After 1885, and by the beginning of 1886, John was ready to officially launch an antipyretic and analgesic drug already named aspirin.

Aspirin, the medicine of the century that still occupies the first place in sales more than 100 years later.

This is an extremely miraculous drug, because it was originally "invented" to treat rheumatoid arthritis, and it was later found that it has a strong antipyretic and analgesic effect, in addition to being anti-inflammatory, can inhibit platelet aggregation, anti-thrombosis, and is used to prevent the onset of cardiovascular and cerebrovascular diseases......

More than 100 years later, scientists continue to discover more of the effects of aspirin.

For humans, this is definitely a very miraculous drug, it is simple to make, but it is so versatile that in the 20th century, Americans even advocated that people should take one tablet a day......

As a stepping stone for John to enter the drug market, aspirin is really suitable.

After the launch of this drug, John is confident that he will be able to promote the name to the world within three years and enter the eyes of all doctors. And this thing itself is also OTC, if the antipyretic and analgesic effect is known to more ordinary people in the future, it is conceivable that the sales will be huge......

At least for this era, it is absolutely unimaginable for ordinary people!

Of course, choosing aspirin as the first shot for pharmaceutical companies has huge benefits, but also huge pitfalls. In fact, in history, there is the famous Aspirin War, and Bayer and other pharmaceutical companies have fought to the death for the dominance of the medicine of the century!

The fundamental reason lies in the patent of acetylsalicylic acid.

In fact, this kind of thing has been synthesized for decades, but it is like many classic drugs such as Bailang and penicillin. Acetylsalicylic acid did not attract people's attention when it was first synthesized, until another Mr. Hoffmann of Bayer introduced it to the market and recommended it to many physicians to use, and its excellent effect on treating rheumatism, antipyretic and analgesic was discovered, thus becoming a gold mountain in the hands of Bayer!

So although John could have chosen another trade name on his own, the strong inertia of his previous life still made him continue to use this unique name.

One of Bayer's ways to deal with the aspirin war in the past life. It is to give the drug a nice and unique name, that is, aspirin, this name under Bayer's powerful propaganda offensive, quickly took root in the hearts of the people, so that people think of antipyretic analgesics as aspirin. With this unique business approach, Bayer eventually gained the largest market share and made aspirin synonymous with acetylsalicylic acid drugs.

So from the very beginning, John didn't plan to let the chemical name acetylsalicylic acid appear!

He just wanted to tell the doctors and the public that the best antipyretic analgesic and antirheumatic drug is aspirin. Aspirin produced by Heinz Pharmaceutical. In this case, even if other companies develop drugs with the same ingredients and launch them on the market in the future, but they have already occupied an absolute head start, John believes that most people will probably only recognize the brand of aspirin, not acetylsalicylic acid......

It was with this intention that John had the confidence to recruit two hundred skilled workers in one go.

In this era, there are no automated assembly lines, and even the use of electric machines has just begun. There are such and such problems, so the production of the factory has to be carried out manually. This is also the reason why the cost of industrial products remains high.

Aspirin production. It's no exception.

That's why John dared to say that the 200 workers were just the beginning, because no one in this era understood the great power of aspirin, the medicine of the century, better than him......

……

The medical device company started construction, the production of aspirin is also in full swing, and the two most important industries of the Huntelaar family in the future are finally gradually taking shape.

When he left Heinz Pharmaceutical, John, who was sitting in the carriage, could finally take his attention off it. put it on his own career as a surgeon.

To be honest, he was very hesitant right now.

As far as his previous accomplishments are concerned, it is clear that surgical sterilization norms have succeeded, and all the physicians at Charlotte Hospital, not just the surgeons, are wearing white coats that symbolize their professional status. Gowns, hats, masks and gloves have become standard equipment for surgeons in the operating room. High-pressure steam disinfection, alcohol disinfection, and iodine tincture are becoming more and more popular, and hospitals and clinics that have accepted the theory of surgical disinfection have been conquered one after another. John believes that the pace of standardization of disinfection technology in the entire world of foreign science will be at least thirty years ahead of his appearance, and with it, the infection rate of patients after surgery will drop significantly, and the mortality rate will naturally be rapidly reduced to an astonishing level.

As for local anesthesia technology, it is now the focus of attention.

For surgeons, safe and effective anesthesia techniques are undoubtedly very attractive, and with the simultaneous publication of John's practical method of procaine and lidocaine in the journals The Lancet and German Medicine, it is conceivable that the two local anesthetic drugs will quickly become popular in powerful university hospitals and become the new favorites of surgeons. As long as Hoffmann and his team develop the technology and methods of industrial production, then surgical anesthesia will truly enter a new era!

A standard of surgical sterilization and the perfection of anesthesia technology will have a revolutionary impact on the entire surgery.

But for John, these are all things of the past.

Because of the limitations of technology and scientific and technological level, John can only go to the point where surgical disinfection can only be done now, advanced concepts such as laminar flow operating rooms are not yet the time to appear, and new inventions such as intravenous general anesthesia drugs are now too advanced and there is no need to appear at all.

Therefore, after perfecting the diagnosis and surgical treatment techniques of acute appendicitis, John suddenly found that if he wanted to continue to move forward in the field of surgery, there were too many shortcomings that needed to be filled!

The most important thing, of course, is the inadequacy of the means of inspection.

There are no MRIs, CTs, or even X-rays, which is a real headache for surgeons who are used to relying on technology. You know, relatively speaking, the signs of acute appendicitis are more obvious, and John is still seventy or eighty percent sure of the diagnosis, but if it is replaced by some other diseases, without the help of laboratory and imaging departments, if the patient's situation is more complicated and the signs are less typical, he will really be numb.

After all, no matter how many years he was born again, John's way of thinking could not have become the same as that of the doctors of this era.

Europe and the United States of this era are not like later generations, where human rights and life are more important than heaven, not to mention the poor, even those rich and even nobles, in the eyes of doctors can be tested. In many cases, top surgeons rely on imagination, speculation, or experience to determine a course of treatment, but that's exactly what John is trying to avoid. The rigorous training he underwent in later generations made it impossible for him to arrange his own surgeries as casually as they did.

So John has been thinking about this question since the end of the academic conference in October.

He could not have relied solely on his own experience and feelings, as other physicians do, and the success rate would not have been high after all, even if John had a later body of knowledge.

"At the very least, we need to get the X-rays out as soon as possible."

After thinking about it for a long time, John finally made up his mind: "In this way, the diagnosis can be a little more confident, and ...... It's time for sulfonamides to appear! ”

Perhaps because of the welfare of the traverser, there has not been a single death of a patient during an appendectomy performed by the Department of Surgery at Charlotte Hospital to this day. However, there have been several cases of severe infections after surgery, and it was only through the full care of the doctors that they could barely be saved. But John knows that this is not a long-term solution after all, even in the 21st century, there is a certain mortality rate from appendicitis, let alone in this era when there are no antibiotics?

"It's time for a revolution in the way clinical diagnosis is made."

Taking a deep breath, John's expression became solemn: "The era of human beings taking the initiative to fight germs is also time to start......

……

It's been so late today.

I have to get up early tomorrow, and I really don't dare to stay up late, but fortunately, it will be easier tomorrow afternoon, so I will try my best to do three more tomorrow. (To be continued......)