After more than a year of rest, the Western Han army was replenished, and Emperor Wu of the Han Dynasty prepared to conquer South Vietnam.

After Lü Jia killed Zhao Xing, he appointed Zhao Jiande, the eldest son born to Zhao Yingqi and his wife of the Nanyue people, as the new king of Nanyue, and sent someone to inform Zhao Guang, the prince of Nanyue, and the officials of the counties and counties under Nanyue. At this time, Han Qianqiu's army entered the territory of Nanyue and captured several border towns. Subsequently, the South Vietnamese pretended not to resist and provided food and drink to allow Han Qianqiu's army to advance smoothly, and when they reached a place 40 miles from Panyu, South Vietnam suddenly sent troops to attack Han Qianqiu's army and wiped them all out. Lü Jia also asked the Han Dynasty envoy to be packed in a wooden box, and attached a letter pretending to apologize to the Han Dynasty, placed it on the Han-Vietnamese border, and at the same time sent troops to defend the various fortresses on the South Vietnamese border. When Emperor Wu of the Han Dynasty learned of this, he was very angry, and on the one hand, he comforted the relatives of the war dead, and on the other hand, issued an edict to send troops to the South Yue Kingdom.

Emperor Wu of the Han Dynasty dispatched 100,000 sinners and sailors south of Jianghuai to attack South Vietnam in five directions. The first road appointed Lu Bode as the general of Fubo, and led his troops down the Huangshui River from Guiyang. The second road appointed the lord Duwei Yang Fu as the general of the Lou boat, and went straight down the river from Yuzhang County through Hengpu Pass. The third and fourth routes appointed Zheng Yan and Tian Jia, two South Vietnamese who had surrendered to the Han Dynasty, to lead their troops from Lingling, respectively, to lead their troops from Lingling, and then Zheng Yan's army went straight down the Li River, and Tian Jia's army went straight to Cangwu. The fifth road is to use the sinners of Bashu and Yelang's army to go straight down to the Kejiang River. However, the Southwest Yi country was reluctant to send troops, and even the monarch of Jilan openly resisted, killing the envoy of the Han Dynasty and the Qianwei county guard. The ultimate goal of the Five Route Army was Panyu, the capital of the South Vietnamese Kingdom. At the same time, Yu Shan, the king of Dongyue, also sent a letter to Emperor Wu of the Han Dynasty to ask for war, and sent 8,000 troops to assist Yang Fu in attacking Nanyue, but when the army of the king of Dongyue reached Jieyang, he stopped advancing under the pretext of encountering wind and waves, and secretly sent envoys to report to Nanyue.

Yang Fu led the elite soldiers, preemptively captured Xunxia, and then broke through the stone gate in the north of Panyu City, captured the warships and grain of the South Yue Kingdom, took the opportunity to advance south, thwarted the vanguard of the South Yue State, and led tens of thousands of troops to wait for Lu Bode's army. Lu Bode led the forgiven sinners on a long journey, and when he joined Yang Servant, he had only reached more than 1,000 people, so he marched together. Yang Fu led the army in front and attacked until Panyu, and Zhao Jiande and Lü Jia were entrenched in the city. Yang Fu chose favorable terrain and stationed his army in the southeast of Panyu, and after dark, Yang Fu led his troops to attack Panyu City and set fire to the city. Lu Bode garrisoned troops in the northwest of the city and sent envoys to recruit the South Vietnamese, who had long heard of Lu Bode's prestige, so they defected to Lu Bode's banner, and at dawn, most of the South Vietnamese defenders in the city had surrendered to Lu Bode. Seeing that the situation was not good, Lü Jia and Zhao Jiande led hundreds of their subordinates to flee before dawn and sailed west along the coast. After inquiring about the surrendered South Vietnamese, Lu Bode learned the whereabouts of Lü Jia and Zhao Jiande, and sent troops to hunt them down. In the end, Zhao Jiande was captured by Lu Bode's lieutenant Sima Suhong, while Lü Jia was captured by Sun Du, the former Nanyue Guolang.

After Lü Jia and Zhao Jiande were captured, all the counties under the Nanyue Kingdom, including Zhao Guang, the king of Cangwu, the prisoner of Guilin County, and Shi Ding, the commander of Jieyang County, surrendered to the Han Dynasty without a fight. The armies of Zheng Yan and Tian Gia, as well as the Yelang army mobilized by He Yi, had not yet arrived, and the South Vietnamese Kingdom had been pacified. In this way, the Nanyue Kingdom founded by Zhao Tuo and the five generations of Nanyue kings were finally wiped out by the Han Dynasty. When the good news of the pacification of Nanyue was transmitted to Emperor Wu of the Han Dynasty, Emperor Wu of the Han Dynasty was on his way to inspect the county of Wushi, so Emperor Wu of the Han Dynasty established Wenxi County in Tongxiang. After Lü Jia was executed by the Han army, his head was presented to Emperor Wu of the Han Dynasty, when Emperor Wu of the Han Dynasty traveled to Xinzhong Township, Ji County, so Emperor Wu of the Han Dynasty established Huojia County in Xinzhong Township. In the same year, Zhao Jiande was also executed, and his head was hung high on the north gate of the Han Dynasty palace. Later, Emperor Wu of the Han Dynasty also set up two counties in Yizhou County, Wangtang and Buwei, and migrated Lü Jia's descendants and clans to prevent the future troubles of South Vietnam. After Emperor Wu of the Han Dynasty pacified the Nanyue Kingdom, he set up the territory of the Nanyue Kingdom into seven counties: Nanhai, Cangwu, Yulin, Hepu, Jiaozhi, Jiuzhen, and Rinan. Yang Fu led his army to cross the sea from Xuwen County, Hepu County, and occupied Hainan Island. The Han Dynasty set it up as Dan'er and Zhuya two counties, and the previous seven counties belonged to the Jiaozhou Thorn History Department.

