The next day, in the mansion to recuperate for two days, Bailiyan immediately put into the complicated official affairs to deal with the backlog of a large number of official affairs before the history of Li Sinong and Su Neishi, logistics transfer, agricultural restoration and financial appropriation are all priority official duties, the eldest grandson envoy Zhang Jie was not idle all day into the palace to negotiate and ask for an explanation, King Xian prevaricated for various reasons, Bailiyan also simply stayed in the palace overnight and did not return to the house.

On the 19th of August, Baili Yan rushed to the king's family to see Mooney, who had fallen ill with panic from the Xian military weapon last year, and had not recovered until the end of the year, and had fallen ill again shortly after arriving at the Xianling to meet the king, because he had not come for four years, and the tomb had changed again and had become unrecognizable.

At the beginning of this year, Mooney improved slightly, and the merchant group led by him was stationed in Wang's family and listed on the futures market auction center, and the business was quite hot. Starting this year, there will be several large caravans between the north and the south every year, basically ensuring that trade will continue except for the heavy snow in winter.

Through the trade activities between the north and the south, the Jinxuedi people obtained the goods they needed from the Central Plains, and the Central Plains also obtained the goods and precious metals they wanted.

In the near future, the new currency of Xianguo will become the intermediate currency of the North-South trade, which will be directly used for the settlement of trade between the North and the South, reducing the complete dependence of both sides on precious metals, which is undoubtedly good news for Bailiyan.

For the rest of August, Bai Liyan inspected Wangjun, Yongxing, Xuanyun, Wuping, and Ruitian, and asked Ranlan to systematically collect scientific and technological data one by one to build a model.

At the end of August, Bailiyan held a scientific and technological mobilization meeting in Xuanyun to make detailed arrangements for the focus of work in the second half of the year and next year.

"How's the data collection, and how much can be done to optimize the technology in the short term?"

Bai Liyan walked in Xuanyun City and said as she walked, and said in a secret way

"It's not optimistic, judging from the model established by the description provided by Yuke, the biological ability of the axillary people is at least two eras ahead of Yongxing City, and the chance of victory for humans is zero. This is still the result of a simulation based on the fact that the data is not real, and if it is a full data test, I am afraid that the gap will be further widened. ”

The result of the wild calculation is undoubtedly very bad news, Bai Liyan said after a moment of silence with a dark face

"What is the basis of your modeling?"

"Intelligence is ten percentage points higher than that of human beings, physical strength is five times that of human beings, 100 percent of the body's self-healing ability, and the scientific generation difference is less than 30 percent of Xianguo, but the scale of basic industry is 30 times that of human beings. If there is systematic data, I believe this result should be more realistic. ”

"According to you, strong genetically plasmic organisms don't have any weaknesses?"

"Different strong genoplasm organisms have different weaknesses, and the weaknesses in the early and peak stages are more obvious. In the early stage of evolution, it is inevitable that there are weaknesses in the core solver, and in the later peak, because the potential of the core solver is close to the limit, and the civilization is still growing, the biomass weakness will be constantly exposed due to the gap in civilization and the depletion of potential.

Therefore, most of the strong genetically advanced organisms have exhausted their potential due to the rapid evolution in the early stage, and because they rely too much on genetic evolution to replace the actual physical science, while ignoring the development of science and technology, the development momentum in the later stage is seriously insufficient, but the early stage is still quite terrible. ”

"In other words, the weakness of the early state of strong genetic organisms is more obvious than that of current human beings and can be eliminated."

"Theoretically, this is true, but if this targeted measure is used for a long time, they will quickly eliminate this weakness through genetic mutations in the next generation, or even two or three generations later, so if they cannot be controlled and reconciled in a short time, it also means that they will become stronger in a short period of time after being stimulated.

Moreover, the development of civilization is full of accidents and references, once your technology is acquired by them, they can quickly copy it if there is not much difference in industrial capacity and technological level.

