Section 178 Wu Liande
Yang Chao's crossing obviously did not affect the plague, and at the end of October, just after the northeast entered the autumn, a plague suddenly began to break out from Harbin. Pen, fun, pavilion www. biquge。 info
At that time, Yang Chao was still dealing with military operations on the front line, so he didn't have time to deal with it, and he didn't have experts to deal with such things as the plague, although the army that Wu Peifu formed step by step was still very regular, and the number of military doctors was not small, but military doctors were generally surgical specialties, for example, Yan Fuqing, the current director of the military hospital, was only a student who graduated from the medical school of St. John's University in Shanghai, and his medical knowledge was not rich.
So in the end, it was dealt with by Yuan Shikai, after all, the resources mastered by Yuan Shikai were far greater than those of Yang Chao, especially in terms of talents.
Although he has attracted a large number of engineering students studying abroad, in medicine, Yang Chao has not been able to attract too much, so there are really not many medical talents.
Yuan Shikai really has a talent in his hands, a doctor of medicine named Wu Liande, an overseas Chinese born in the British colony of Penang, whose ancestral home is Xinning, Guangdong, graduated from Penang Public School, and received the Queen's Scholarship to study medicine at Cambridge University in the United Kingdom, studied for eight years, and got a doctorate.
The most important thing is that Wu Liande's major is called tropical diseases, which is actually to study various tropical infectious diseases and deal with bacteria. His graduation thesis was all about tetanus bacteria. Therefore, it is indeed most appropriate for him to deal with the plague problem.
Wu Liande was the chief medical officer of the Beiyang Army built by Yuan Shikai, and he also brought several other military doctors, and Yang Chao also sent him a hundred military doctors to cooperate, and asked the Harbin garrison to obey Wu Liande's orders.
Wu Liande took a variety of prevention and control measures, such as strengthening railway quarantine, controlling traffic, isolating epidemic areas, cremating the corpses of plague patients, and establishing hospitals to accommodate patients, and soon brought the epidemic under control.
When Yang Chao returned to Harbin, although the plague had not yet passed, the large-scale infection had been controlled.
Yang Chao also saw the research room established by Wu Liande in the infectious disease hospital in Harbin, where plague bacteria were cultivated in a large number of glassware, and these samples were constantly made into samples.
Moreover, Wu Liande's research has also been quite fruitful, for example, he found that the source of infection of plague, including marmots, is also one of the sources of infection. It has changed the medical community's belief that rats are the only causative source.
Visiting Wu Liande's laboratory, Yang Chao was thinking about other questions.
"The plague is caused by bacteria, and the best antibacterial should be penicillin, I don't know if penicillin has an inhibitory effect on this bacterium!"
As a liberal arts dog. Yang Chao's greatest knowledge of germs is penicillin, as for other streptomycins, erythromycin, etc., he knows the names, but he can't tell the difference between these mycins at all.
Impressed with penicillin. That's because the story of penicillin is more legendary, the British microbiologist Fleming cultivated some staphylococci, but forgot, went home a few days later, and found that a green mold grew in a culture vessel with poor air tightness, near this green mold, staphylococci was inhibited, this green mold is Penicillium, and the secreted penicillin has a bactericidal effect.
Thinking of this story, Yang Chao couldn't help but glance at Wu Liande's cultivation vessel twice. He is currently cultivating plague germs with meat, and I wonder if he will continue his research if he stumbles upon the bacteria suppressed by some kind of mold.
After being sent out of the hospital by Wu Liande, Yang Chao began to think about how to guide Wu Liande to discover penicillin.
It's really not easy for him as a liberal arts student, because the devil knows what penicillin looks like, but fortunately he has a cross-era spaceship.
At night, a robot was secretly sent to steal some samples of plague germs from Wu Liande's laboratory.
Then there was the experiment, Fleming's Penicillium came from the air, and Yang Chao asked the spacecraft to constantly filter and capture some fungi from the outside air, and then randomly put these molds into Wu Liande's samples for observation.
He also found a few molds that could inhibit the plague germ, and after a few days, enough samples were produced. Then let the robot secretly send these molds into the utensils of Wu Liande's laboratory.
When Yang Chao went to the hospital a few days later, Wu Liande excitedly told Yang Chao that he had found several molds that could inhibit plague bacteria, and was very excited to tell Yang Chao the significance of this discovery. He believed that the plague could be completely eradicated, which was of great significance to mankind, and he gave examples such as the Black Death to introduce Yang Chao to the horror of the plague.
Seeing that Wu Liande was guided to the path of discovering penicillin, Yang Chao didn't care about him.
In fact, what Yang Chao didn't know was that the sample he sent to Wu Liande was actually not Penicillium at all. It's streptomycetes, Penicillium can't suppress plague bacteria, but Streptomyces can.
However, this discovery of drugs from fungi has invisibly opened up a way for human medicine, which is even more important than the discovery of one or two antibiotics.
After that, Wu Liande continued to publish his research results, but there was not much repercussions in the world, and the scientists were quite interested at first, but after seeing the slowness of the research, no one cared.
In fact, after Fleming discovered penicillin, he also encountered the same embarrassment, and the penicillin paper was published in 1929, but it was not until ten years later that the German scientist Qian En found this old paper from the waste paper heap and became interested in research.
But Wu Liande focused on his own research, which lasted for several years, before his research was taken seriously, and at that time, Wu Liande had already established a streptomycin production plant with Yang Chao's investment, and had achieved a monopoly advantage in the field of pathology, which Westerners could not catch up.
However, Wu Liande's scientific research was not so smooth, this was still the trouble that Yang Chao created for him, Yang Chao himself didn't know what the kind of fungus that looked like a monster after being enlarged was, but he found that there were several fungi that had an inhibitory effect on plague bacteria, so they were all stuffed into Wu Liande's culture vessels.
Wu Liande found that there were several kinds of fungi that inhibited the plague bacteria, he slowly isolated them, and then conducted a separate study, and found that the secretions of several fungi did have an inhibitory effect on the plague bacteria, but the toxicity was very large, and it could directly poison animals and even people.
That's why Wu Liande's discovery was ignored by scientists, because no matter how you look at it, it has no effect, and what is the use of life-saving drugs that kill people together? Even Wu Liande almost gave up this kind of research until the less virulent Streptomyces was discovered, and he was confident to continue research, but by then his research had completely failed to arouse the interest of Westerners. (To be continued.) )