Continuation of telomere repair in cells?

A hint of surprise flashed in Lu Yi's eyes, it has been more than two years since the birth of cancer suppressant drugs, and tens of billions of dollars have been spent on it in the past two years, but there has been no substantial progress.

The gene segment that determines the length of the telomere has been found, but until all the information of the human gene map is known, we do not dare to modify this segment of the telomeric gene by means of gene compilation.

Without changing genes, the method of supplementing telomeres only through the acquired has not progressed.

Because it is not less than ordinary trace elements or ordinary gene defects, such as a certain gene defect that causes a certain protein to be unable to be synthesized by the human body, it can be supplemented by oral or injection of this protein.

But telomeres are different, it is okay to say that it is a cellular substance, and it is okay to say that it is a gene carrier.

Telomeres are present at both ends of chromosomes, and its role is mainly to stabilize chromosomes and prevent end connections between chromosomes.

When the cell replicates multiple times, the telomeric length at the end of the chromosome will become shorter and shorter, resulting in the gradual instability of the chromosome, and eventually losing the ability to divide and replicate.

In other words, the lifespan limit is not caused by the chromosomal genes themselves, but by the telomeres that maintain chromosome stability.

Only stable chromosomal genes can divide and replicate, but the loss of telomeres leads to chromosomal instability.

Lu Yi flipped through the data and experimental ideas in his hand and looked at them for a while, and found that without the assistance of the system, he could not understand the data formulas and professional terms in these biological fields as a physics student.

Not wanting to waste points, Lu Yi had no choice but to ask Zhou Ying: "Is the continuation and repair of this telomere achieved through genetic modification, or is it an acquired supplement?" ”

"Fix it the day after tomorrow."

Zhou Ying explained: "This is inspired by the biological cloning technology of the Muba people, whose cloning technology does not require primary cells, but just a genetic map.

After obtaining the genetic map, their biotechnology can directly cultivate the corresponding primitive cell embryos, and then cultivate them into living embryos, and finally complete the cloning of life.

Primitive cell embryos can be cultured, and the telomeres contained in them can definitely be repaired and replenished. ”

"If the Muba people can repair and replenish, why is their lifespan not unlimited?"

Lu Yi raised a question, on the premise of not cheating with the help of the system, in the biological field, 0 of his stacks will be beaten by Zhou Ying.

"I don't know, this needs to be known through actual observation and experiments, and the natural lifespan of the Muba people is very long, 10,000 years, and they have less than 10,000 years from the discovery of genes to the demise of civilization.

Natural death is not a big threat to them, and their desire is relatively weak, so the need to increase life expectancy is not great, and the biotechnology left behind by the Legacy does not mention the idea of repairing telomeres. ”

Zhou Ying shook his head, the natural lifespan of 10,000 years is beyond the reach of human beings, you must know that human beings count tribal civilization, and it is only 10,000 years.

It is only when human beings are now generally only a hundred years old, and the lifespan is more than a hundred years, that there is such an urgent need to improve the life expectancy.

"Since it's the biotechnology of the Muba people, does that mean that other people can also know about it?"

Lu Yi frowned and asked another question, the technology tree left by the Muba civilization is shared by all human countries, although the establishment of the Human Federation is already a certain trend, but in the early stage it was still a national era.

There is still a big difference between such an exclusive telomere repair technology and a shared telomeric repair technology.

At least before the real unification of the Human Federation, this telomere repair technology can bring enough benefits to the Tomorrow Group and bring a greater leading edge to Huaguo in the future situation of the Federation.

"Unlike the Muba people, the biological cloning technology can use genetic information and then orientally cultivate the corresponding primitive cell embryos.

But what we want now is not to re-clon from embryos, but to repair them the day after tomorrow, although the technology involved in the two has a certain amount of figure-out, but the reality is still different.

If you want to achieve telomere repair, you must study telomeres in depth, and you must know the gene segments involved in telomeres. ”

Zhou Ying saw Lu Yi's thoughts, and said with a smile: "We have that gene replication theory, and it took more than a year to find the gene segments involved in telomeres in 3.2 billion base pairs through a large number of experiments.

Even if others have the biotechnology of the Muba people as the foundation, if they want to find the gene segment of the telomere, so as to achieve the acquired repair of the telomere, it will take at least a year.

In one year, our telomere repair technology has been perfected and can be applied practically, so you don't have to worry about running out of money. ”

"Didn't you say that it would be repaired the day after tomorrow? Why are genes involved? Lu Yi frowned.

Until the human genetic map is completely deciphered, he is secretive about any modification of human genes.

Zhou Ying saw that Lu Yiyou had become a biological idiot, so she had to explain helplessly: "It is necessary to first determine the gene segments involved in telomeres, understand the generation mechanism of telomeres and the principle of shortening, and then combine with the biotechnology of the Muba people to make it possible to repair them, and it will not involve genetic modification." ”

"That's right."

As soon as she finished explaining, Zhou Ying seemed to think of something, looked at Lu Yi and said: "Telomere repair technology is complete, I need a lot of computing resources to draw a genetic map of human beings, if you don't agree to me, I will strike!" ”

Hearing the repetition of the mapping of human genes, Lu Yi's face suddenly darkened, and he subconsciously raised his hand.

"If you fight, if you beat me, I'll go home."

This time, Zhou Ying, who subconsciously coaxed Lu Yi when he saw Lu Yi raise his slap in the past, did not flinch this time, and muttered aggrievedly: "You are allowed to study gravitational waves, and I am not allowed to study the human genome map." ”

Although he knew that if he slapped it, Zhou Ying, who hid the trembling attribute, would give in nine times out of ten, but looking at her aggrieved eyes, Lu Yi still couldn't bear to do it.

"Xiaoying, do you know how much resources this will take? It's a bottomless pit. ”

"Gravitational wave research is not the same for human civilization now, it is a bottomless pit."

Zhou Ying still didn't back down, and said aggrievedly: "If I have money, I will study faster, and if I don't have money, I will study slowly, and I don't want you to be satisfied." ”

"It's not the same ....."

Lu Yi wanted to say that gravitational wave research and a complete human gene map were not worth mentioning at all, but he stopped as soon as he spoke, and said helplessly: "That's okay, when the space shading layer project is completed, and the group has money to spare, I will build a supercomputer for you, and allow you to draw a complete genetic map." ”

"Lu Yi, we can apply for resources from the state."

Zhou Ying also seemed to know what kind of project it was to draw a genetic map of human beings, and after being willful, she was also a little worried that her requirements would affect Lu Yi's planning.

"The country's main resources and energy are now spent on development, besides, is there a difference between the Tomorrow Group and the country now?"

Lu Yi shook his head, now is the period of competition between the three countries, everyone is speeding up their development and improving their prestige in the Human Federation in the future, at this time, it is undoubtedly an unwise choice to invest national resources in the bottomless pit of human gene mapping.

Gravitational waves are difficult enough, but the complete gravitational wave data plus a curvature navigation data is only one-tenth the price of the complete human genetic map on the system side.