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[230] Four new drugs

When Hu Guang appeared near Beiying, Nie Feng, the investigator in charge of tracking Hu Guang's whereabouts, faintly felt something wrong in his heart.

According to the information provided by Xiaoqiang, the Ministry of Intelligence completed the arrest of all important hidden agents in the northern capital in the early stage. In the deployment of the Ministry of Intelligence, the gangster named Dysentery was deliberately let go as a fishing bait, so that in the future, he could immediately discover the new leader sent by the Kuomintang secret service to the northern capital.

Hu Guang went all the way north cautiously, but he couldn't count it, he had just connected with the kid with dysentery, and he had already been discovered by the General Intelligence Department of the army.

After Nie Feng, an investigator of the Intelligence Department, completed the previous leak case of Hu Fan and Yang Yuan against Su, he was immediately transferred and was responsible for 24-hour monitoring of Hu Guang together with investigator Li Tang.

Nie Feng was watching Hu Guang in a small grocery store in the distance, racking his brains and thinking, he didn't understand that Weishenme himself would be so sensitive to Beiying Studio.

"No, there must be something wrong here! Hu Guang must have come here to connect with people, but what is the matter with this ominous premonition of mine? Is there anything unusual about Beijing Film Studio? ”

Nie Feng couldn't figure it out after thinking about it, so he opened his mouth and whispered to Li Tang beside him, "Do you think something is wrong here?" ”

Li Tang and Nie Feng together, the two hid in this small grocery store and pretended to smoke and chat, and said suspiciously: "Isn't it Beiying Studio, is this Hu Guang's connector an actor?" ”

As soon as Nie Feng heard Li Tang's words, there was a loud alarm in his mind, and he said with wide eyes: "There is an actress here, who has been to Willow Hutong before, do you remember?" ”

Li Tang saw that Nie Feng's face had changed greatly, and he was also surprised: "There is an actress who has been to Willow Hutong, isn't it?" ”

The willow alley where Xiaoqiang lives is currently inhabited by some important leaders of the organs under the Central Committee, and there are also leaders of the headquarters of the General Intelligence Department of the Army, including Minister Li, Nie Shuai and others, and Xiaoqiang, as Minister Li's neighbor, also lives here. Therefore, Liushu Hutong, as the key protection object of the Central Security Section, looks loose on the outside, but in fact it is strict on the inside, and it is very closely guarded.

Nie Feng's memory is very amazing, and he still remembers that he had seen such a message on the tracking questionnaire of people entering and leaving Willow Hutong before, XXX, an actor from Beijing Film Studio. Of course, these investigations were conducted in secret. As a scout who, like Li Tang, had worked in the Central Security Section of Section Chief Cao Chunzhi, Nie Feng suddenly recalled at this moment.

Nie Feng frowned and said, "I can't remember the name." ”

Li Tang lightly touched Nie Feng with the elbow of his right hand smoking: "Don't think about it, you see." ”

Nie Feng followed Li Tang's gaze and looked into the distance, and happened to see the scene of Hu Guang talking to Meng Sisi.

Nie Feng's heart tightened, and he said anxiously: "You must notify the ministry immediately." ”

Pu Hai,

East China People's Pharmaceutical Company,

Penicillin Laboratory,

The director, Tong Village, is inspecting the petri dish for penicillium one by one.

"Director, with this corn syrup production line, the survival rate and density of our bacteria have greatly increased!"

"Yes, Director, this corn syrup production line is so good! In addition to corn syrup, the corn starch produced can also be used in other medicines. ”

Tong Cun smiled and nodded: "It's really good, there are these new process materials for producing penicillin and these centrally allocated equipment, I think as long as next month, we can officially put into production and trial produce the first batch of penicillin." ”

After saying that, Tong Village's eyes couldn't help but blur.

Since 1946, Tong Cun has been experimenting with penicillin in the North Plains Department of Health Laboratory using yellow penicillin strains in three glass tubes brought back from the United States in 1944 by Dr. Fan Qingsheng, a doctor who studied in the United States. Due to the pitiful amount of funding for the Kuomintang's scientific research, the progress of the institute's trial production was extremely slow.

Historically, it was not until after the founding of the People's Republic of China that Tongcun successfully trial-produced the first batch of crystalline penicillin samples on September 6, 1950.

Now, with the various pharmaceutical factory equipment and medical research experimental instruments brought back by Xiaoqiang, the penicillin laboratory has completed the laboratory manufacturing of the first batch of crystallized penicillin in March 1950.

In accordance with the secret information given by the central government, Tongcun has continuously expanded the scale of the laboratory, and has now begun to develop penicillin, streptomycin, oxytetracycline, tetracycline, chlortetracycline, synthromycin, chloramphenicol, gentamicin, kanamycin, erythromycin, but at present, the researchers are very tight, and every scientific researcher is working overtime in a row.

