"Okay, I'll take a look at the fax and go. Vertex "

After Gu Yanan hung up the phone, he turned around to find that there was an extra page of fax paper on the fax machine in the corner of the emergency office, and walked over to pick up the fax to see the details of the vaccination incident at Ponyville Central Elementary School.

On the morning of September 17, a hepatitis A vaccination team came to Xiaoma Town Central Primary School in Yuntai County to vaccinate the students.

At first, the vaccination was carried out in the classroom, but due to the chaos and disruptive teaching work, it was later changed to the playground of the Central Primary School.

It was carried out in order from the lower grade to the upper grade, and when the vaccination reached the third grade, the vaccinated students had their first case of disease.

The first patient's condition: Li Xiaoran, female, 12 years old, was in good physical condition before vaccination, no fever and acute infectious diseases, no contraindications to vaccination, received hepatitis A vaccine on the morning of September 17, 2 to 3 minutes after vaccination, dizziness, chest tightness, nausea, paleness, cold sweat, numbness of hands and feet and other symptoms, the vaccinator told him to rest, and injected epinephrine in the school's infirmary, the symptoms did not improve, he was sent to the local health center for treatment, and vomited once on the way to the hospital.

After the first case occurred, the vaccinators explained to the students, teachers and some parents present that this was just a general reaction, and there was no need to panic, and the vaccination continued.

Since then, five students with similar symptoms have appeared, which has alerted the school doctor and vaccinators.

Parents were immediately informed that vaccinated students should go to the hospital if they responded.

As of last night, that is, at about 10 p.m. on September 17, the number of cases increased to 23, of which two cases were transferred to the county people's hospital for treatment, and three more cases appeared this morning, on the morning of September 18, with a total of 26 cases, including 13 males and 13 females, with the youngest being 7 years old and the oldest being 14 years old.

Yuntai County has set up an on-site treatment leading group and a medical assistance team to stop the vaccination of the batch of hepatitis A vaccine, and 26 vaccinated people with uncomfortable symptoms have been arranged to Yuntai County People's Hospital for observation and treatment.

After reading the fax of adverse reactions caused by vaccination in Xiaoma Town Central Primary School in Yuntai County, Gu Yanan frowned slightly.

Gu Yanan's first reaction to this incident was, could it be that there was something wrong with this batch of hepatitis A vaccines?

However, the current vaccine management is very strict, since the occurrence of vaccine cold chain transportation problems and manufacturers about vaccine titer problems, vaccines have been inspected and approved at various levels before being distributed to various vaccination points, and the probability of counterfeit or shoddy or unqualified vaccines appearing on the market has been very small.

In any case, this batch of hepatitis A vaccine needs to be tested by a third party to confirm its quality.

In addition to possible problems with the vaccine, the nature of the event should be judged based on the specific clinical symptoms of patients with adverse reactions to vaccination.

Gu Yanan was thinking about several ways to deal with this vaccination reaction incident in his heart, and Lu Li finished the experiment and came out of the laboratory and returned to the emergency office.

Lu Li saw that Gu Yanan was packing up the suitcases and sampling boxes used on the scene in the office, and couldn't help asking, "Sister Yanan, are you going to have a mission again?" ”

"There is an adverse reaction after vaccination in the Central Primary School of Xiaoma Town, Yuntai County, Director Yang asked our emergency response office to assist in the investigation, and you should also go with me."

Lu Li glanced at the watch on his wrist, "It's almost noon, should you leave now?" ”

"Well, the matter is more urgent, and we will solve it on the way for lunch."

Wang Xiaoxiao also came out of the laboratory, and when she returned to the office, she found that Lu Li and Gu Yanan were going to the scene again, and asked, "Do you want me to go?" ”

Gu Yanan: "No, I can just go with Lu Li, you guys will deal with other things in the office, if there is anything that needs to be transferred, I will call you." ”

Wang Xiaoxiao happily made an ok gesture, "Okay, then you guys go to the scene, I'm going to have lunch." ”

After speaking, Wang Xiaoxiao patted Lu Li's shoulder again, who was packing up his things, "It's hard work, and I have to sacrifice lunch time again." ”

Lu Li: "It's not just lunch time, read the situation on the fax, but also work overtime at night." ”

Although Lu Li didn't have any intention of complaining, Gu Yanan still explained to the people in the office in time: "Regarding the problem of our overtime, I have applied to Director Yang before, and I can give us overtime pay appropriately, but Director Yang said that our center is currently short of funds, so there is no overtime pay, but we can take a vacation." ”

Zhou Jie in the emergency office also interjected at this time, "Overtime pay is not extravagant, and it is very good to let us take time off." ”

In the discussion between overtime pay and compensatory leave in the office, Gu Yanan and Lu Li had already packed their things, carried the sampling box downstairs, and drove the on-site flow shunting car to Yuntai County.

Yuntai County is located in the southwest edge of Lianhai City, adjacent to the next province, the county has jurisdiction over 15 townships and towns, a development zone, a total area of more than 1,700 square meters, a total population of more than 800,000, including 750,000 rural population, is a large grain and oil production county.

Pony Town is located in the north of the county, about 25 kilometers, with an area of about 80 square kilometers, a total of 33 administrative villages, 65,000 people, 30 primary schools, 3 middle schools, and about 7,000 students.

Yuntai County People's Hospital.

By the time Gu Yanan and Lu Li arrived at the Yuntai County People's Hospital, it was already around 15 o'clock in the afternoon of June 18.

Staff from the Yuntai County Center for Disease Control and Prevention have conducted an epidemiological investigation on 26 patients with abnormal reactions to vaccination in the hospital.

Gu Yanan went to Yuntai County People's Hospital, first met with people from the local CDC, and then retrieved the medical records of 26 patients with abnormal reactions to vaccination.

The main manifestations of all children who have abnormal reactions to vaccination are chest tightness, dizziness, headache, fatigue, numbness of limbs, fever, etc.

Some hospitalized children have elevated cardiac enzymes.

Gu Yanan deliberately took out the medical records of patients with elevated cardiac enzymes clinically, and focused on their other examinations, and found that there were no objective indications for myocardial damage such as abnormal cardiac function, arrhythmia, abnormal electrocardiogram, and abnormal echocardiography.

The most important feature of all patients is that the subjective symptoms do not correspond to the objective signs.

All patients were between the ages of 7 and 16 years.

Gu Yanan initially deduced that the incident was a "mass psychogenic reaction caused by hepatitis A vaccination".

Gu Yanan first held an initial meeting with the staff of the Yuntai County Center for Disease Control and Prevention.

After Gu Yanan expressed his speculation about the vaccination incident at the Maverick Formation Central Primary School, the staff of the local CDC breathed a sigh of relief and responded: "After we conducted an epidemiological investigation of these students in the hospital last night, we felt that this was a mass acute psychohysteria reaction, that is, a psychogenic reaction, but the matter is serious and we can't rush to conclusions. ”

Gu Yanan was responsible for writing a report on the CDC team's investigation of the incident, which was sent overnight to the incident investigation team set up by the Yuntai County Government.

Although the CDC team has inferred about the adverse reaction to the vaccination at Ponyville Central Primary School, Gu Yanan is worried that the psychogenic reaction event will continue to expand if it is not handled well, so he stayed in Yuntai County People's Hospital to help with follow-up treatment.