interested?" ”

"Huh?"

After listening to John's words, Ehrlich was stunned.

But before he could ask, John squinted and continued, "I recently stumbled upon a substance that seems to inhibit the growth and reproduction of many bacteria...... I'll call it sulfonamide for the time being, are you interested? ”

……

The so-called sulfonamides, of course, are not a medicine.

In fact, sulfonamides are a general term for a class of drugs, and they all share a common structure of p-aminobenzene sulfonamide. The p-aminobenzene sulfonamide structure was synthesized as early as the early 20th century, but it has not attracted much attention.

After the defeat of World War I, Germany's chemical industry was devastated, and Bayer, which had recovered from the ruins, had lost most of its dye patents and markets, and could only target the pharmaceutical industry. After numerous trials, chemists at Bayer discovered that a red azo dye called Bailangduo was effective in treating streptococcal infections and was overjoyed and immediately launched it on the market.

The impatient Germans did not discover the true secret of the inhibition of bacterial infections.

So driven by the motivation to add to the blockage of the Germans, several cattle people from the Pasteur Institute in France began to ponder the waves, and finally discovered the truly effective ingredient sulfonamide.

The invention of sulfonamides set off a research and development frenzy.

In just over a decade, more than 5,000 sulfonamides were developed around the world, and they were a lifesaver for soldiers in the early days of World War II until the mass production of penicillin......

What John wants to do now is to advance this event fifty years earlier!

Of course, John, who had several classical sulfonamide structures in mind, could actually make them on his own and eventually put them into production in pharmaceutical companies. But after thinking about it for a long time, he decided to try to work with Ehrlich. On the one hand, because this top scientist has a very good character, John is quite relieved, and on the other hand, John also knows that it is impossible to resist everything on his own head, he needs to have a capable collaborator!

Hoffman on the pharmaceutical side was a chemist, and it would have been fine to improve the production process or develop a new product according to John's ideas, but John also needed a really top medical scientist of his time to help him complete his medical theory.

Ehrlich is undoubtedly one of the best candidates.

And John, who knows the life of this great bull, also believes that he must be very interested in the kind of material he is talking about!

Sure enough, under John's expectant gaze, Ehrlich's pupils shrank suddenly after listening to his words, and then a pair of eyes suddenly burst into an extremely brilliant light...... (To be continued......)