[Anti-Japanese Iron Blood King] Chapter 321: The Establishment of the Rear General Courtyard (Ask for Subscription!) ）

No one knows what the mold that Ma Zheng and Li Lanqing talked about now is, but in later generations he has a rather loud name - penicillin.

As for penicillin, there must be no one in later generations who did not know its great name, and the invention of this powerful antibiotic quickly caused a sensation around the world, and was even listed as one of the greatest inventions of the 20th century.

In fact, early research on penicillin has been going on for a long time, and people have discovered that there is such a thing that can kill germs. Until then, mankind had not mastered a drug that was highly effective in treating bacterial infections with few side effects, and if someone contracted tuberculosis, it meant that the person would soon die, and in ancient China, the disease had a terrible name - tuberculosis.

In order to change this situation, researchers have been exploring for a long time, but the breakthrough in this area is due to an accidental discovery. Alexander Fleming discovered penicillin by a lucky mistake, and in the summer of 1928, when Fleming was on vacation, he forgot about the bacteria growing in the petri dish in his laboratory. When he returned to the lab three weeks later, he noticed a clump of green-green mold growing in a dish of Staphylococcus aureus that had been accidentally exposed to air.

When Fleming looked at the dish with a microscope, he was surprised to find that the staphylococcal colonies around the mold had dissolved, which meant that some kind of secretion from the mold inhibited staph bacteria. Subsequent identification showed that the mold was Penicillium punctata, so Fleming called the bacteriostatic substance it secreted penicillin.

Unfortunately, Fleming was never able to find a way to extract high-purity penicillin, so he cultivated penicillium strains from generation to generation, and in 1939 gave the strains to the British pathologist Flory and biochemist Chin who were preparing to systematically study penicillin.

After a period of intense experiments, Florey and Chann finally extracted the penicillin crystals by freeze-drying. Afterwards. Flory found a mold on a melon that could be used to extract penicillin in large quantities and prepared a corresponding culture from corn flour. Since then, a series of clinical experiments have confirmed the efficacy of penicillin against streptococcus, diphtheria bacillus and other bacterial infections.

The reason why penicillin can not only kill germs but also do not damage human cells is that penicillin contains penicillin can hinder the synthesis of the cell wall of pathogens, resulting in the lysis and death of germs, while human and animal cells have no cell wall. But penicillin can cause allergic reactions in some people. Therefore, it is necessary to do a skin test before application.

Driven by these research results, American pharmaceutical companies began mass production of penicillin in 1942. By 1943, pharmaceutical companies had discovered ways to mass-produce penicillin. At the time, Britain and the United States were at war with Nazi Germany, and the new drug was very effective in controlling wound infections. By 1944, the supply of medicine was sufficient to treat all Allied soldiers who fought during the Second World War.

Penicillin is definitely not much worse than any advanced weaponry in the war, or even surpasses it. A true commander should know that the most valuable thing on the battlefield is not the iron lumps, but the soldiers. Every experienced veteran is a valuable asset, and in fact these riches diminish with the attrition of war. A small number of them died directly on the battlefield, while many more died of their wounds. As long as the wound does not suppurate and does not become infected on the battlefield, the chance of complete recovery of the wounded is more than 80%.

By this time, the haze of world war had already hung over most of the world, the German madman had become the Führer, and the German tanks had already entered the Rhine Demilitarized Zone, and just next year, the mustache would command his Army and Air Force to raid Poland. Challenge the whole world. Soon the whole world will be dragged into the quagmire of war, and the number of dead soldiers will be astronomical.

Therefore, the study of penicillin must be put on the agenda. In Ma Zheng's view, this drug is not only a good medicine to reduce his own casualties, but also a stepping stone to open the coffers of various countries.

As for whether penicillin can really be used in clinical trials, Ma Zheng has no doubts about this. Ma Zheng knew very well how penicillin was cultivated and purified, although he had not tested it himself, but as long as he told the real experimenters the methods he knew, he would surely have results soon.

There are many things that you can't do. It's that I don't know what to do. Like Fleming, he had already discovered penicillin in 1928, confirming the existence of such a powerful anti-inflammatory substance. However, because I don't know how to purify, ten years later, penicillin is still only in the laboratory and cannot be used on a large scale.

But Ma Zheng also knows. Fleming will soon be working with Florey and Channe, and in the next few years, penicillin drugs will be popular all over the world, and penicillin, a peerless drug comparable to gold, will soon come out, leaving him not much time.

Fortunately, a large amount of experimental equipment and Japanese materials were seized during the attack on Datong, and many Japanese military doctors were also captured.

Originally, Ma Zheng's first reaction to these demons who used living people as experimental raw materials was to pull them all out and shoot them. But tens of thousands of miners needed medical treatment at the time, as well as the wounded, so they all had to be left behind. Fortunately, these guys are not real soldiers, and they have not been brainwashed by the spirit of bushido, and they know what it means to be afraid, so they are more cooperative with Ma Zheng's orders, so Ma Zheng left their lives, and now it is just right for them to cooperate with Li Lanqing to study penicillin drugs.

However, the relevant confidentiality work still needs to be done, and penicillin is very important and must not be leaked. In particular, we must not let the Japanese know about it, otherwise the consequences will be unimaginable.

With Ma Zheng's full support, the field hospital of the Suicha Military Region was soon split into two, and some doctors and nurses moved to Jining to establish the field hospital of the Suicha Military Region, and the director was still Li Haiyan. Tang Maogong, former deputy director of the Logistics Department, was appointed president of the rear hospital because of his outstanding management ability, while Li Lanqing served as vice president of the hospital.

At the time of the establishment of the rear general hospital, a department under the personal command of Li Lanqing was secretly established, and this department existed independently in the relevant systems of the entire rear general hospital, and was only responsible to Ma Zheng alone, and even political commissar Yun Jian and others had no right to intervene.

In order to ensure that the research would not be disturbed, Ma Zheng deliberately asked Teniu to transfer a combat detachment from the special operations brigade and a company from the guard brigade to form a garrison team to protect the safety of the field hospital around the clock, to be precise, to protect the safety of Li Lanqing and others.

Although Li Lanqing was a little unconvinced of his ability, he was quite unsure when he saw Ma Zheng put on such a big battle. But thinking that Ma Zheng acted recklessly, but did not do anything that did not take care of me, he must have a reason for doing so, so he quickly settled down and began to study the kind of mold mentioned in Fleming's paper.

Under the personal guidance of Ma Zheng, they soon discovered this miraculous mold, although this is only the beginning, and the mold found can only prove the existence of penicillin, which has nothing to do with clinical trials, but it has established Li Lanqing's confidence.

As the saying goes, if you are not afraid of being unmotivated, you are afraid of being hopeless. Seeing that the mold mentioned in Fleming's paper really exists and really has the function of killing viruses, Li Lanqing's research work has the motivation and confidence, and with absolute confidence, supplemented by the successful method that has been demonstrated in practice, will it be far from the advent of penicillin that can really be used in clinical trials? (To be continued.) )