Two-two-two, the agency is too smart

The boiled duck flew!

Sun Yuanqi wanted to jump and scold with Arthur, but he was only hindered by Zhao Jinghui's presence and wanted to maintain the dignity of his teacher, so he took a deep breath and asked: "Jinghui, I remember that Mr. Man Ledao did not participate in the research of artemisinin, how did he get the experimental data?" ”

Zhao Jinghui's face was a little pale: "We wrote a paper a few years ago and sent it to you for review. No pop-up window update fast // You said that the paper would be published after a while, so I took it back and put it in the lab. Mr. Man Lok Dao got the news out of nowhere, so he came to me and said that he wanted to see how the paper was written.

"He was my teacher and taught me for a long time, and I didn't say no. And this is the first time I've written a paper, and I always feel unconfident. In my heart, I think it's good to ask a few more teachers to read before publishing and to make fewer mistakes. He borrowed the paper for three or four days, returned it to me, and then went back to China on vacation. Didn't expect ......"

Seeing that Zhao Jinghui was crying, Sun Yuanqi had to comfort her: "I don't blame you for this, who would have thought that the sanctimonious Manle Dao would be so despicable?" It is difficult to draw the skin of a tiger and draw bones, and you don't know your heart! ”

Zhao Jinghui said: "Sir, artemisinin has been preemptively registered by Mr. Manle Dao, can we still produce and sell it?" ”

"Absolutely!" Sun Yuanqi replied categorically, "Manle Dao has only registered patents in Canada, the United States, and Mexico, while we have registered patents in Europe, at least we can sell them in Europe now." As for the Americas, it was up to Arthur to theorize in court! ”

Arthur was like a fighting rooster: "That's right! We have to reason with that scoundrel and let him know that the United States is also a place where the law is spoken, and there is no good fruit to eat in plagiarism! ”

Zhao Jinghui asked timidly: "Will Mr. Man Ledao still go back to China?" ”

"Hmph," Sun Yuanqi sneered a few times, "Don't look at him as a foreigner, when I get to China, I have one hundred and eighty ways to round and pinch him." If he dares to come back, I will let him know that Lord Ma is three-eyed! ”

When Zhao Jinghui heard this, his expression was relieved: "If Mr. Man Ledao doesn't return to China, I'm afraid that he has applied for a patent for artemisinin, and there is no way to produce it." ”

"Oh?" Sun Yuanqi and Arthur were surprised at the same time.

Zhao Jinghui explained: "Artemisinin is extracted directly from Artemisia annua. In our previous studies, we found that no other natural plant other than Artemisia annua contained artemisinin. Although Artemisia annua is a widely distributed species in the world, the content of Artemisinin varies greatly with different origins.

"We have mobilized all students and international students to collect samples of Artemisia annua from all over the world, and the data show that except for parts of eastern Sichuan, Fujian, Guangxi and Hainan in China, the content of artemisinin in the normal production of Artemisia annua in most parts of the world is very low and has no use value. If you really want to formally build a factory to produce drugs, only the yellow artemisia grown in the Wumu Mountains in Youyang District, Chongqing has industrial refining value, and no other place can do it. ”

This peak turned around, making Sun Yuanqi and Arthur laugh heartily.

Arthur said: "I was initially worried that the bastard would use the profits from selling ** to hire a team of lawyers to fight a protracted war with us. Now that he can't produce with a patent, why should I be afraid? In addition to asking the patent office to reject his application, I would also appeal to the court to sue him for plagiarism and demand huge damages. Hmph, I'll slowly consume him, let him go bankrupt and ruined! ”

"God help me! Youyang is just a county under the Chongqing Prefecture, and there is no need to borrow the prestige of my uncle and grandfather, just with me, the left servant, it is enough to make Youyang County bow down, without my order, not a single yellow artemisia can not flow out of the county! Sun Yuanqi let out a sullen breath in his chest, "But, Jinghui, it seems that the words you said just now didn't appear in the paper, right?" ”

