Chapter 9: Academic Boasting#
Qi Min was eating takeout after going offline, when he heard footsteps at the door, and turned his head to see Chen Linyou and Wang Xin coming back.
The two freshmen saw Qi Min in the laboratory this time, but they were no longer restrained: "Yo, senior sister, what about eating takeout?" ”
She didn't have any problem with this way of calling the boss of her laboratory "senior sister", so she also responded: "Yes, the cafeteria is not human." ”
"Really, the cafeteria is too crowded." Wang Xin leaned over and looked at the contents of Qi Min's bowl, "Senior sister, what is this?" Is it delicious? ”
Qi Min glanced at the receipt: "This is called...... Dolan Cooking. It's okay, it's just that the oil is a bit big. ”
"Senior sister, what are we doing in the afternoon?" Wang Xin then asked.
Qi Min was a little strange, didn't she say that she wanted to learn Python? Is it just a good idea to have lunch and you're done? "Have you two read Python?"
"Oh...... That's it...... Isn't it possible to learn from the library? Wang Xin asked a little confused, "Are there no experiments in the laboratory?" ”
"Your passaged cells will not be seen until they have grown overnight." Qi Min said calmly, "Our bioinformatics laboratory generally doesn't do wet experiments all day long, and there is still a lot of work to process data and write code. ”
After she said that, the two first-graders obediently returned to their seats to Python. Because they were already PhDs, Qi Min didn't assign them specific study tasks, but just sent them an email telling them that they were going to have a small meeting on Sunday to check how well they learned the language.
——
After that, Qi Min opened Jupyter again and took a look, the generation code of the full-size brain-like body was normal, and it was occupying 35% of the computing resources in the "rain cloud" at this time.
Qi Min's brain-like project uses dynamic allocation of computing resources in the "Nimbus" supercomputing center, and the computing resources allocated to her are theoretically unlimited, but they have to be adjusted according to the use of "Nimbus" by the computing center research team at that time. Although she cooperates with researcher Zhou Xiaoshan, "Nimbus" always has to give priority to meeting the needs of her research group.
Therefore, even if the total utilization rate of "Nimbus" computing resources has not reached half of the current level, because the research team of the computing center has prioritized the occupation of idle resources, the computing resources allocated to the brain-like project are only so much.
Of course, 35% of the "rain clouds" are already very fast, and the supercomputers that can really rank in the world are really not comparable to their own gadgets in college. However, Qi Min was still thinking that maybe she could find a way to get a little more computing resources, so that maybe she could re-submit the article before the Chinese New Year.
Qi Min was thinking about finding some reason to mention it to researcher Zhou Xiaoshan, as if he had a heart, and immediately received Ke Li's message on WeChat.
"How's your project going? Do you still need my number? Ke Li asked on WeChat.
Qi Min was a little surprised that he suddenly asked like this, and he didn't have a preface or afterword, but after thinking about it, he was afraid that something had gone wrong with his RNA structure prediction algorithm, and he needed her to "help each other".
"Teacher Zhou agreed with me to use 'rain clouds'." Qi Min replied, and continued typing, "Don't you have to run code?" ”
This time, it was Ke Li's voice call application that responded to her.
"What's wrong?" Qi Min picked it up and asked, "What's wrong with the RNA structure prediction algorithm?" ”
"Well, you guessed it all." Ke Li said a little embarrassed, "Actually, it's not a big deal, it's just ...... I took the company to do a sequence analysis of the deep sequencing and found some strange results. ”
"Send it to me." Qi Min said.
Ke Li sent a set of strange results from his run out to Qi Min from WeChat, Qi Min opened the compressed package from the computer, glanced at the dozen sequences, and didn't see a reason.
"What's wrong with these ones?" Qi Min asked.
"Wait a minute, I'm sending you structural projections." Ke Li said, "Okay...... Look at these things, why do they look so strange? ”
Qi Min clicked on his newly sent compressed package and opened the prediction result graph corresponding to one of the sequences. This RNA does look weird, in fact, some parts of it seem to be quite regular, but the rest of it is almost like it can't form a stable secondary structure at all.
"You're mRNA, aren't you?" Qi Min asked, "Did you forget to remove mRNA?" ”
"Won't you...... I'm using someone else's TRIM good data. Ke Li said hesitantly, "How to get rid of mRNA?" ”
"You just put the sequence MAP back on the genome, and then delete the part of the MAP that goes to the coding region." Qi Min said.
"Oh......" Ke Li agreed as if he didn't understand, and asked again, "But I should have removed the mRNA data, and the rRNA and tRNA have also been removed." ”
It is not an mRNA and should be a functional RNA, but the secondary structure is almost amorphous...... Qi Min suddenly thought, "You didn't go to the introns, did you?" ”
Eukaryotes have cleavage of RNA, and some functional RNAs can only function after shearing in vivo. Of course, there will be a difference in the secondary structure of the RNA before and after the shearing.
"Wait......" Qi Min opened a new PY file on Jupyter, imported the dozen sequences given to her by Ke Li, and used the existing gene MAPPING package to MAP them to the human genome, and sure enough, it was found that several of them were MAP to the same point, but some of them were missing these paragraphs, and some of them were missing those paragraphs, showing that they were actually the precursors of the same functional RNA at different stages of the shearing process.
Qi Min sent the results over, and Ke Li understood it at once: "Oh...... It turns out that these are all precursors. ”
It seems that although he is not very good at informatics technology, he still has a foundation in biology.
"Thank you so much...... If it weren't for you, I wouldn't really see what was wrong. Ke Li hurriedly thanked him, "That's right...... My structure doesn't take up much computing resources, and it's the same with the lab's own host to run code, or you can use my number as well - my boss is very generous to the people in his lab, and our lab's number can be used 5% first. ”
5% may not sound like much, but it is quite significant for the total computing power of the "rain cloud". And for the 35% that Qi Min is using now, 5% is also one-seventh.
"Then I'll use it generously." Qi Min said with a smile, "When the time comes, I will send SCIENCE, and I will have to start another line for you." ”
"That is, if I had published this topic in NATURE, I would have to thank you very much." Ke Li also smiled, "Etiquette is still exchanged." ”
"OR YOU WAIT FOR ME TO POST SCIENCE FIRST, AND THEN YOU SEND NATURE." Qi Min joked, "Let's stagger the publication time of this article a little, so as not to make it impossible for the media to report it." ”
Ordinary people are "academic boasting to each other", and their "academic boasting" is still quite fresh. The two first-year freshmen in the laboratory couldn't help but laugh when they heard Qi Min say this.
Qi Min hung up the WeChat call and joked to Chen Linyou and Wang Xin, who were sitting in their positions and laughing: "Don't be jealous of others. DON'T SAY IF I CAN POST SCIENCE, YOU GUYS ARE DOING A GOOD JOB IN THIS LAB, IF I REALLY SEND SCIENCE, THEN I WILL DEFINITELY BRING YOUR TWO NAMES. ”
"Thank you, Senior Sister!" The two new PhD students nodded immediately.
Wang Xin also joked: "Senior sister, you say it again, I have to record this as proof." ”
"What proof to make, I can write you a note directly, at a glance." Qi Min said deliberately.
This sounds very generous, but in fact, if you think about it, it is just a routine operation for the PI of the lab to post articles and bring students. Besides, after all, Chen Linyou and Wang Xin are also members of her brain-like research group, and they must be brought with them when the topic is published.