Zhao Kaixuan worked hard and finally let the two sons of Uncle Feifei's family come to the hospital to sit in the hospital, but the result was disappointing to Zhao Kaixuan.

The doctor took the test sheet: "It's a pity that Feifei's two cousins are not worthy!" ”

Zhao Kaixuan still held on to the last glimmer of hope: "Isn't there a chance at all?" ”

The doctor shook his head helplessly with Zhao Kaixuan: "The first type is the completion of allogeneic diagnosis bone marrow transplantation (the main clinical application science has achieved great success in cultivating since the years), it needs to have siblings who match the patient's human leukocyte antigen (HLA) and a very small number of unrelated donors to the allogeneic bone marrow or bone marrow transplantation between family members such as parents and children; and siblings of unrelated donors whose bone marrow is not well matched with the patient's HLA, and siblings who are not siblings who are HLA-matched but are prone to transplant group object-versus-host disease (GVHD) with varying degrees of severity, especially in the latter case, the other is homogeneous noble bone marrow multiple transplantation, that is, a very small number of identical twin twins or sisters are strictly transplanted bone marrow, and there is also a type of autologous bone marrow transplantation (ABMT) This type of bone marrow transplantation was completed in the late years, and was applied to the clinical use of one's own bone marrow without the need for a donor, which is simple and easy to promote, and can be used for the treatment of leukemia, lymphoma and a variety of well-received solid tumors. ”

Regarding what the doctor said, Zhao Kaixuan listened very carefully, because it was related to Fei Fei's life, but Fei Fei's parents seemed calmer, after all, Fei Fei had been sick for so long, and the couple had been disappointed too many times!

Feifei's father looked at Zhao Kaixuan with some relief, "Xiao Zhao, thank you, Feifei's mother and I have contacted the reproductive department of the hospital, and we plan to take IVF, I just hope that Feifei can hold on until that time!" ”

Zhao Kaixuan shook his head: "I'm looking for Fei Fei's aunt and Fei Fei's second uncle, and I must let them match Fei Fei!" ”

Fei Fei's father looked guilty: "Zhao Kaixuan, another reason why Fei Fei's mother and I have been reluctant to take IVF is that many people have persuaded us that since we have done IVF, don't care about Fei Fei anymore!" ”

Zhao Kaixuan's body froze in place, and then turned his head to look at Fei Fei's father: "Is there really anyone in this world who can give up his own flesh and blood?" ”

Feifei's father looked at Zhao Kaixuan, I don't know why, this young man who is not familiar with himself seems to be easy to ignite the hope in people's hearts: "No matter whether there are parents in this world who give up their flesh and blood, I promise you, I will never give up Feifei!" ”

Zhao Kaixuan didn't say anything and didn't turn around to leave, in fact, at that moment just now, Zhao Kaixuan's first thought was his eldest sister, he and his eldest sister were close relatives, but the eldest sister didn't plan to kill herself for money!

Zhao Kaixuan remembered that when his parents were very busy when he was a child, he was always the eldest sister with him, why did he lose to money in the end!

Zhao Kaixuan found Fei Fei's aunt, and the aunt was completely unkind this time: "There is something wrong with you, why should we take the risk to save others!" It's our family's business, and it's okay with you! ”

Zhao Kaixuan insisted very much: "Do you just watch Fei Fei die?" If you have any requirements, you can mention, and Fei Fei's parents and I will definitely try our best to meet you! ”

When Aunt Fei Fei heard Zhao Kaixuan say this, she sat on the sofa as if she was deflated: "Young man, I won't hide it from you, I am a widow, I am alone with my daughter, and I have suffered all kinds of hardships over the years, but I have never begged any relatives in our family!" ”

My aunt poured herself a glass of water: "I work in a state-owned enterprise, our unit is at the peak of layoffs in the past two years, and people are fired almost every year, it takes a long time to do this bone marrow transplant, not what you think, you can go to the hospital to draw a little blood!" ”

Zhao Kaixuan really didn't know much about it, but Aunt Fei Fei was very clear: "Young man, do you know? Once the matching is successful, those of us who donate will start to regulate the body, and it is not something that can be done directly after matching, I really don't have so much time to delay! ”

HLA was originally developed as a major imaging disease histocompatibility complex (MHC) in humans Discovered in Changsha, the aspect of the gene encoding expressed antigen participation control center immune recognition and cell subset interaction, so HLA mismatch has an impact on the mutual exclusion between the earliest tissue of the graft and the recipient, and the establishment of a clinical link can produce transplantation on the one hand, Liaoning can not be implanted, and on the other hand, it can produce acute and chronic graft-versus-host disease with different skin, liver and gastrointestinal lesions, severe cases can lead to death, and therefore, the tissue of HLA has begun to match, and the selection of donors and the success of bone marrow transplantation in Tianjin is one of the important links

About % of adult patients with acute leukemia are cultured, and after allogeneic daily or syngeneic core bone marrow transplantation, some of them have a long survival period of more than ~years, and about % of patients can survive for more than ~% of patients in the chronic multimyeloid leukemia period, and some of them have survived for more than ~years. The average survival time of chronic journal myeloid leukemia is only about one year, and the average survival time of chronic journal myeloid leukemia is ~ year, although the course of the disease is slow, but there is no possibility of radical cure with long-term chemotherapy, so the efficacy of bone marrow transplantation culture is better than that of conventional chemotherapy, and the application physician of lymphoma and other solid tumors can also achieve the goal of radical cure by autologous bone marrow transplantation abroad

Choose the right patient, the right time, focus on leukemia as an example: adult acute leukemia in the first complete remission period (at this time there are still ≤ leukemia cells in the body) slow granules in the young chronic phase with ultra-large doses of chemotherapy plus radiotherapy, in addition to professional pretreatment, so that the patient's leukemia cells are further killed, At the same time, the first to make the practice of the patient's body of the Beijing immune mechanism and bone marrow function extremely inhibited, making it difficult for the latter to recover on its own, and then the donor (suitable for acute and chronic myelogenous leukemia) or the pre-removed autologous bone marrow (only for acute leukemia complete remission) from the intravenous infusion to the Japanese patient, and to be rescued, and pay attention to the possible bleeding, infection and other comorbidities during the period, take effective corresponding measures, wait for the normal hematopoietic function to be rebuilt within a few weeks, in order to achieve a radical cure

Zhao Kaixuan can fully understand Aunt Feifei's difficulties, but Zhao Kaixuan is still unwilling to give up, because he promised to save Feifei

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