"Well," Zhao Jinghui said like a gnat, "the title of the paper is "The inhibitory effect of Artemisia annua extract on malaria parasites", which mainly talks about how to extract artemisinin and the inhibitory effect of artemisinin on malaria parasites. As for the distribution of Artemisia annua, it is a biological aspect that is not covered in the paper. ”

"Well, that's great! Originally, it was your unintentional move, but it turned out to be full of joy and said fiercely, I'm afraid that he will vomit three liters of blood when he hears it, right? Sure enough, the reason is clear, and the retribution is not happy! Sun Yuanqi was a little proud.

When Arthur returned from the United States, he was already sleepy and dying, and he had only survived until now with a wave of anger in his chest. Now that this matter is clear, I can't hide my sleepiness anymore: "Johnson, Miss Zhao, you talk slowly, I lost my company first." With that, he staggered back to rest.

Seeing Arthur's resignation, Sun Yuanqi made Zhao Jinghui a cup of tea and asked, "Jinghui, what have you been busy with in your laboratory lately?" ”

Zhao Jinghui took the teacup: "A few days ago, I have been studying how to industrially extract artemisinin, and now it is almost completed." According to calculations, about 1 kilogram can be extracted per day, which is enough to ensure the production of powder injection in the factory. ”

"So what's next for you? Any good ideas? ”

Zhao Jinghui was a little embarrassed: "The first ** developed by the laboratory is a special drug for the treatment of malaria, and everyone is very excited. After the project ended, some people started to get a little confused. During the small talk, they even joked that they would study a cure for dysentery, cholera, tuberculosis and even cancer. ”

Although it may be unrealistic, sometimes dreams are the biggest motivation for human beings to devote themselves to scientific research. Sun Yuanqi didn't mean to laugh at it: "It's excellent that they have these ideas, as long as they dare to think and dare to do, there will always be a day when they will achieve their goals." Jinghui, what do you think of yourself? ”

Zhao Jinghui said: "There are some ideas, but they are all messy, such as drugs to treat various infections and inflammations, but I don't know how to implement them. So I wanted to ask Mr. for an idea. ”

How to achieve it, this is the gulf between dreams and reality. Many people in the world want to make a fortune, but how many can really make a fortune? Many people in the world want to spread their wings and soar into the blue sky, but how many can really fly in the sky? Many people in the world want to live a long life, but how many have really lived past 100 years old? The ideal is very plump, and the reality is very skinny.

Medications to treat inflammation in various infections? Sun Yuanqi's heart suddenly moved, and several familiar stories popped up in his head: "When it comes to drugs for treating infection and inflammation, I really have an idea. ”

Zhao Jinghui leaned forward, staring at Sun Yuanqi with big watery eyes: "Sir, you say!" ”

Sun Yuanqi said: "Modern medicine has proven that infection is a local tissue and systemic inflammatory response caused by the invasion of bacteria, viruses, fungi, parasites and other pathogens into the human body. As long as it can kill or inhibit the reproduction of pathogens with a certain effective substance, it can effectively fight infection and inflammation. So the key is to find this effective substance.

"A few days ago, when I was reading in the library, I found a record in a certain book, saying that in the Tang Dynasty, the tailors of Chang'an City would apply green hairy paste to the fingers cut by scissors, which could effectively help wounds heal and reduce inflammation. Jinghui, what can you find out from this? ”

"The paste with green hairs contains a substance that inhibits inflammation of infections?" Zhao Jinghui's eyes widened.

"That's right," Sun Yuanqi said, patting the table, "you have to pay attention to this, the text emphasizes that it is a paste with green hairs. In other words, the non-hairy paste has no effect, so the key is not in the paste; Green hairs, not black hairs and white hairs, indicate that only this green hair can have a certain medicinal effect. Do you know what to do? ”

That's right, Sun Yuanqi is talking about the miracle drug penicillin.

