Downing's philanthropic reputation is unassuming, and this is reflected in many of his details, such as the formula of rehydration salts for cholera, which he has made available to the world through Guò Nature, and said that it is not patentable and can be used in all hospitals. He also worked specifically with St. George's Hospital, which has a large number of beds, to observe the effectiveness.

When he visited St. George's Hospital, he was frightened by the surgical scene at that time, with black axes and forks as tools, and began to make patients without even sterilizing procedures, which was like a slaughterhouse.

He decided on the spot that he should immediately invent more advanced scalpels, anesthetics, and disinfection methods, otherwise he would come to this world in vain.

In the case of incomplete chemical industry, there are many chemicals that rely on biological extraction for production. The local anesthetic that Downing wanted to invent was lidocaine. Generally, it takes effect after 1 to 3 minutes of application, and the effect lasts for 1 to 3 hours. It is a derivative of cocaine, which is extracted from the coca leaf and then chemically transformed into a final product.

If nothing else, humans will be the first to invent the widespread disinfectant phenol in a few decades, but this chemical is irritating, corrosive and toxic to the human body. Alcohol and iodine are ideal methods of disinfection.

The biggest trouble in medical research comes from animal and clinical research, which will be quite expensive work, but fortunately, Tang Ning is a big tyrant, and the huge consumption in the eyes of others is not worth mentioning in his eyes. Under his management, the world's largest animal farm is under construction, which will raise a large number of melanogasters, mice, rats, rhesus monkeys, and chimpanzees.

Drosophila is a fairly economical small animal, and it has a wide range, roughly overlapping with that of humans. It reproduces once every 14 days, lays 400 eggs at a time, and hatches within 22 hours at a suitable temperature of 25 degrees, according to the sentimental saying of one scientist, "half a bottle of milk and a banana that is starting to rot is enough, and 200 fruit flies can be obtained in 14 days".

Mice and rats are mammals that are very similar to the human digestive tract, and most of the genes are the same as humans, of course, the most similar to human genes is the close relative of human chimpanzees, more than 99% of the genes are the same, and can be regarded as the ultimate animal before clinical practice.

Rhesus macaques are an economical and large primate that is easier to keep than chimpanzees.

The inaugural issue of Nature was an instant hit, and the most talked-about thing is that its blockbuster scientific paper proved the theory of the three primary colors in its own printing method without dispute, and also overcame the heavy engineering difficulties of using color in photography and printing in one fell swoop. After the inaugural issue was given away for free, word spread, and scientific and engineering enthusiasts and amateurs rushed to the "Nature Bookstore" next to the East India Building in St. James's Square to buy them.

Nature's success has boosted hospitals' confidence in cholera theory, and since the release of the formula, hospitals have announced that their clinical results are in line with Downing's expectations, and that St. George's Hospital has announced the great news of helping to alleviate cholera earlier than St. George's Hospital. At this time, although there was no major outbreak in London, it was happening all over the world, especially on ships with wars and harsh conditions.

The success of the cholera theory further boosted the confidence of the industry in Downing's disinfection theory, and the April issue of Nature disinfection theory was officially released, mainly introducing the use of alcohol, iodine and high-temperature steam in disinfection. In a conversation with doctors at St. George's Hospital, Downing learned that the reason why surgery was not sterilized in this era was because of the "theory of natural generation". This theory holds that diseases occur naturally, and that the meat and plants of ** naturally breed diseases. Of course, this is wrong, Downing designed a broth cooked at high temperature and placed in two environments, one in a vacuum environment and the other in an open environment, and as a result, microorganisms appeared in the open environment for three days, but the broth in the vacuum environment was always clear and clean. This practice strongly refutes the theory of spontaneous generation and lays a solid foundation for the theory of disinfection. It would take a long time for ordinary scientists to make such research for medical applications, but Downing's prestige was now in full swing, and soon major hospitals in London were buying real drugs from his "Windsor Medical Device Factory" to test his theory of microbial pathology.

By May, Nature magazine is like the flowering season, with dolicaine anesthetics proudly produced, a highly effective local anesthetic that lasts for hours in just two or three minutes. In his paper, Downing said that the anesthetic had no major side effects after preliminary animal practice. Fellows are welcome to his "real yàn zoo" to buy animals to make real yàn. It was in this issue of Nature that Downing elaborated on the addictive properties of morphine, the core ingredient of opium, and proposed laws restricting the medicinal use of opium, calling it "an anesthetic, a semblance of symptom relief, not a cure", and that opium should not be used as a drug unless absolutely necessary. As a shareholder of the East India Company, a great opium dealer, these words only proved his public intentions. Lionel, who held a large number of shares in the East India Company, was furious.