Therefore, you have automated weapons, and if they capture them, there is a high probability that they can be copied. And according to the information provided by the Imperial Guest, there are highly intelligent dwarves among the armpit people, which means that the probability of being copied after obtaining technology is higher. ”

Bailiyan held his forehead, his head ached, he rubbed his face and calmed down for a moment, and then he asked

"What kind of technical advice can you provide?"

"In my opinion, you have developed to today's level in more than 20 years, and you have almost taken the right 85% shortcut to development, and you are already remarkable."

"I don't need you to compliment me, I want to rationalize the proposal."

"Well, first of all, you have to recognize the reality that no matter how you increase your industrial scientific and technological capabilities now, the scale of basic industry is not large enough, the industrial population is not large enough, and you cannot complete the overwhelm in quantity and quality, and you cannot solve the problem of armpit people in the short term.

Therefore, in a relatively long period of time, you, or this regime, must do two things, one is to rapidly increase the population and education, and the other is to accumulate scientific research, accumulate the scale of the population of basic industry, pile up the scale of basic industry, and increase the density of high-level human resources in society. For some time to come, you will have to choose to offset the slaughter of the Armpits with population losses.

After my analysis, now I can only give you six points of help. First, under the limit that can be achieved by the current industrial processing, the design of the train locomotive and the diesel multi-cylinder engine that has been finalized by technology should be optimized to the greatest extent, so as to make the structure more reasonable, energy-saving and more efficient.

Second, the design of power installations and energy production units should be optimized to the greatest extent possible, also based on existing industrial capabilities. Third, the benefits of accelerating drug development are many. ”

"The physiological function of axillary people is strong, and there is no hope for human beings to survive under a blow, why accelerate drug research and development, and the benefits will be more?"

"You should know that the progress of medicine is an important measure to improve the quality of the population and increase the population base, and the research and development of drugs and medical technology is to increase the population, improve the quality, and indirectly provide certain treatment to the army and avoid more casualties.

Secondly, as a doctor, you should know that the research and development methods of early chemicals, animal and plant drugs, and microbial extracts are similar, and what really promotes the acceleration of drug research and development is the improvement of equipment and the emergence of central computers.

Even when there are new manufacturing processes, it is more about manufacturing processes and efficiency that are improved, and the basic methods are rarely changed. Therefore, before the galactic civilization, the basic principles of drug research and development did not change much. ”

"And then?"

"With the current conditions, human medicine is the most developed compared to other sciences, and at the same time, with the help of cargo ship equipment, the conditions for the production of bacteriogens are already available."

"Bacteriogen? What is this thing, the definition of your new editor? ”

"It is a future drug defined by the noun I edited according to the logic of your knowledge language, and this drug will be used as a long-term medical drug in the future."

"How do you get it, and what conditions do you need?"

"It's actually very simple, you know that using antibiotics can suppress bacteria, and you should also know that bacteria will mutate and become stronger after exposure to high doses of antibiotics, right?"

"Yes, Guardian No. 1 has just appeared for four months, and mutated drug-resistant bacteria have been found in the laboratory, which is a difficult problem that has to be faced after the development of antibiotics.

"Yes, depending on the variety, under the action of high concentrations of bacteriogens, the probability of mutation is only 1 in 20,000 to 1 in 400,000 of antibiotics, and it is possible to use mutated bacteria to extract effective bacteriogens.

In short, any superbug on its own can be used to produce a bacterinogen, with far fewer side effects. ”

"Such a good thing, can be extracted right now? Why hasn't Earth Technology been discovered? ”

"Because it is precisely the antibiotics that are neutralized and even eliminated by antibiotics, you will always only get antibiotics. Dysenterin is a small molecule component attached to the cell wall, when the cell is in the normal state, the density of this component is not high, when it encounters external erosion attack, the cell will accelerate the production of mycogen, to resist external invasion.

Antibiotics are the secretions of microorganisms, and the main principle of inhibiting bacteria and killing bacteria is to attack the cell wall tissue, prevent the cell wall from healing, or attack the genetic components to stop their replication and proliferation, or perhaps use the gluttony of the cell to support it.

