Chapter 331: In-depth Study
January 16, 3rd year of the new era.
The Spring Festival has just passed.
A Tianzhou spacecraft in a 7,000-kilometer orbit of Mars slowly braked nearby, and then maneuvered to change orbit to the 6,000-kilometer orbit of the Phobos satellite city.
Du Pengxin, a biochemical scientist at the former military's Rongcheng base, is the one who led the team to support Mars this time, and he has been engaged in biochemical viruses, X genes, and biochemical modification of human beings.
For the research and development of the fluorescent virus, the Institute of Life Sciences finally decided to send him over.
On the one hand, Du Pengxin's attainments in genes and viruses are not low; On the other hand, he has experience in organizing large-scale biochemical studies.
After arriving at the Phobos satellite, Du Pengxin entered the hibernation pod and activated the stand-in robot kept in the Martian outpost.
Huang Fan and Jiang Zhiren, who had been studying for almost half a month, took Du Pengxin to the biochemical experiment cabin.
"This is the Glowworm Virus?"
Huang Fan introduced: "This is the original strain of the fluorescent virus, and here it is the mutant strain. ”
Looking at the mutant strains in the more than 30 virus survival cabins, Du Pengxin's expression was slightly serious: "So many mutant strains?"
"There are a total of 37 species, all of which are symbiotic or parasitic strains, and in the freezer next door, there are 82 highly virulent strains." Huang Fan truthfully reported some of the situation.
As soon as he heard about so many mutant strains, Du Pengxin gradually became solemn: "The mutation speed of the fluorescent virus is too perverted, where did you collect the original strain samples?"
Huang Fan swiped his hand on the air in front of him, and a virtual projection map appeared in mid-air, which was a topographic map of the surrounding Greek basin.
"The red area above is the area where the fluorescent virus was found."
On the topographic map around the Greek basin, the red zone occupies about a tenth.
There are also some basic information of the fluorescent virus on the side, the original strain is 420~430 nm long, 60~65 nm wide, long strip-shaped, deep underground, can be semi-airborne (dust during excavation), and the common area is 20~50 meters underground in the semi-humid strata.
"When you dug up, you didn't cause a leak, did you?"
Huang Fan shook his head: "Don't worry, our collection management is all nanorobot disinfection to ensure that the virus will not leak out of the formation." ”
"That's good."
A group of researchers who came to support immediately devoted themselves to the research work, and Du Pengxin affirmed the research of Huang Fan and Jiang Zhiren.
The root of the Glowworm Virus is the terrible mutation speed, once it loses its mutation characteristics, the Glowworm Virus is also an ordinary virus.
……
Rows and rows of translucent culture media filled with countless deadly fluorescent viruses.
It only takes one strain to be put into Blue Star to cause an ecocide catastrophe in a short period of time, and it can complete the mutation in a few hours after being stimulated, and no vaccine will be used.
Huang Fan and others in full-body biochemical protective clothing are different, Du Pengxin and others, who came over with a stand-in robot, do not need protective clothing, and only need to be fully disinfected when they enter and exit.
"After knocking out the basal nucleus, these viruses completely lose their mutation characteristics, what a weird virus." Du Pengxin said as he observed the image.
In the virus culture medium, through the scanning of the atomic imaging scanner, these "castrated" fluorescent viruses can be clearly observed.
Although complex reproduction can be carried out, the mutation efficiency has decreased by thousands of times, and under the stimulation-induced mutation, the mutation efficiency is less than 1/10,000 of the previous one, which is no different from ordinary viruses.
On the other hand, those fluorescent viruses that have not been "castrated", even if one-third of the gene fragment is destroyed, as long as the basal nuclear fragment is still present, the virus can mutate.
Huang Fan, who was observing the genetic sequences of these viruses, suddenly discovered a feature.
As long as the 67 deoxyribonucleotide in the basal nucleus fragment is successfully combined with the human gene chain, that is, the deoxyribonucleotide does not change, the virus will form a symbiotic relationship with human cells.
He hurriedly recorded this discovery, and according to this discovery, he found No. 32 deoxyribonucleotide in the basal nucleus fragment, which determined the parasitic relationship of the virus; No. 55 deoxyribonucleotide, which determines the infection preference of the virus......
With the assistance of supercomputing, the functions of 112 deoxyribonucleotides in the basal nucleus fragment were preliminarily determined by Huang Fan.
……
In fact, there is a big difference between the deoxyribonucleotides of fluorescent viruses and blue stars.
Bluestar's deoxyribonucleotide molecule consists of three molecules: a nitrogenous base, a deoxyribose, and a phosphoric acid.
Deoxynucleotides are the basic structural and functional units of genes, and the part that determines the diversity of organisms is the four bases in deoxynucleotides.
They are: adenine (abbreviated as A), thymine (abbreviated as T), cytosine (abbreviated as C) and guanine (abbreviated as G).
These four bases are arranged in a different order and determine biodiversity.
But the fluorescent virus, or the four bases that the Martian microbes have, is not the same as the blue star organisms.
For this situation, Huang Fan, Du Pengxin and others had already expected it, because the bases and even the constituent elements of the X gene are very different from those of Blue Star Biology.
Convergent evolution under the rules of the universe can only determine the general direction of organisms, but not the details of organisms, which is the similarity under convergent evolution.
The four bases of Martian microorganisms are: adenine like (L), gyanpurine (J), subcytosine (Y), xanpyrimidine (H).
After identifying these bases and deoxyribonucleotides, Huang Fan and others, who had been busy for more than a week, finally started the first genetic modification experiment.
With the assistance of an atomic imaging scanner and nanorobots, Huang Fan replaced the purine of the No. 15 deoxyribonucleotide in the basal nuclear fragment with adenine-like.
Activated a small amount of radiation stimulation, the modified virus is still mutating at a high speed.
"Naoto, how's your situation going over there?"
"Failed." Jiang Zhiren shook his head and replied.
Du Pengxin, who put down the nanobot manipulator sensor, breathed a sigh of relief: "My side seems to have succeeded." ”
"Oh?" Huang Fan leaned over.
The deoxyribonucleotide 15 is the gene sequence responsible for virus replication, and Huang Fan and his team plan to control viral replication by modifying the base of the deoxyribonucleotide.
The experiment continued, and after figuring out the function of the gene sequence, they gradually confirmed the opening (dominant), closed (recessive), stress on (passive-semi-recessive), and association (with the bases of other gene sequences) of each gene of the virus through trial and error.
These experimental data and results have achieved the initial control of the fluorescent virus, which has laid a solid foundation for their further in-depth research.
Now, of course, they have only completed the basal nucleus, which only accounts for about one-twentieth of the genetic sequence of the fluorovirus.
They need to know more about all the genetic sequences of the original strain of the fluorescent virus so that they can carry out in-depth genetic modification.
Arbitrarily modifying genes without in-depth understanding is not conducting scientific research, but dying.
If the virus becomes more terrifying after the modification, it will be a shot in the foot.
Human beings need to believe in science, and they need to be in awe of science more than blind arrogance.