Downing didn't care about the huge controversy he had provoked, and now his fame was enough to rival the Rothschild financial empire, at least not to be suppressed. Queen Victoria, the Chancellor of the Exchequer, and Scottish bankers all hold a lot of shares in British steel mills, making the power of Downing the core of the interest group not to be underestimated. Scotland's financial industry is quite developed, the world's earliest insurance company came from Scotland, because it is connected to the boundless North Atlantic Ocean in the north, the wind and waves are bad, and the sea god swallowed too many fishing boats, so the Scots set up a pension fund for widows, which is the earliest insurance. Later, Scottish bankers fought with Rothschild for control of the East India Company for a long time.

Rawlinson saw the Telegraph report in Melbourne, slapped the table, and said, "Good boy, I really did it to my old club!" Rawlinson, on the ship from India to London, had heard Downing speak of the dangers of opium. Incredibly, Downing did not sell the shares of the East India Company in advance when he issued the opium restriction warning. He wanted to throw it away, but the one-year time limit had not yet arrived.

Sure enough, the Times reported on the opium danger in a big way, and the East India stock fell sharply, which was a precursor to the possibility of restricting opium, and now Downing's reputation in the scientific community was too high.

Of course, it is impossible to underestimate the energy of the shareholders of the East India Company, and the press that used to be one-sided and say good things about Downing finally began to have a lot of negative news, and even some of it was very powerful, for example, someone dug up the MIT of Downing's graduation, and there was no Zài in Massachusetts, USA! The most powerful scientist in Britain is actually an academic liar! It was also the biggest blow to Downing since the telegraph was connected to the world. If it weren't for the convenience of this communication, who would have the time to check the mit?

Even more powerful in the back, someone deduced from his appearance that he was Chinese! And evilly thinks that his international school park plan is for China at all, because only China is the largest in the world in terms of population ratio, and the international school park is actually a base camp for Chinese students. Ho, this has not yet begun, and it has been picked up, and the British media is really powerful.

Free speech is really powerful in limiting one's ability to control a large number of resources, and because of the storage of a lot of negative news, his plans for great medical progress have been blocked, and many hospitals that had been eager to try it have been deterred, believing that Downing may be the great deception of the century.

Then, the plan to reserve heating, electricity, and methanol pipes in the sewer plan was also exposed, and Congress asked Downing to be questioned by lawmakers.

This is exactly the meaning of the question of the democratic and liberal system, Downing was not angry, and calmly went to Parliament to make a speech, defending his sewer plan, saying that he had obtained the consent of all the members of the Sewerage Committee, and that it was for the orderly development of underground pipes in the future, in order to avoid suspicion, he would resign as chairman of the committee, concentrate on the research and development of sewage treatment plants, and said that he was making a number of sewage treatment demonstration models, which would be distributed to the most populous cities in the United Kingdom. It provides a reference for city governments to formulate sewage treatment plans. (http：／／.）。

Some lawmakers actually asked, "What's the deal with MIT?" I've asked a lot of people of great repute in the United States, and there is no such school or university in the whole of America. ”

Downing said lightly: "The abbreviation MIT is indeed a bit problematic, you can see it as me putting gold on the face of my alma mater, it is just an ordinary technical school in Massachusetts, with only a dozen students, and the name MIT is of course boastful, and not many people know about this abbreviation." I'm very sorry, but I do suspect that I am misleading the masses. ”

In addition to his own telegraph, even the well-connected daily news reported on the great inventor, physicist, chemist, and microbiologist Baron Buckingham boasted of a small school with a dozen students as MIT, laughing to death!

None of this was a big deal, but one of the things he valued the most: becoming governor of the Straits Settlements, was also affected, and a congressman asked Downing "Is it true that he has Chinese ancestry?" ”

Downing still said lightly: "I don't know! I was surprised to have such a rumor and went home and looked in the mirror, eh? It's a bit like, maybe they're telling the truth, but alas, I can't ask my poor parents who died in the shipwreck. ”

There is no right symptom, this hand is very clever, but the influence is still there, because he is worried that becoming the governor of the Straits Settlements will affect his fairness in dealing with local ethnic relations, this important position is in vain!

This is the biggest setback Downing has suffered since coming to this world, which means that he will return to his homeland, and the big springboard Singapore will not be able to go in the near future.