All in all, no matter which way the antibiotic mode is, it stimulates the cell itself, so antibiotics are not only destructive to harmful bacteria, but also to human organ cells.

In the event of external invasion, including antibiotic invasion, the sensensin will neutralize the attack of external substances on the cell body. ”

"Since it is a defense substance secreted by cells, what is the principle of action of bacteriogen-killing of bacteriogen?"

"Using the characteristics of good affinity of bacteriosensin components, the cell wall and genetic material are deceived, so that they attach to or even penetrate into the target cell wall and integrate into the cell wall, causing them to deteriorate. Finally, the cell wall is broken or encased, making it unable to proliferate and divide. ”

"That is, put a bunch of spies in there, and then interfere with the work of cellular autoimmunity."

"Yes, when the cell is not attacked, the secretion of bacterogenin per unit time is limited, once this amount is exceeded, the cell will no longer continue to secrete, but the mycomensin is still increasing, and finally it will harm the target cell itself.

However, like antibiotics, according to the different ingredients, different sensembles also have broad-spectrum antibacterial and narrow-spectrum antibacterial, and the production of bacteriogens is easier than antibiotics, but the premise is that this conceptual field must be recognized, and scientific research and production technology conditions must be met.

Due to the process of bacterial destruction by antibiotics, the small molecules of sensin are not easily observed by electron microscopy and other advanced observation methods, and are neutralized by antibiotics at the same time, so they cannot be identified in the early stage. ”

"What about the side effects of such a good medicine?"

"It depends on the screening of the bacterin, because the affinity of the inogenin is very good, so as long as the cells that secrete the biogenin are similar, they all have the same molecule of the biogenin, so if the biogenin is similar to some or most of the cells of the human body, it will cause harm to the human body, and vice versa.

Therefore, as long as the screening is done properly, there will be no side effects, and if the conditions are relaxed a little, the side effects are equivalent to 1/15 to 1/200% of antibiotics, and some have no side effects. ”

"How to make extraction, and how to achieve it with current technical means?"

"By adding chemicals, microorganisms, antibiotics, etc., bacteria are stimulated to secrete bacterioreceptors to resist invasion, and at the same time, they are separated by inverter microelectric shock at medium temperature, and then centrifugal filtration extracts the active ingredients."

"It's as simple as that?"

Bai Liyan questioned, but Wild Lan said

"The principle is very simple, but the extraction of bacterogens lies in frequency conversion discharge and frequency conversion temperature change, which prompts the mycosgens to strip off the cell wall, and different mycosin has different requirements for the frequency conversion frequency and the periodic amplitude, so it is no exaggeration to say that each bacterogen, requires different frequency conversion electric shock and temperature change frequency.

A major mutation of the same bacterium requires another change in frequency, and repetition rarely occurs. In short, each extraction of a protosphin requires a complete set of encrypted telegram ciphers, and the time taken to decipher this set of codes varies according to the difference in computing power.

Therefore, even if the earth civilization discovers the bacteriogen, there is no possibility of extracting it in the short term, and the cost of extraction in a small number of laboratories is very high, so it is difficult to produce it industrially until the technology is mature. ”

"So you have the computing power and microbial testing equipment, so you can speed up the production and extraction, am I right?"

"That's right, but you still need to make some auxiliary equipment and equipment to make it. In addition, the microbiota needs to be screened for long-term culture, which may take a cycle. ”

"How long?"

"It depends on demand. There is no obstacle to cracking the extraction frequency now, what is the obstacle is your supporting facilities, auxiliary microbial screening and multiplication culture, as well as long-term observation of human biological properties. ”

"Well, I'll implement the project as soon as possible and start research and production as soon as possible. Also, does antibiotic research need to be stopped? ”

"No, you don't. In addition, antibiotics, animal and plant cytoplasm, animal and plant stem cells, and protease-guided transformation will be used in the future to synthesize cytosolic enzymes, which is a more advanced drug with few side effects, but it is not possible to obtain it for a long time at present and in the future. ”

Cytosolic enzyme is another more advanced semi-biological drug, which has become an important medical drug for a long time in the future together with bacteriogen.

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