Emperor Wu of the Han Dynasty was determined to attack the Minyue Kingdom, and he killed Zhang Cheng, a great farmer who retreated to avoid the Minyue army, and Liu Ya, the Marquis of Gushanzhou, for the crime of cowardice, and dispatched the four-way army to besiege the Minyue Kingdom. The first route was led by Yang Fu, out of the martial arts, and entered Fujian from the Chong'an watershed; The second route was led by Han Shuo, the general of Henghai, and made a sentence to attack Dongye by sea by boat; The third route was led by Lieutenant Wang Wenshu, passing through Meiling, and entering western Fujian. The fourth route was led by the Marquis of Yue for Ge Chuan and General Shimose, out of Ruoxi, Baisha, and attacked the northeast of Minyue.

In the face of the Han army's attack, Yu Shan went to Hanyang to supervise the battle and commanded the East Vietnamese army to resist the Han army. He sent the general of the north to guard the martial arts, defeated several captains of the Lou ship army, and killed the commanders. However, the Han army immediately counterattacked, and General Lou Chuan led his army to kill General Beibei, forcing the East Vietnamese army to retreat one after another. Soon, the four Han armies entered the territory of Fujian.

In the unfavorable situation of the battle, Yu Shan commanded the troops to stick to the dangerous Spring Mountain. Wu Yang, the Marquis of Yueyan, who originally stayed in the Han Dynasty, was ordered by the Han court to return to Fujian and persuade Yu Shan to give up resistance, but Yu Shan did not listen. Wu Yang led 700 Benyi soldiers to capture Hanyang City, so that Yu Shan's belly was exposed to the enemy. In the face of the powerful offensive of the Han army, the Minyue aristocracy was divided internally, and Yu Shanshi was alone, so he had to abandon Quanshan and flee back to Yedu.

Emperor Wu of the Han Dynasty sent the general Yang Fu to lead 7,000 troops to cross the Bohai Sea from Qidi, and the right general Xun Yu led 50,000 troops out of Liaodong, attacking Wei's Korea by land and water at the same time, and the right canal sent troops to defend the dangerous terrain. General Zuo took the lead in the attack, but suffered a defeat, and the Han army broke up and retreated to Liaodong. Then Yang Fu led 7,000 sailors to arrive at Wang Wei City, the defenders found that the Han army was not enough in number, and immediately launched an attack, the Han army was defeated and retreated, and Yang Fu fled into the mountains for more than ten days, regathering the scattered troops. General Zuo Xun Yu again attacked the Korean army stationed west of it, but failed to achieve victory.

Emperor Wu of the Han Dynasty saw that the strong attack could not be won, so he sent Weishan as an envoy to Korea to persuade Youqu to surrender with military might. Youqu saw the Han envoy kowtowed and apologized, expressed his willingness to surrender to the Han Dynasty, sent the prince into the Han as a hostage, and sent 15,000 people to escort the prince into the Han, just arrived at the border, the left general Xun Yu, the Han envoy Weishan was afraid of its changes, warned the Korean prince not to bring troops into the country, the Korean prince was afraid, and led the people back.

Emperor Wu of the Han Dynasty saw the failure of the surrender, ordered Xun Yu and Yang Fu to attack again, the left general Xun Yu defeated the Korean defenders in the west of the city, marched to the city of Wangxian, stationed in the north of the city, the general of the boat Yang Fu also arrived at the city of Wangxian, stationed in the south, the Han army attacked for several months and failed to break the city. The left general Xun Yu stormed Wang Xiancheng, and the Koreans privately agreed to surrender to the general of the building boat, Yang Fu, Xun Yu blamed Yang Fu, thinking that he only wanted to make peace and refused to contribute. Emperor Wu of the Han Dynasty sent Gongsun Sui, the former Taishou of Jinan County, to coordinate the relationship between the two armies, and Gongsun then privately conspired with Xun Yu to capture Yang Fu and seize his military power, and handed it over to Xun Yu's command, and the two armies attacked Wang Weicheng again. Gongsun then reported the matter to Emperor Wu of the Han Dynasty, who ordered him to be killed. The Korean minister Nixi Xiangshen sent people to kill Wei Youqu, Kaicheng surrendered, and Wei Manchu Korea perished.