Luo Jia picked up the fountain pen that had been prepared, wrote on the whiteboard in the conference room, and wrote down many complex and mysterious codes, and the Wen brothers glanced at them and knew that they were genetic codes.

On the other side, Wen Chengfeng cleared his throat and began to summarize the recent work of the Department of Life Sciences, Luo Jia showed great trust in them, never urged the progress of the research, and did not even come to inspect once in a few months, but since Luo Jia has come this time, he must always report to the boss, which is also human nature.

"In the past six months, the biggest research achievement of the Department of Life Sciences has been to clarify some issues related to human lifespan, first of all, can human beings live longer?"

Wen Chengfeng glanced at Luo Jia, "The answer is yes, of course it is possible for human beings to have a long lifespan, because as we all know, our body cells are metabolizing all the time. ”

"Take the superficial layer of skin that women are most concerned about, keratinocytes take a total of 14 days from birth to death, and if you count the division cycle of 13 to 19 days, the entire cycle of skin metabolism is 41 to 47 days."

"Depending on age, there will be a difference in the speed of metabolism, with young people having a shorter metabolic cycle and older people having a longer metabolic cycle."

"In other words, it only takes 47 days at most, and our face is no longer the face of the past, but a new face through cellular metabolism."

"Of course, cell-level metabolism is a microscopic change, and from the outside, it seems that everything is still the same, but the cells that make up the epidermis of the face have changed a new batch compared to 47 days ago, which is also an indisputable fact."

Luo Jia nodded slightly, human beings are composed of cells, and cell renewal is going on all the time, standing from the perspective of cells, you yesterday and you today are actually not the same.

Wen Chengfeng continued: "The lifespan of liver cells is only five months, and then they will die, and they will be replaced, even our bones will complete a round of cell replacement every ten years, and after middle age, the bone renewal rate slows down, so osteoporosis is formed, so the elderly are prone to fractures after falling, and the fundamental reason is not that the bones become fragile, but that the metabolism of our elderly people slows down." ”

"It can be seen that if we can control the speed of metabolism, it is equivalent to opening the code of lifespan, and human metabolism is controlled by genes, what we are doing is to find and control that set of genes about lifespan."

"At the moment, the only way we know for sure is the right way to open up longevity, which is called calorierestriction, which simply means eating less, and every time you eat seven points full."

"We experimented on humans, on mice, on cells, on almost all species, by controlling the diet, reducing calorie intake, and in the end we succeeded..."

Wen Chengfeng introduced a lot to Luo Jia, from the past to the present, no matter how big or small, when he said that the laboratory has established eighteen standards for aging, Luo Jia nodded heavily, feeling that it was really a very correct decision to hand over the life science department to the Wen brothers.

Science is not child's play and requires rigorous, quantifiable standards.

Luo Jia forgot to see it in which network, mentioning a technology, life extension technology, how to extend life? Anyway, it just makes people look young.

Looks so young...

Hey, for this kind of idealistic subjective description, Luo Jia is really powerless to complain.

The specific items of this set of standards formulated by the Wen brothers are as follows:

1 glycoprotein.

2. Breathe hard in one second.

3. Arterial blood pressure.

4. Total cholesterol.

5. Reactive protein.

6. Creatinine clearance.

7 urea nitrogen.

8. Cardiopulmonary fitness.

9. Waist-to-hip ratio.

10 Proportion of maximum lung capacity.

11 Body Mass Index.

12. Leukocyte telomere length.

13 lipoproteins.

14 triglycerides.

15. Periodontitis.

16 white blood cell count,.

17 HDL.

18 apolipoprotein ratio.

This is the correct attitude towards science, in order to study anti-aging, they first used eighteen rigorous data, defined what is aging, along with this standard, there is also a set of algorithms and mathematical models, the personal indicators input, you can get the current aging coefficient.

"This is the current state of research in the Department of Life Sciences." Wen Chengfeng concluded: "We have done a lot of research, defined the criteria for aging, and found some organ-level metabolic control technologies, such as our metabolic management of the superficial skin, which has achieved quite good results, and the company's cosmetics department has swept the world, from the female consumers who love beauty, and achieved an astonishing amount of wealth, and this wealth has eventually become a space elevator, which has become our department's scientific research funding." ”

"To be honest, I was a little frightened that a woman was willing to pay such a high price in order to smooth out a few crow's feet at the corners of her eyes? This is not scientific! Isn't it just a few wrinkles, why are they so aggressive? ”

Listening to Wen Chengfeng's complaints, Luo Jia almost laughed out loud, up and down the company, the straight male atmosphere is too serious, the Wen brothers are all in their forties, and they are not young, but they are still upright.

Unscientific?

When was a creature like a woman ever scientific?

Luo Jia coughed lightly, stood up, and came to the whiteboard, "I already understand the specific situation, the life science department is doing a good job, in short, I can rest assured that you are one hundred and twenty." ”

"Next, I would like to talk about what I found in my spare time, since the development of distributed supercomputing and artificial intelligence, the threshold for scientific research has been greatly reduced, not only can I build my own models and do genetic deduction, but even junior high school students and primary school students who have some understanding of genetic science can also engage in research that they are interested in, and simulate genetic evolution and effective paths on supercomputing."

