[Anti-Japanese Iron Blood King] Chapter 439: The Epidemic Extinguished (Ask for a subscription, ask for a monthly pass, ask for everything!) ）

It is no wonder that Ma Zheng is frightened, he knows the whole detailed process of penicillin drugs from discovery to clinical practice. The real penicillin was refined by Qian in the winter of 1940, and the quantity was very small. Although this is a major breakthrough, it is still far from clinical application.

It was not until around 1941 that Howard Flory, a pathologist at the University of Oxford, England, and Money, a biochemist, realized the isolation and purification of penicillin. Later, Flory found a mold on a melon that could be used to extract penicillin in large quantities and prepared a corresponding culture from corn flour.

Driven by these research results, American pharmaceutical companies began mass production of penicillin in 1942. It wasn't until 1943 that pharmaceutical companies had mastered the method of mass production of penicillin.

And now it was only 1939, which meant that the real penicillin drug was only produced three years later, how could Wu Liande have this drug? Could it be that there is a problem with his memory, or is this Wu Liande also a time-traveler?

More importantly, Ma Zheng has always regarded penicillin as an important means to solve the problem of raising funds for the Eighth Route Army, and even did not hesitate to send his wife to the United States to do business. But if penicillin drugs had already appeared in this world, then his plan would have become meaningless, so Ma Zheng would feel frightened without the slightest sense of joy.

However, since the people had already sent the things, he could not live up to their kindness, and immediately ordered someone to send the penicillin sent by Wu Liande to the field hospital for the patient to take and watch its clinical manifestations.

In fact, even if Wu Liande didn't send someone to send this drug, he would soon be using penicillin for infected patients. After all, all other methods have been used, but they still can't restrain the spread of germs, so Ma Zheng can only try his luck with penicillin at this time.

Although the production of penicillin in the Suicha Military Region is not very high, and the types of drugs are very small, and they are mainly suitable for symptoms such as postoperative infections, there is no drug research specifically for the plague. After all, Ma Zheng was not an immortal, and he could not have imagined that the Japanese would be so mad as to make a fuss about the prisoners of war and deliberately spread the plague in the defense area of the Suicha Military Region.

But now Ma Zheng has no choice, whether it is useful or not, you have to try it first, anyway, there is no drug that is really effective in treating plague, maybe penicillin is still useful.

Therefore, Ma Zheng had ordered someone to bring a batch of penicillin liquid from Guisui to see if the plague could be well controlled by intravenous injection. Well, now that Wu Liande has also sent someone to send penicillin medicine, let's treat it with the drug he sent first and see the actual effect.

However, what made Ma Zheng feel cold was that although several patients who were treated with penicillin did not die, their condition did not improve, and they were still groggy every day, and their body temperature was kept above 39 degrees every day, which means that penicillin had no effect on this terrible plague.

Ma Zheng's heart was completely panicked, penicillin was his biggest hole card, and now it had lost its effect. Watching hundreds of people die in pain every day, Ma Zheng's heart is like a knife, but there is nothing he can do.

However, things took a turn for the worse on May 18, when Li Lanqing came to Ma Zheng and told him about her discovery. Through the analysis and study of the drugs sent by Wu Liande, Li Lanqing found that the drugs that looked like penicillin did have penicillin in them, but the content was very low, and the penicillin content in one of his tablets did not even account for 10%, so it could only be said that it was a penicillin-like drug, not real penicillin.

Hearing this, Ma Zheng was immediately relieved, it seemed that it was not that there was a problem with his memory, let alone that Wu Liande was also a traverser, but that kind of medicine was not penicillin at all, but pseudopenicillin with a certain penicillin component.

Sure enough, after Ma Zheng verified with the Military Command Bureau of the National Government, he learned that it was indeed not penicillin as he imagined, but a combination of Chinese and Western medicine prepared by Dr. Wu Liande himself.

It is said that he heard that the paste with green hair can make the wound heal, so he did several tests, and found that although the effect is there, it is very general, so he added some traditional Chinese medicine such as banlan root to make this penicillin-like drug.

Although this medicine does have a certain effect on mild infections, its main ingredient is still the root of the banyan, so the effect on dealing with this kind of virulent infection is very general.

After reading the telegram sent by the military command department, Ma Zheng was overjoyed. Since the previous use of real penicillin did not mean that penicillin did not have an effect on the plague, there may be a glimmer of hope.

After learning the truth, Ma Zheng immediately ordered Li Lanqing, Wang Jitang and others to use penicillin drugs on infected people to determine the effect of this drug on plague.

On the afternoon of May 21, the first batch of 500 selected patients finally had an effect after three days of treatment. Over the course of 3 days, the 50 patients were treated with 9 sessions of penicillin. By the evening of the 10th, the temperature of the fifteen patients who had just become ill began to drop, their heads did not hurt much, and their faces finally looked bloody.

The effect is surprisingly good, indicating that penicillin does have a good effect on this plague. However, those who were selected before were all people with good physical fitness and the onset time was not very long.

Subsequently, Li Lanqing and others treated patients who had the onset of the disease for 7 to 20 days, and found that the effect was not as good as before. However, almost all patients who were injected with penicillin did not have an elevated temperature, and some people with better physical fitness even improved.

As it turned out, Ma Zheng's conjecture was correct, and real penicillin did work wonders in treating plague. When dozens of Japanese-made Type 94 military vehicles loaded with penicillin drugs arrived in Zhangjiakou, the plague incident had already entered the countdown.

The purified penicillin drug is completely equivalent to the miracle medicine for people who have basically not used antibiotics in this era, and in just one week, the epidemic in Zhangjiakou City has been controlled, and then Fengzhen, Xinghe, and Shangyi have also reported good news, and the plague that has ravaged the Suicha Military Region for nearly a month has finally been completely controlled.

However, although the plague was temporarily controlled, the crisis in the Suicha Military Region had not yet been resolved, mainly because the Japanese army had gathered four divisions on the front line of Zhangda, and once they knew that Ma Zheng's headquarters had controlled the plague, then the Japanese army would inevitably launch a full-scale attack on the Suicha Military Region.

As of May 27, the total number of direct deaths in Zhangjiakou and other places was 7,634, plus those who were secretly buried, the plague caused at least more than 10,000 deaths to Ma Zheng's department.

In addition, the plague also completely destroyed the Suicha Military Region's plans for industrial construction and agricultural production. Because of the plague, a large amount of land in Chahar province has been barren, and only two-thirds of the land in the province has been sown, and it is conceivable that if the harvest is good, it will barely make do this year. If the harvest is not good, there will definitely be a ****** in Chahar province.

In addition, the plague has had a number of adverse effects on the Suicha Military Region's ability to attract foreign population, and the entire region has been completely isolated since the outbreak of the plague. Not to mention that the phenomenon of rushing to Guisui in droves and defecting to the Eighth Route Army is gone, and there are still a large number of people fleeing, they don't want to stay here and wait for death. After all, the plague is a living god of death in this era, and once infected, the mortality rate reaches almost 90%.

Fortunately, thanks to the presence of penicillin, by May 31, the number of deaths in Zhangjiakou and other epidemic areas plummeted from 1,123 per day at the peak to 213, and then to 116, 38, and 6. By June 7, no deaths had been reported, the death toll had finally reached zero, and the epidemic had finally been extinguished. (To be continued.) )