In the Chinese textbook, the scientist Fleming found the bacterium nemesis penicillin in a mustard petri dish with mold. But this is just a legend, a legend used by a successful scientist to coax the future to learn. However, the knowledge and use of penicillin by Tang Dynasty tailors was preserved in the notes of the literati as an anecdote.

Zhao Jinghui nodded quickly: "Same as artemisinin, analyze, compare, and purify!" ”

Sun Yuan smiled and said, "Correct! If an effective drug can be found to fight infection and inflammation, it will have a much greater impact than artemisinin. ”

Artemisinin is certainly a cure for malaria, but it is not irreplaceable. Prior to this, people had already discovered cinchona cream, but the side effects were a little bigger.

Originally, Sun Yuanqi counted on Artemisinin to win a Nobel Prize medal for Jingshi University. However, now that there is a patent dispute with Man Ledao, and Man Ledao is still an American, Zhao Jinghui's hope of winning the award is slim. In addition to the Peace Prize, which is specially awarded for the Nobel Prize, the Nobel Prize will also be used in various scientific and technological awards to varying degrees. The general rules are:

White and colored people found together, and whites won awards;

If there is a dispute between the teacher and the student, the teacher will win the award;

Democracies and autocracies produce results at the same time, and democracies win awards.

This is not a defamation dynamite award. Take the law of teachers and students as an example, streptomycin was developed by Rutgers University professor Sehrman? Waxman's student Albert? Saz was separated, and as a result, Waxman won the Nobel Prize in Physiology or Medicine in 1952, and Saz was not on the list. It was only through litigation that Saz was able to obtain part of the patent income for streptomycin.

Another example is the pulsar, one of the four major astronomical discoveries in the 60s of the 20th century, which was established in October 1967 by the Cavendish Laboratory of the University of Cambridge in the United Kingdom. Professor Hewish's graduate student, 24-year-old Jocelyn? Bell was the first to observe. As a result, Professor Heusch was awarded the 1974 Nobel Prize in Physics for the discovery of pulsars, but Bell was not mentioned.

Unfortunately, Zhao Jinghui is not only a person of color, grew up in an authoritarian country, but is also a student of Manle Dao, what are the odds of winning? But with the discovery of penicillin, the situation is completely different. Penicillin has been hailed as one of the greatest inventions of the twentieth century, and the "discovery of penicillin and its clinical effects" itself won the Nobel Prize in Physiology or Medicine in 1945. Even if the Nobel Prize Committee pretends to be deaf and dumb, it cannot turn a blind eye.

Of course, it is not difficult to discover penicillin in its clinical utility, and the key lies in how it is isolated and purified. Historically, in 1877, the famous French microbiologist Pasteur discovered that mold inhibits the growth of anthrax bacillus in urine. Fleming "discovered" the magic of penicillin again in 1928, but had to give up because the penicillin produced by mold under normal circumstances was very small and difficult to isolate and purify. It wasn't until around 1941 that Flory and Chin solved the problem that penicillin became popular. Fleming, Flory, and Chin also won the award together.

However, Sun Yuanqi is a traversal of the crowd, with a golden finger in his hand, which can easily solve this problem. β€”β€”In fact, for later generations, this golden finger is simply not worth mentioning, isn't it that radiation breeding leads to genetic mutations, which greatly increases the penicillin production of molds?

Zhao Jinghui said: "When I go back and put away the laboratory work, I will start this research immediately." ”

"This time, we have to eat a trench and grow wise, and do a good job of confidentiality!" Sun Yuanqi said earnestly.

Before Zhao Jinghui went out, he suddenly remembered something: "By the way, sir, when I came just now, Jing Fan asked me to tell you, saying that he had already thought about it and wanted to see you when he wanted to." ”

Sun Yuanqi remembered that he had an agreement with Jing Fan at the beginning of the year, and now it was almost time. He nodded immediately: "When you go back, let him come to the office to find me!" ”

Press the gourd to float the scoop! However, long pain is better than short pain, and now is the time to decide.