Chapter 8: Mutant Bacteria
It turns out that Gu Yanan works at the CDC and is often interviewed by TV stations, so she has the opportunity to appear on TV stations, and this is how Nan Hanfei met her.
Nan Hanfei continued: "I have already answered a question from you, and for the sake of fairness, it is now my turn to ask you a question. ”
Nan Hanfei's tone was relaxed and humorous, and Gu Yanan smiled and nodded, "Okay, you can." ”
Nan Hanfei tilted his head and glanced at Gu Yanan, who was sitting in the co-pilot's seat, and then continued to drive, and after two seconds asked, "In addition to work, what are your usual hobbies?" ”
Gu Yanan was asked, she usually works in addition to work, in addition to the normal working hours of working five days a week, she often works overtime on weekends, if you have to talk about hobbies, reading is one, and occasionally she goes to the suburbs to climb mountains when the weather is fine.
Gu Yanan was hesitating, and Nan Hanfei followed up, "Is it difficult to summarize your hobbies?" Don't you have anything else to do but work? ”
"Hmm...... No, in addition to work, I usually read books, and if the weather is good, I also go hiking and exercising. ”
"I like to climb the mountain, I like it too, I know that there is a mountain in the suburbs that is very suitable for weekend climbing, the air is good, the mountain is not steep, there is no danger, not far from the city, only a dozen kilometers."
"You're talking about Yuntai Mountain?"
"Yes, it's Yuntai Mountain, isn't that the mountain you usually go to is there?"
"Well, yes."
"Coincidentally, I also like to go to Yuntai Mountain on weekends to climb and exercise, and I can make an appointment with him when I have the opportunity in the future."
"Okay." Gu Yanan didn't think much about it, and casually agreed.
Nan Hanfei asked again: "What books do you usually like to read, are they all books on infectious diseases?" You are an expert in infectious diseases, and you must have read a lot of books on infectious diseases. ”
Gu Yanan smiled and shook his head, "No, I only read those professional books when I was in school and work, and I read prose or novels most of my spare time." ”
"What type of fiction?"
"More sci-fi."
"Oh!" Nan Hanfei sighed slightly, "I thought that girls liked to read romance novels, but I didn't expect you to have similar hobbies to me, and I also like to read science fiction." ”
"Really? I thought the police would read some detective mystery novels. ”
"My daily job is detective reasoning, and I always want to take a break from my brain in my spare time, and science fiction novels are very suitable."
"Well, in line with my thoughts."
Gu Yanan and Nan Hanfei chatted happily in the car, chatted about their personal hobbies, talked about everyone's work, and finally talked about Gu Yanan being slapped at the entrance of the hospital this time.
Nan Hanfei asked: "Do you regret slapping the family of the car accident victim?" ”
"Regret what?"
"I regret helping Wang Jianguo diagnose auto-brewing syndrome, this incurable disease is rarely known."
"I don't regret it, whether it's for Wang Jianguo or the victim's family, I never regret it, for Wang Jianguo and Wang Jianjun, I'm treating the disease and saving people, this is my duty as a doctor, for the family of the car accident victim, I'm finding out the truth, everyone has the right to know the truth, and only in front of the truth can everyone bear its real responsibility."
After a short silence in the car, Nan Hanfei said with a smile, "Unexpectedly, our two views on this are also very consistent. ”
"You think I'm doing the right thing?"
"Of course, in a sense, your work and mine are essentially the same, both are restoring a truth."
The two talked about this, and the feeling of déjà vu in Gu Yanan's heart came out again.
The car quickly arrived at the Marina Sanatorium.
Gu Yanan had Wang Jianguo's guardian's consent form in his hand, and it was easy to collect various specimens of Wang Jianjun and get Wang Jianjun's previous medical records.
After returning to the CDC with Wang Jianjun's specimens and medical records, and saying goodbye to Nan Hanfei, Gu Yanan received a call from Lu Li.
On the phone, Lu Li's slightly excited voice said, "Sister Yanan, I isolated a smooth Candida strain from Wang Jianguo's specimen, which is not a strain that should be found in normal intestinal flora." ”
"Okay, I'm already at the gate of the CDC with Wang Jianjun's specimen, and I'll go to the lab right away."
——
Lianhai Center for Disease Control and Prevention, Laboratory.
Gu Yanan changed into a lab coat and entered the P2 experimental area.
Lu Li is wearing a biosafety suit, operating in a biosafety cabinet.
Gu Yanan sat in front of the biological safety cabinet and left the experimental chair beside him.
Lu Li held a glass petri dish in his left hand, pointed to one of the smooth droplet-like colonies, and said to Gu Yanan, "Sister Yanan, you see that this strain is a typical colony form of Candida glabrata. ”
"From the morphological point of view, it is Candida glabrata, and it is necessary to do a biochemical experiment to determine its biochemical characteristics."
"Understand, do the enrichment first, and then do the biochemical experiment."
"You can do the biochemical experiment of this strain of Candida glabrata, especially pay attention to its alcohol production experiment, I want to use it to do a genetic analysis, compare it with the genome of the intestinal flora, if he is the causative agent of Wang Jianguo's auto-brewing syndrome, then its gene will definitely have a mutation, we have to find this mutated gene."
"What about antimicrobial susceptibility testing? This is more meaningful for clinical treatment. ”
"Let Wang Xiaoxiao do the drug susceptibility experiment, and the three aspects will be carried out at the same time, and the speed will be faster."
"Okay."
——
According to Gu Yanan's arrangement, the three of them experimented separately.
Gu Yanan took advantage of Lu Li's enrichment experiment at the same time, Wang Jianjun's specimen was processed, and Candida glabrata with the same morphology was also isolated from it.
Within a few days, the results of the experiment came out one after another.
Candida glabrata isolated from intestinal specimens from Wang Jianguo and Wang Jianjun all had genetic mutations that were able to convert starchy substances into alcohol.
Alcohol is directly absorbed in the gastrointestinal tract, resulting in an abnormally high alcohol content in the patient's body although he does not drink alcohol, which is also the pathogenesis of auto-saccharomycetry syndrome.
Antimicrobial agents were also found against this genetic mutation of Candida glabrata, which produces alcohol, through antimicrobial testing.
Gu Yanan fed back the results of the CDC's experiment to the hospital.
Wang Jianguo's attending doctor changed the antibacterial drugs according to the results of the CDC's experiments, and Wang Jianguo's symptoms of auto-brewing syndrome were quickly controlled.
At the same time, Wang Jianjun, who was in the coastal sanatorium, also changed the treatment plan, which was also effective.
Although Wang Jianguo was criminally responsible, considering that Wang Jianguo suffered from auto-brewing syndrome and that he did not know that he was suffering from this disease before the accident, the court dealt with it lightly and assumed the corresponding civil liability for compensation, and sentenced him to several years.
The sensational Lianhai City cross-sea bridge car accident case is settled.