Huaxia's distributed supercomputing system is now becoming more and more awesome, the national network, computing power has risen wildly, has reached the extent that it is open to all individual users, and any Chinese citizen can use supercomputing resources to engage in scientific research.

Of course, there is still a big gap between the ideal and the reality, according to the statistics of the Supercomputing Administration, the largest application of the Huaxia distributed supercomputer system is game computing, and the second is CG rendering.

In other words, everyone didn't all do learning, but used supercomputing resources to develop games, as well as post-rendering for movies and anime, so that the picture of the small movie was clearer and moving, and the sound was more numb and trembling.

Luo Jia is not against games, he didn't play games less back then, the key is that games need to be graded and restricted, as long as young people don't indulge in them, play games for two hours a day, Luo Jia is not against it.

As for the small movie becoming clearer, Luo Jia didn't say it, in fact, he secretly praised it in his heart, high-definition small movies with panoramic VR are a good thing, who knows who watches it.

Luo Jia explained to the Wen brothers that he was engaged in life science research in his spare time, and if he came up with any scary conclusions later, you don't have to doubt it, it's not that I have anything special, it's all due to the popularization of supercomputing, and Luo Jia has always been very careful in covering up the truth about the golden dome.

Luo Jia pointed to a line of words he had written on the whiteboard earlier and said, "mammaliantargetofrapamycin, mammalian target of rapamycin, referred to as MTOR." ”

"MTOR is a class of threonine kinases, the C-terminus is homologous to phosphatidylinositol kinase, but it does not have the activity of esterase kinase, but the activity of protein kinase.

After listening to Luo Jia's opening, the Wen brothers were stunned for a moment and cheered up.

"Impossible! Could it be that Mr. Luo has found a genetic pathway that controls metabolism and autophagy!? ”

The Wen brothers shouted wildly in their hearts, they were all shocked, the gene signaling pathway is actually nothing new, as early as 1972, scientists discovered it.

To put it simply, it is to use protein kinase and phosphatase as signal transmission substances, and finally give orders to the cell, telling the cell that you should divide and proliferate, that you are already old, don't stand in the pit and don't, hurry up and calculate the ball, etc.

You can order your child to wash his hands before eating, but you can't order him to grow taller quickly, at least to 1.8 meters, and to have charming little eyes and long legs like the Korean Oba.

However, the gene signaling pathway can do it, because it can directly give commands to the cell, and the cell, which is calculated in tens of billions of cells, is the most basic unit of the human body, and changes in cells will eventually lead to global changes.

If the gene signaling pathway is so awesome, why don't we try to write about human genes to stop aging and make everyone grow long legs?

The reason is simple, it's just too hard.

The human genome map is composed of 25,000 genes and 3 billion bases, which is too large.

However, if you think that this is all there is to the human genome, you can only say that you are still naïve.

In addition to the above ones, there are more than a million genes of bacteria in the human body, because there are about a hundred trillion cells of other organisms in the human body.

In other words, 90% of the cells in our body do not actually belong to us, our body is actually composed of bacterial flora and some human cells attached to it.

In the process of hundreds of millions of years of evolution, our body cells and billions of microorganisms have coexisted, microorganisms have affected the evolution of each of our organs, including the brain and heart, and the DNA of microorganisms has already penetrated into the DNA of human beings, and the DNA of microorganisms has already become a component of human DNA!

It has been said that humans are the most complex beings in nature, and from a genetic point of view, this statement is not true.

Human genes are really complex, and it is almost impossible to find a path to completely control aging in such a complex genetic sequence, and even developed extraterrestrial civilizations can't do it.

The 2016 Nobel Prize in Biology and Medicine was awarded to the discoverer of the principle of autophagy, which shows that the research of earthlings in the field of genes is just in its infancy.

However, today, Luo Jia came to the Wen brothers' laboratory and brought them a gene signaling pathway that can control metabolism and autophagy, which made the Wen brothers tremble with excitement!

They can't believe what kind of shit luck can make Luo Jia accidentally discover a genetic signaling pathway that is likely to be controlled by aging when he was doing genetic calculations in his spare time!?

After the introduction, the Wen brothers were dumbfounded, Luo Jia put down the ink pen lightly and shrugged his shoulders, "Regarding the problem in the field of life science, I am a layman, but according to the results of the supercomputing model, the MTOR gene signaling pathway may eventually control the speed of cell metabolism and trigger cell autophagy." ”

"I pondered, if all the aging cells in the body were updated through the principle of autophagy, wouldn't it be equivalent to the I Ching in martial arts to wash the marrow and be reborn? It seems to be very funny, why don't you follow this genetic pathway and experiment a little? ”

Hearing Luo Jia's words, the Wen brothers stared wide-eyed.

Got a head?

If Luo Jia's model deduction is correct, the MTOR signaling pathway is not only a problem, but something big is going to happen!