045-First Research Results
In the empty drug lab, the printer squeaks constantly.
Chen Chen's gaze left the electron microscope in front of the experimental table, and he stood up and exhaled a slight breath of turbidity.
As the plan gradually got on track, he finally had the capital to conduct research on NZT-48.
Thinking of this, Chen Chen picked up the printed experimental report and quickly browsed the research results of the past few days.
Drug Name: Unnamed.
Ingredients: C15H15NO2S, C9H13N, C23H21N6O3Cl.CH4O3S, C18H14Cl4N2O.
1. Molar refractive index: 44.09
2. Molar volume (cm3/mol): 161.5
……
5. Polarizability (10-24cm3): 17.47
Emmmmm……
Chen Chen showed a complicated expression.
NZT-48 is a drug that is produced after the compatibility of a variety of synthetic drugs.
In addition to some common compounds, it also involves multifunctional targeting molecules.
Among the components of NZT-48, Chen Chen found 2-[(R)-(diphenylmethyl)sulfinyl]acetamide, α-methylphenylethylamine, benzodiazepine? Chlortronidazolam, miconazole and other ingredients.
Miconazole ......
Chen Chen found many modern chemical formulas in it, such as modafinil, amphetamines, and even the ingredient of Dacrin???
Chen Chen deliberately checked on the Internet, and found a statement that miconazole is an effective new myelin regenerator.
In the study, miconazole demonstrated that miconazole can enhance myelination by inhibiting stem cell expression of cholesterol-producing enzymes, by searching the name: Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.
Of course, these research results are still only in the laboratory for the time being, and there is no real direction.
In addition, Chen Chen also found traces of N-pyridine-4-ylpiperazine-1-carboxamide, which can treat neurodegeneration.
Through the efficacy of several later drugs, Chen Chen can determine that NZT-48 has a part of the pharmacology, which should act on the myelin sheath of nerves.
The so-called nerve myelin sheath is a type of oligodendrocyte that is wound along the axons of neurons to form a composite cell membrane.
The main component of myelin sheath is fat, which is made by ganglion cells and forms a lipid sheath that has an insulating effect, can increase the transmission rate of nerve impulses, and has the effect of protecting nerve axons.
That is, in addition to proficiency, the speed of a person's reaction is actually determined by the myelin sheath of the nerve, and the thicker and more developed the myelin sheath of the nerve, the faster the person's reaction speed.
Vice versa.
In addition, Chen Chen also found various essential amino acids such as phenylalanine and isoleucine in NZT-48.
In other words, the NZT drug itself contains some nutrients needed for the high-speed operation of the brain, which did not surprise Chen Chen, but had a feeling of taking it for granted.
After all, you can keep your brain engaged in high-intensity exercise for 12 hours without enough nutrition.
However, for the time being, NZT-48 should belong to a standard neurological synthetic drug, as well as a brain metabolism and circulation improver, a arousal promoter, and a cognitive enhancer.
During this period of time, Chen Chen gradually figured out some ways through the testing of his body fluids.
NZT-48 has a certain neuroprotective effect, and its central excitatory effect is probably through the increase of glutamine synthetase, thereby reducing the production of γ-aminobutyric acid, and promoting the detoxification function and energy metabolism of nerve cells...... Right?
In terms of efficacy, the onset time of oral administration is about 3 minutes, the duration is 11~13 hours, and the blood concentration reaches the peak about 1 hour after oral administration.
The bioavailability of oral tablets is 90%, the total protein binding rate is 90%, the drug and its metabolites are excreted in urine and feces, and the apparent plasma clearance rate is 110~180ml per minute.
That's it for all the experiments.
Looking at this report, Chen Chen was not satisfied in his heart.
Because according to the course of the experiment, he only solved 30% of the components of the drug, and 70% of the components of NZT-48 are still unknown.
And if those ingredients are to be fully studied, it will not be achieved overnight.
If he really wanted to do research, Chen Chen needed at least a fully functional experimental center, a large team of more than 100 people, and astronomical experimental funds.
It seems that in addition to a power plant, Chen Chen has one more goal in the future.
Thinking of this, a smile appeared on the corner of Chen Chen's mouth.
Chen Chen not only did not become decadent and discouraged because of the obstacles ahead, but became more ambitious.
In other words, after taking NZT-48, Chen Chen will not have negative emotions such as decadence and discouragement at all.
After destroying all traces in the laboratory, Chen Chen climbed onto the laboratory table, reconnected several cameras with cut circuits in the corner of the laboratory, and then came to the roof in the middle of the laboratory.
Standing on the experimental table, Chen Chen looked around, then took out a lighter and aimed it at the fire vent.
Click!
A crisp sound rang out, and a faint blue flame suddenly rose from the lighter.
"Dididi!"
The smart chip of the fire vent detected the abnormal temperature and immediately issued a warning, and immediately, four or five nozzles in the entire laboratory sprayed a large amount of water like a goddess scattering flowers.
In an instant, the entire laboratory was completely destroyed, and all kinds of experimental instruments were powered off one after another, and then they were soaked in heavy rain......
Chen Chen wiped a handful of water stains from his face, turned around and left the laboratory.
As a result, as soon as he walked out, Chen Chen saw a large group of people rushing over from the office area.
"What's wrong, what's wrong? What happened? ”
A Mediterranean man with a group of security guards armed with fire extinguishers asked in a panic.
"It's okay, it's just that I accidentally triggered the arson alarm during the experiment." Chen Chen said indifferently.
One of the security guards rushed into the laboratory and walked out after making sure that there was no source of fire, and said in shock, "Manager, it's not on fire, it's just that all the experimental equipment ......"
The Mediterranean men and the others looked at Chen Chen sluggishly again.
"Don't worry, I'll pay for it."
……
Renting a laboratory from another company is not a long-term solution after all, and it seems that it is time to open your own experimental center.
On the way back, Chen Chen planned silently.
Then, he picked up his phone and dialed a number.
"Manager Xia, are all the things I need and my passport and visa ready?" Chen Chen asked.
"Chairman Chen, all the small things you need have been prepared for you and placed at your home." On the other end of the phone, Xia Yin Yin and Yang Qi said.
"Okay, I'll go back and see."
Without waiting for the other party to say more, he hung up the phone, and Chen Chen immediately drove his battery car back to the industrial park.
Back at the Blacklight Biotechnology Data Center, as soon as he entered the gate, Chen Chen saw a pile of goods piled up, with a passport and a Swiss business visa on it.
Chen Chen took out a pair of scissors, dismantled the goods, and then moved them to the door of the power distribution room.
"X, it's me." Chen Chen said to the gate of the power distribution room.
"Click."
The heavy door of the distribution room opened......