Chapter 106 Penicillin
Chapter 106
In 1929, Fleming published a research paper on the bactericidal effect of mold culture in the British Journal of Pathology, but it was not noticed. Fleming pointed out that penicillin would have important uses, but he could not invent a technique to purify penicillin himself, so the drug remained unused for more than a decade.
This time and space changed slightly, and the medical research laboratory under the Chinese Academy of Sciences, with the support of Fang Jianxiong's private funds, purchased Fleming's invention patent and organized people to conduct subsequent research. Because this research is Fang Jianxiong's private injection of funds, according to the original agreement, the owner of the research results of the medical research laboratory is Fang Jianxiong. The research process did not go smoothly, although Fang Jianxiong had a little bit of Baidu's basic knowledge in his memory, and pointed out a general direction, making a fuss about corn and melons. However, the research continued slowly for more than three years, and finally found a way to produce purified penicillin on a large scale.
Gong Rui, the scientist who led the study, is a figure who does not exist in parallel history, and due to the popularization of the compulsory education system and the increase in the system of public international students, many scientific heroes who have not appeared in parallel history have been born in this time and space. In fact, there are not many fierce people to learn from the Republic of China in parallel history, after all, the base is too small. The so-called masters are mainly concentrated in the liberal arts. In the real history of the Republic of China, there was not even a real science and engineering university, there was a person in Qingdao to run a pure science and engineering school, and then this person was very miserable, which was not tolerated by the times. Hehe, a university without liberal arts, that's okay, this is the cruelty of history.
Gossip aside. The research team led by Gong Rui has always been a purely Chinese team. Gong Rui, led by Gong Rui, graduated from Wuhu Yijishan Medical University in 1919, and was recommended by the school with excellent grades to participate in the examination for studying in the United Kingdom and passed Guò. In 1924, Gong received a master's degree from St. Mary's Medical College and subsequently joined Fleming's Shiyàn group. It is precisely because of this that Gong Rui has a full understanding of this research and discovery, and under the premise that Fleming's invention is not taken seriously, Gong Rui is invited to return to China to preside over the follow-up research.
In fact, the way to purify and mass production was found at the beginning of the year, and the reason why it has not been disclosed for a long time is that clinical trials are underway. After all, Fang Jianxiong knew that penicillin would be allergic. Not everyone can use penicillin. The problem of skin testing was finally solved, and after more than 200 clinical successes, Gong Rui personally made a report to President Fang Jianxiong, who had poached him back from the UK.
The news of penicillin purification and large-scale production appeared at this time, and Fang Jianxiong was pleasantly surprised. With another stack of thick chips in his hand, it's hard not to be surprised. A large number of people were sent at once. After going to Europe and the United States to solve the patent problem, he announced the news to the world in a hurry.
The purification and large-scale production of penicillin, as well as the report of clinical trials, occupied the front page and the second page of the "Republic of China Times". All other news gave way, and the news of the big president was all lined up in three pages, of course, this was Fang Jianxiong's order. In this region of China, who dares not to put the news of national leaders on the front page, especially the government mouthpiece like the Republic of China Times.
A large number of facts are the most telling of the day, the news of penicillin was officially announced to the public. The whole world went crazy for the news. On November 15, the Medical Branch of the Chinese Academy of Sciences held an official press conference, and Gong Rui, the leader of the penicillin project, personally answered reporters' questions.
On this day. The U.S. president's envoy was eventually identified as Hopkins, and Hurley traveled to China as an aide. Let's put it this way, after Roosevelt became president of the United States, the dollar depreciated as it did historically. The Silver Group did make a lot of money, but the fattest pig in history was in this time and space. The early cancellation of the silver standard cannot but be said to be a matter of deep regret to the silver group.
Roosevelt was not Hoover, and he would never allow the government to sit idly by and watch the "freedom" of the American economy. Although the Chinese were ahead of the curve in this time and space, the Roosevelt administration was still moving according to the original historical trajectory. The difference is that on the blacklist of Roosevelt's containment in this time and space, China is the first to bear the brunt of the Asia-Pacific region. With the intervention of the U.S. government, the momentum of the U.S. economy is on the rise. After finishing his internal affairs, Roosevelt turned to China. Don't believe in any nonsense "friends", there are only interests between countries and countries. The strategy of turning the Pacific Ocean into an inland lake of the United States was actually born in the hands of Roosevelt. One of the greatest presidents in American history has betrayed China's interests in real history. If it weren't for the fact that the strategic center of gravity of the United States had always been Europe, Roosevelt's means of containing the Republic of China government in this time and space might have been even more severe.
