"Rebuilding the immune system?" Wang Wei looked confused.

"Do you know what is the most effective treatment for leukemia in the clinic right now?" Chen Chen asked rhetorically.

"Well, I haven't paid much attention to it, this should be biomedical knowledge." Wang Wei scratched his head.

"To put it simply, leukemia is a disease of hematopoietic stem cell lesions, and the body's hematopoietic stem cells have malignant proliferation for some reason, thus inhibiting the normal hematopoietic function of the human body, which is similar to the principle of cancer, so it is also called 'blood cancer'."

Chen Chen explained, "The most effective way to treat leukemia in the medical community today is to perform bone marrow pairing, select a volunteer with the most similar genes to the patient, and then the patient will receive chemotherapy and radiation therapy to kill the hematopoietic stem cells in the bone marrow." ”

"Volunteers are then injected with a drug called a 'mobilizer' that causes the blood cells in the bone marrow to grow in large numbers and release them into the bloodstream, which are then collected by the hospital and injected into the patient's body."

"Because the hematopoietic stem cells in the patient's body have been killed before, a niche is left in the patient's body, and the newly injected hematopoietic stem cells will produce an effect called 'homing', which will spontaneously enter the patient's bone marrow and rebuild the patient's immune system in one to two months."

Chen Chen concluded: "And this is called bone marrow transplantation, using the healthy hematopoietic stem cells of volunteers to replace the patient's diseased stem cells, in fact, the so-called bone marrow is not really bone marrow, but only hematopoietic stem cell transplantation." ”

"What does that have to do with your experiments?" Xia Yin couldn't wait to ask.

"My third experiment was to select a group of old and decrepit rats, clone them, and then extract young hematopoietic stem cells and mesenchymal stem cells from the clones."

"Then, as in the case of leukemia, the hematopoietic stem cells and mesenchymal stem cells of these rats are killed and replaced with cloned stem cells."

Chen Chen pondered, "If it succeeds, will this old rat regain its youth?" ”

"Shouldn't it be?" Xia Yin showed a shocked expression.

"Why can't it be?"

The corners of Chen Chen's mouth provoked a trace of curvature, "Mesenchymal stem cells have the ability to differentiate into various cells such as muscle cells, hepatocytes, osteoblasts, adipocytes, chondrocytes, and stromal cells. ”

"Why does the human body age? That's because of the functional decline of human muscles, bones, and internal organs, but why do human muscles, bones, and internal organs functionally age? That's because of stem cell aging. ”

"Young people's stem cells can continue to replicate, replacing senescent muscle cells, bone cells and visceral cells, so the metabolism of young people is much faster than that of adults, but when humans reach the age of 30, stem cells will age, and the speed of replication and replacement will gradually not keep up with the aging speed of the cells themselves, so the human body will also have traces of aging......

Chen Chen said, "So, if the human body's mesenchymal stem cells and hematopoietic stem cells can regain their youthfulness, can the human body also regain its youthfulness?" Even if other internal organs cannot be rejuvenated, even some body functions such as muscles, bones, and hematopoietic functions can be rejuvenated, which is beyond the reach of many people, right? ”

Hearing this, Xia Yin immediately showed a thoughtful look, after all, she is already a senior, and her knowledge is wider than Wang Wei, and she can understand better than Wang Wei what impact this experiment will have on the modern medical community if it is successful.

"If it really succeeds, this kind of result is enough to invest in the first district." Xia Yin showed a look of longing.

"I have contacted Meng'an Pharmaceutical Company, and I can use their channels to help us purchase experimental drugs, and I asked the price, which is absolutely fair and just."

Chen Chen added, "We can start the experiment today. ”

"Then let's go now." Xia Yin agreed, "Start the experiment early, maybe you can really complete the experiment in three months!" ”

The three of them immediately set off and took a ride to the building of Meng'an Pharmaceutical Company, while the Mediterranean man who had taken Chen Chen and Xia Yin to visit had also waited for a long time.

It's only been a few days, and the Mediterranean Sea above the Mediterranean man's head seems to be even more expansive.

"You are finally here, if you don't come again, the leader will scold me to death."

The Mediterranean man smiled bitterly, "I shouldn't have agreed to the condition that you start calculating the rental time after the winter vacation, and we lost more than a week in vain." ”

"Have you bought everything?"

"I bought it, I bought the head-mounted experiment recorder and all kinds of experimental drugs, and I have already helped you move to the fifth floor."

The Mediterranean man took out three magnetic cards and handed them to Chen Chen, "This is the laboratory access card, we will send someone to the laboratory to check once a month in the future, if there is damage, please compensate according to the price, I hope you can take care of our experimental equipment and do not pollute the experimental environment." ”

"Of course." Chen Chen took the magnetic card.

"And this." The other party took out a business card again, "This is the source contact person of our laboratory, if you lack experimental drugs and experimental animals, you can call this number to buy." ”

Chen Chen took the business card, which showed someone from the Shangdu Animal Experiment Research Center, and handed the business card to Xia Yin casually.

Because all the agreements had been signed before, after sending Chen Chen and the three of them to the fifth floor, the Mediterranean man said goodbye and left.

"The whole floor is your rented lab?"

As soon as Wang Wei arrived on the fifth floor, he wandered around, touching this and that with a new face, "This is too luxurious, it's better than the school's laboratory environment, by the way, where does the GMP laboratory come from, why didn't I see the entrance?" ”

"It's in the basic lab."

Chen Chen changed into disposable slippers and walked into the basic laboratory, "The blue alloy door in front is the entrance, and there are just two cubicles at the back of the basic laboratory, so I asked them to buy three beds and put them in it, which can be used as a lounge." ”

The two followed, and sure enough, they saw a large pile of items piled up in the basic laboratory, including three folding beds.

In addition, there are various encapsulated chemicals, which want to be transported into the clean area, and I am afraid that the three of them will be busy for a while.

As students of the School of Biological Sciences, it is not the first time for the three of them to enter the sterile laboratory, and the relevant procedures are still known, Wang Wei is responsible for transporting the drugs into the buffer corridor, Xia Yin is responsible for putting them into the transfer window, and Chen Chen is responsible for receiving them in the GMP laboratory.

As the three of them get busy, they can also divide their own labor for a while and do their own things in an orderly manner.

But before he could wait, the elevator door opened again, and a man walked in with a small cart of sterile boxes.

"This is what you call an SPF-level laboratory animal, right?"

"Yes." Wang Wei was responsible for delivering the medicine to the outside world, and immediately notified Xia Yin to come out to check the experimental animals and sign them.

The experimental animals, 60 SD rats and 10 experimental rabbits, were placed in the animal breeding room after a brief handover.