Chapter 151: Expert's Help, Sulfonamides

Yang Tianfeng was a little puzzled, and said suspiciously: "During the Anti-Japanese War, military and civilian materials were very scarce, and the country's industrial attitude towards the rear would not be like this, right?" ”

Qiu Yuchi smiled bitterly and said something, which made Yang Tianfeng frown. Pen ~ fun ~ pavilion www.biquge.info

Before the war, China's steel industry not only stagnated, but also regressed compared to the Manchu and Beiyang periods. The war broke out, and due to the shortage of steel, the production of mountain artillery and howitzers was simply abandoned. The war made steel popular, and the government not only did not actively introduce policies to support the steel industry, but immediately raised taxes, from 1.28 yuan to 90 yuan in a year.

On the other hand, the share of government bank loans to industry is even more unimaginable, from only 3 percent in 40 to less than 1 percent in 43 years. By the fourth or fourth year, most of the large rear iron and steel enterprises had closed down or stopped production.

The big problem of the national government, or Chairman Chiang, is that it does not believe in the wisdom and strength of its own people and lacks the spirit of self-reliance. At first, I was buying, buying, and then I was asking Uncle Sam for it. There is very little attention to filling the gaps and research breakthroughs made by domestic scientific and technological workers, and there is a lack of support and encouragement.

For example, chemist Hou Debang was angry and researched a new method of making alkali on his own, inventing the "Hou's alkali making method", as well as a new process of co-producing soda ash and ammonium chloride fertilizer, but it was not taken seriously and failed to achieve industrial production; Mr. Zhang Dayu's Lidian Chemical Plant, which was built by Mr. Zhang Dayu to refine gasoline from lignite at low temperature, went through great hardships to refine oil, but the government did not support it, and there were many difficulties in manpower, material resources, equipment and funds, and finally it was forced to shut down.

In the later stages of the War of Resistance Against Japanese Aggression, China relied on the United States and Britain for 100 percent of gasoline, 95 percent of steel, 90 percent of medicines, and 80 percent of weapons and ammunition. In this way, all reliance on foreign aid has dealt a blow to the national industry, which has greatly disappointed many scientific and technological workers with the heart of "serving the country through industry," and even lost their jobs and livelihoods.

Now, the prosperity of short-term industrial development is just forced, and I have not given up "admiring foreign countries" from the heart. In the fight against the Japanese invaders, the government was always expecting the intervention of the great powers, and the heavy losses in the Battle of Songhu were largely due to this reason.

Yang Tianfeng pondered for a long time, shook his head with a wry smile, let's do our own thing!

"If you encounter difficulties, Yang is willing to help." Yang Tianfeng got up and raised his glass, and said enthusiastically: "Even if Yang Mou is not able to catch it in major matters, you can hire experts so that you can have no worries about food and clothing, and you can still do it with confidence." I'm afraid that you will look down on this small place and dislike it! ”

"General Yang is polite."

"Thank you General Yang, if you have no livelihood in the future, you will definitely come to ask General Yang for a job."

"General Yang is really to the point, and he does not lose his true character as a soldier."

………………

At this time, everyone only thought that Yang Tianfeng was joking, but they didn't know that Yang Tianfeng really hoped that more experts could stay, and the military production in the base area had developed rapidly, but he had higher requirements and goals.

"Mr. Qiu." It was originally a farewell reception, but Yang Tianfeng was really reluctant to let some experts go, so he found an opportunity to whisper to Qiu Yuchi: "Can you please leave a little later and guide us in the production and manufacturing of copper-clad steel plates." ”

Copper-clad steel plate? This is definitely a very innovative word, and it is also a rare new technology in the world. Qiu Yuchi looked at Yang Tianfeng and thought for a while, and asked tentatively, "Gun shells?" Is this possible? ”

"Totally doable." Yang Tianfeng nodded firmly and said, "We have already refined steel with ductility and tensile properties close to copper, but it can't completely replace copper, soβ€”"

Qiu Yuchi's eyes lit up, as a metallurgical expert, he knew what kind of huge impact this technology would bring, how important it was in the war effort, and it was the first of its kind in the world.

"This requires not only smelting technology, but also mechanical experts." Qiu Yuchi's gaze was focused on an expert who was laughing with people not far away, and he pouted, "General Yang, if that one can stay, the chances of success will be greatly increased!" ”

Yang Tianfeng understood it, but he had already noticed the mechanical expert, rolling mills, stamping machines, which were also the mechanical equipment he dreamed of.

There must be a way to impress him. Whether it is to continue to throw out professional information or hire with a high salary, Yang Tianfeng decided to spare no effort.

……………

During the war years, although there was occasional leisure or distraction, military and combat were always the main themes.

Yang Tianfeng returned from Luyi, discussing with experts on the one hand, trying his best to keep it, and on the other hand, he also paid attention to the battlefield and the results of the Anqing attack.

Sucheng and Kaifeng, if you add Anqing, the victory of the three battles will greatly shock the Japanese army defending the city. It is likely that the Japanese army will have to increase the strength of the garrison cities, which will have an obvious diversion effect.

With fewer mobile troops, the intensity and frequency of the sweeps will be weakened, and this will undoubtedly bring a more relaxed opportunity for the anti-Japanese armed forces, including the Third Column, to develop and grow.

