Chapter 271 Penicillin

The reason why Wang Bin returned to Fengtian in such a hurry was because there was a scientific and technological achievement in Fengtian that would shock the world to appear in this world. Pen & Fun & Pavilion www.biquge.info

And this scientific and technological achievement is antibiotics, and the only antibiotic that Wang Bin can prepare in this era is penicillin.

Penicillin is a widely used antimicrobial drug, which is inherently less toxic, but more commonly allergic to the drug, causing adverse reactions and death.

The antibacterial effect of penicillin is even better, it can be antibacterial at low concentrations, and it can directly kill bacteria at high concentrations.

Streptococcus, pneumoniae and other gram-staining positive cocci have a good effect, and also have an effect on sensitive staphylococcus, meningococci, gonorrhoea and other Gram-negative cocci such as meningococci, as well as diphtheria, tetanus bacilli and other Gram-staining positive bacilli and spirochetes.

It can be said that in this era, penicillin was enough to be called a miracle drug, and it was used to treat many terminal diseases that were considered incurable at the time.

As early as after Wang Bin brought Wu Liandra under his command, Wu Liande found several domestic medical scientists for Wang Bin through his own connections to establish a complete medical system for Wang Bin.

In particular, on the issue of treating the wounded, these medical scientists proposed the method of using concentrated salt water to clean the wound after the wounded came down from the firing line, which can reduce the infection of the wound to a certain extent.

You must know that in this era when there are no antibiotics, once the wound is infected, your life is basically left to fate, unless you are favored by God, you can be saved from the wound infection, and the rest of the people are basically dead.

In this era when there are no antibiotics, once you are infected, you can only watch your wounds continue to suppurate, and then gradually lose your life.

And the soldiers have always had a high mortality rate because of wound infection, and Wang Bin has been forgetting about it because he is busy, until finally Wu Liande and others proposed to Wang Bin to clean the wound with concentrated salt water, which reminded Wang Bin of the matter of antibiotics.

The simple preparation of antibiotics still has a little image in Wang Bin's mind, but it takes time to recall and perfect.

During the period of time recalled by Wang Bin, Wu Liande and others proposed the practice of using concentrated salt water to clean the wound at the first time of injury, which effectively reduced the infection caused by the injury of some soldiers in the Sino-Japanese War.

During this time, Wang Bin also officially began the simple preparation of penicillin.

The simple preparation of penicillin is relatively simple, but for Wang Bin, an unemployed vagrant who graduated from the Department of Biology before the crossing, the preparation of penicillin is just a piece of cake.

Even the professionals of this era can do it with a little pluck, but the main thing is that they don't know that penicillium can be extracted at a certain concentration after fermentation.

And no one has noticed penicillin, even if it's been more than a decade since Fleming noticed the effects of penicillin.

Speaking of which, preparation is actually a relatively simple process.

First, a large amount of penicillium is collected, cultured with a nutrient solution, and then the culture is filtered, canola oil is added and stirred. Stir and remove the water.

Most of these non-refractory substances and lipid-tolerant substances are removed by the above methods.

Subsequently, the charcoal is ground into a powder and the culture medium is added to allow the charcoal to fully absorb penicillin.

The charcoal that has absorbed penicillin is then placed in a container, washed with distilled and acidic water, and then rinsed with alkaline water.

In this way, the penicillin will be divided into a certain part, concentrated and dissolved.

As for the large amount of penicillium and culture liquid mentioned here, it is a piece of cake for Wang Bin, after the steamed buns, buns, fruits, noodles and other foods become moldy, there are many penicillium on it, so it is really impossible to cultivate some directly.

The culture medium is even simpler, just find some rice and taro, grind the rice into juice and mix it with the juice made from taro as the culture medium.

For the simple preparation of penicillin, Wang Bin has always been handed over to Fu Bo to do, and he also opened up a small workshop at the back of his mansion, and selected his own soldiers to guard it day and night.

After Wang Bin did this in his mansion, he quickly made some low-concentration penicillins, and handed them over to Wu Liande and others to do clinical experiments to verify whether they were useful.

As for whether it is useful, Wang Bin is naturally sure in his heart, but sometimes it is better to see the result in person.

When Wang Bin hurriedly arrived in Fengtian, he met Wu Liande, and after meeting Wu Liande, Wang Bin immediately asked how the clinical trial of penicillin was.

"My lord, this penicillin you gave is a miracle medicine, and after his subordinates injected these wound-infected soldiers, the signs of these soldiers' infections were immediately controlled.

My lord, this medicine can literally cure all inflammation, and if it is popularized, it will definitely save countless lives! ”

The more Wu Liande spoke, the more excited he became, and he wished that he would be able to produce countless penicillins to save other lives.

"You are also clear about what the official said, but the preparation of penicillin is really difficult, and the yield is relatively low, and the penicillin that the official gave you is already dozens of days' production."

Different from what Wu Liande thought, in Wang Bin's opinion, the emergence of penicillin is enough to bring enough benefits to himself in the future, and if there are not enough benefits, Wang Bin will definitely not pass on the penicillin refining method.

Now all I have to do is to cover up the existence of penicillin and circulate it only on a small scale in the army, and use it to treat wound infections in soldiers.

When production increased, I would consider building a penicillin production plant to monopolize the production of antibiotics in this era.

After saying this, Wang Bin continued to say to Wu Liande.

"The current production of penicillin is limited, and it can only be supplied to the army first, and in the barracks that have just fought with the Japanese, I am afraid that there are many soldiers with infected wounds, so I will drag these soldiers back from the line of life and death for the time being."

"The meaning of the adult, the subordinates naturally understand, but it's a pity that there is such a miracle medicine, but the production is so small, if the production can be expanded, I am afraid that it can cure a lot of incurable diseases in this world."

Wu Liande's meaning is very simple, that is, he hopes that it can be mass-produced in the future and use this magic medicine to benefit the people.

In Wang Bin's opinion, if he could really produce penicillin on a large scale in the future, he would not mind benefiting his people while exchanging benefits from the foreign powers.

Therefore, Wu Liande's request was naturally agreed, and in the end, Wang Bin also promised to take out part of the penicillin for Wu Liande's research, and told Wu Liande that it was best to conduct a "skin test" before using penicillin to see if it would have other reactions to the human body.

The reason why Wu Liande suggested this was that Wang Bin was naturally worried that when penicillin was used, some soldiers would have allergic reactions. (To be continued.) )