Tong Cun took off his glasses, rubbed his eyes that shed tears because of fatigue or excitement, and said: "At present, these are the most advanced antibiotics that we need to research and produce, even the West is only in the laboratory stage, and has not been able to produce them industrially, and there are some drugs that the West has not studied at all, such as cephalosporins and other drugs, I am sure that as long as they are produced, they will be sold all over the world." ”

The researchers around them looked excited and nodded vigorously, for them scientific researchers, as long as the funds are sufficient, the equipment is complete, and the scientific research environment is good, then they really don't care about anything.

"Director, these materials are said to be the most advanced, and the manufacturing cost is much lower than that of foreigners. But where are the 491 Engineering Pharmaceutical Research Institute and the 491 Engineering Medical Equipment Group? I really want to see it with my own eyes and open my eyes. One of the researchers looked at it with a wistful look on his face.

Tong Cun's heart is also full of curiosity about this 491 Project Medical Research Institute, how did the geniuses there come up with these solutions and manufacture such sophisticated equipment, weishenme They do not produce their own but transfer the research results to the Puhai Penicillin Laboratory? The superior leaders said that our Puhai Penicillin Laboratory is an incubation base, and it will be renamed Puhai Pharmaceutical Research Institute in the future. At present, our laboratory only needs to digest and absorb the research results, data and data of those geniuses, and then master the operation of these amazing production equipment. Those geniuses of Project 491 don't have time to do such meticulous work, they seem to be born to create, and they are not interested in follow-up research and technology incubation and production.

"But they've done all the most important work." Tong Cun shook his head, sighed, and said to himself in his heart.

"I also hope to be able to go there one day and see it myself." Tong Cun replied.

With the increasing variety of drugs brought by Xiaoqiang, the disease cure rate and hospital administration rate in New China are rising. The rising cost of medicine has also begun to attract the attention of the central government, although the price of drugs brought by Xiaoqiang is as low as a free gift, but the work of opening up and increasing income must be more promoted. So at Xiaoqiang's suggestion, a larger-scale drug export began.

Hong Kong in 1950.

Huo Yingdong's penicillin business was already booming at this time, and what made him even more excited was that someone came from the north and asked him to start preparing a batch of new drugs.

Among them is streptomycin, which is used to treat tuberculosis.

Compared to penicillin, which was discovered in 1928, streptomycin was only discovered by American scientists in 1943, and large-scale industrial production did not begin until the mid-50s. New China is selling this product on a large scale at the moment, and it is completely scorpion on shijie - the only one!

Fok Yingdong has seen many tuberculosis patients, and doctors generally use penicillin to treat them, but the effect is not very good, but only this method can barely be used. This method of treating tuberculosis with penicillin, which was an informal treatment in 2011, is extremely ineffective and has a very high mortality rate, even if the amount of penicillin is increased several times, less than 30% of tuberculosis patients can be revived with penicillin.

There is also chlortetracycline in this batch of new drugs.

It was only discovered in 1945 by scientists extracting a species of Streptomyces aureus from soil samples, and was mainly used for penicillin-resistant bacterial infections. As the price of penicillin has been beaten into the price of cabbage by New China, and the global consumption continues to rise, it is believed that it will not be long before bacteria that have developed resistance to penicillin will appear. Historically, chlortetracycline was not used in large-scale industrial production on shijie until the end of the 50s.

There are also soft plastic vials of chloramphenicol eye drops. Chloramphenicol is an antibiotic extracted from Streptomyces venezuela in 1947, and it is also the first broad-spectrum antibiotic made by a completely industrially synthetic method on shijie, the price is extremely low, but its side effects are prominent, it may cause aplastic anemia, shijie countries have rarely used, but continue to be used as topical eye drops. Chloramphenicol eye drops are inexpensive and very effective in treating bacterial infectious diseases of the eye.

Zuihou is oxytetracycline, and the structure of this broad-spectrum antibiotic was only figured out in the West in 1953, and it was not until the end of the 50s that it could be mass-produced. This antibiotic is specific for intracellular infections, and for some diseases caused by intracellular infections, the treatment effect is better than other antibiotics.

How much profit can be made by the four new miracle drugs? It's exciting to think about. Huo Yingdong is gearing up to invest in the new business.

Fok Yingdong registered a company Starlight Pharmaceutical and began to apply for patent protection for the above four drugs in all countries with patent law systems. However, the central government did not place much hope on these four drug patents, after all, these are already antibiotics that have been researched on shijie, but they have not yet moved from the laboratory to industrial production, and it is really whimsical to say that Western countries will recognize your patents.

For Huo Yingdong, the most important task at present is to use his channel advantages to continue to dump and distribute goods to foreign countries.

At this time, the drug smuggling trade between Hong Kong and the mainland had entered a new peak, and ships came and went between Shenzhen and Hong Kong every day.

In the headquarters building that Starlight has just bought at 17 Queen's Road, a tender for agency rights is underway.

"Mr. Huo, I want to be in charge of the agency in France."

"Mr. Huo, I hope to obtain the right to represent Italy."

"Mr. Huo, our sales channels in Brazil are very complete, and we hope to get the right to act as a drug agent in Brazil."

…………

Looking at these excited commercial firms, Huo Yingdong's face was full of smiles, and the only proprietary drug meant a monopoly. All the bosses here are well aware of how profitable the monopoly is.