It's just that what Roosevelt didn't expect was that Fang Jianxiong's counterattack came so strongly. Roosevelt was a very intelligent person, how could he not have imagined the connotation of the Republic of China government's sudden fuss on the issue of Sino-US relations? The reality is that the US economy has not yet recovered to the point of economic crisis, and the Chinese government's retaliation against certain small actions of the US government can be said to be extremely intense. This also led Roosevelt to re-examine his diplomatic posture toward China in the face of careful intelligence research and analysis. There is no doubt that the United States is strong. But the Republic of China in this time and space is not the weak Republic of China in history, it is not something that the US government can manipulate at will, and it is not the object that the Silver Group can be slaughtered as a fat pig. In particular, after the Chinese government announced its withdrawal from the Washington Naval Treaty by the Japanese government, the government of the Republic of China did even more so, not only withdrawing from the Washington Naval Treaty, but also directly withdrawing from the League of Nations. As soon as the U.S. government made a small move, the government of the Republic of China immediately took strong retaliatory measures. Speaking of which, these methods can be said to kill 1,000 enemies and lose 800 themselves, but the government of the Republic of China did just that. This shows the fierceness of Fang Jianxiong's character and the will of the government of the Republic of China to never give in.
Chinese, who have been inferior for nearly a hundred years, have begun to regain self-confidence in the past two decades. The news of the research and development of penicillin has undoubtedly brought the Chinese to a higher level in the process of regaining self-confidence. What the Westerners did not do, the Chinese did.
"Without a doubt, this is one of the greatest inventions in human history. The whole world should be grateful to the Chinese medical community for this great invention and to Mr. Gong Rui for his great medical contributions to the world. Medicine knows no borders, and the American medical community invited Professor Gong Rui to give lectures in the United States. The Wall Street Journal said that there seemed to be something in the words, and it was not a good word.
"The birth of penicillin completely solved the problem of postoperative infection, which is a victory for Asians, and this victory once again proves the excellence of the yellow race." The news from Japan's Yomiuri Shimbun seems a little strange at this time.
Gong, who presided over the purification of penicillin, studied at St. Mary's Medical College and served in Mr. Fleming's laboratory. Gong's success is undoubtedly a continuation of Mr. Fleming's great discovery. We would like to pay tribute to Mr. Gong and his team, this is a medical invention that can glorify the history of mankind. Reuters reported that it was clear that the tone of the British was sour, and once again emphasized the importance of Fleming's scientific discovery, and laid the groundwork for some follow-up requests.
"As a traditional friendly country of China, the German government congratulates the Chinese people on having such a great scientist as Mr. Gong Rui, whose scientific research results will surely shine as a latecomer to human medicine." In the history of the future, countless people will benefit from this great medical achievement, congratulations to Professor Gong Rui, and on behalf of the German people, I would like to pay high tribute to him! "The tone of the media in Germany is relatively uniform, which is a major change after Hitler came to power.
After the press conference, the overwhelming coverage pushed Gong Rui and penicillin to a peak. But soon there was a subtle change in the angle of media coverage, especially in foreign media. Why? The price of penicillin is not cheap, and a box of penicillin produced by the Northern Pharmaceutical Factory for six injections costs 600 yuan. That is, a needle is 100 yuan, which is equivalent to 25 dollars. Even so, the first batch of 500,000 boxes of penicillin injections was sold out in just one week. Because there is no bacterial resistance, the effect of penicillin is even better and outrageous. The expensive penicillin injection has become a must-have life-saving drug for some well-off families in China. Regardless of whether you are sick or not, you have to keep a box at home for later, you must know that the mortality rate of wound infection in this era is very scary.
Not to mention the fact that foreigners buy penicillin, even the domestic market cannot be satisfied. Foreign foreign banks keenly seized this opportunity to make money and bought penicillin at a high price, and in just half a month, the black market price of penicillin was speculated to 1,000 yuan per box, and even this could not meet the demand of the market.
The northern pharmaceutical factory that produces penicillin counted the money and counted the cramps, and the patent owner of penicillin legally belongs to the northern pharmaceutical factory founded by Fang Jianxiong's wife, Lu Bicheng. In other words, in fact, this research belongs to the lady collective in the backyard of the Fang family. Of course, it is the talented woman Lu Bicheng who is in charge of the property in the backyard of the Fang family.
Founded in 1920, the legal owner of the North Pharmaceutical Factory is Lu Bicheng, and from the early days of the establishment of the enterprise, the North Pharmaceutical Factory was the financial supporter of several research laboratories under the Medical Branch of the Chinese Academy of Sciences. According to the agreement, for every scientific research achievement, the Northern Pharmaceutical Factory will share the profits with these laboratories. In the case of penicillin, for example, the original agreement was signed for 30% of the profits to go to the laboratory.