Thoughts flew, Yang Tianfeng looked at Zhao Yurou and Hao Jiaqi, who were wearing white coats, busy doing experiments. Focused, Zhao Yurou showed a different demeanor from usual, with long hair pulled up, a slightly pursed mouth, long eyelashes, and slowly blinking eyes, which was really attractive.

"Hey, what are you looking at?" Zhao Yurou suddenly found that Yang Tianfeng didn't seem to pay attention to the experiment, but kept his eyes on her, smiling faintly, as if admiring and admiring.

"Oh, I'm watching you experiment!" Yang Tianfeng said stiffly.

Zhao Yurou rolled her eyes and said angrily: "Okay, then you say, what are the mistakes and omissions in our experiment, what's wrong?" ”

Yang Tianfeng laughed, got up and pretended to look at the test tubes, flasks and other experimental instruments for a while, coughed dryly, and said slowly under Zhao Yurou's white eyes: "A hundred waves are resting, clinical research was carried out in 1934, and in 1936 the streptococcal pharyngitis and its complications were cured of the youngest son of US President Roosevelt, and it was only then that it became well-known to the general public. ”

"We know that, too." Hao Jiaqi pushed his glasses with his finger and said: "It is said that research believes that the dye chromogenic group azo group is an effective group that makes it produce antibacterial effect. ”

Zhao Yurou nodded and said, "Our idea is to synthesize a large number of azo dye quilts, and then find a way to test their antibacterial activity. ”

"This supposedly study is erroneous and deliberately misleading by the Germans." Yang Tianfeng unceremoniously framed him, looked at the puzzled eyes of the two, took out two densely written pieces of paper from his pocket, shook them and said: "This is the information I just got and sorted out, and under the condition that the coal chemical industry has a certain foundation, it should be possible to carry out experimental preparation." If I could get another expert in biological bacteriaβ€”"

"Bring it." Zhao Yurou stretched out her hand to grab it, not beware of Yang Tianfeng, who was much more agile than her, and gave in by mistake and flashed her.

"Don't worry, be careful to flash your waist." Yang Tianfeng took advantage of the situation to hold Zhao Yurou's waist and stuffed the paper into her hand with a smile.

Zhao Yurou snorted, anxious to read the information, so she didn't pursue the matter of being taken advantage of.

P-aminobenzene sulfonamide was first synthesized in 1908 by the German chemist Paul Gelmo during the completion of his dissertation at the University of Vienna, when it was only studied as an intermediate in the synthesis of dyes, and its medicinal value was not yet recognized.

In 1932 chemists Josef Klarer and Fritz Mietzsch synthesized a derivative of p-aminobenzene sulfonamide, and in the fall of 1932, pathologist and bacteriologist Gerhard ? When Domac studied the antimicrobial effect of azo dyes in mice as animal models, he found that the red azo dye was a strong effect on the treatment of hemolytic streptococcal infections from thousands of candidate azo dyes. Domark was awarded the Nobel Prize in Medicine in 1939.

That is, it took a big circle, from p-aminobenzene sulfonamide to the dye "Bailang Duoxi", that people discovered this antibacterial drug.

"These drugs are effective not because they are dyes, but because they contain sulfonamides, which in turn are not dyes at all." Yang Tianfeng sat very close to Zhao Yurou, almost touched her hair, and explained: "You can make aniline from coal tar, and the main raw materials are available, and the two preparation methods, I think it is more convenient and faster to use the second one......

Zhao Yurou and Hao Jiaqi's heads were almost squeezed together, and they talked in a low voice, completely leaving Yang Tianfeng aside.

"My dad is almost here, he must be more professional." Hao Jiaqi said: "In my opinion, it's better to use this mixed two-book urea method, right?" ”

"I think so too." Zhao Yurou nodded in agreement, "Then let's start!" ”

After the two girls finished talking to themselves, they realized that Yang Tianfeng, who was being ignored, was rolling his eyes and was unhappy.

"We're going to get to work." With a direction for work, Zhao Yurou's mood also improved, with a smile on her face, she pushed Yang Tianfeng, "Let's go, you're so busy, you have a lot of official business to deal with, right?" ”

"I've made so many phone calls asking me to come and guide, and now I'm telling me to go quickly." Yang Tianfeng stood up reluctantly, muttering in his mouth.

"You went to instruct the coal chemical plant, and there were difficulties there." Zhao Yurou pushed Yang Tianfeng's back, but he was walking slowly.

"Okay, okay." Yang Tianfeng shook his head helplessly, and did not forget to advise: "Sulfonamides are toxic, you two do a good job of protection, that mask, and firefighting equipment, you must have all ready." If you notice a dry cough, loss of appetite, bad taste in the mouth, headache, dizziness, fatigue, listlessness, and sleepiness after work......"

"Know, isn't it all written on that paper! Excuse me, call Xiao Zhang and Xiao Wang, okay? Zhao Yurou stood at the door and smiled at Yang Tianfeng, stretched out her hand and closed the door.

Well, how bad is it. Yang Tianfeng pursed his lips, but he was happy for Zhao Yurou in his heart. Down-to-earth, do something practical, and maybe make achievements in his professional field, which is exactly what he hopes. (To be continued.) )