Chapter 442: Cloning Organs
June 20th.
After several days of consultations with Wang Zhiqiang, the Colombo side announced the completion of the "Friendship and Cooperation Agreement."
With Ceylon joining the Galactic Consortium, Tianhan Security quickly set up a security base in northern Ceylon and stationed the Sixth Mecha Team there.
With the establishment of this security base, the Galaxy Consortium has formed an area of influence in the northeast of Tianzhu Ocean.
In this way, the safety of the channel of the Galaxy Consortium in Tianzhu Ocean has been greatly improved.
……
Life Sciences Group, Hive Base in Australia.
Huang Haojie is operating a stand-in robot and visiting the laboratory.
There are people living in prison-like rooms, and these are death row prisoners and the like.
Through the one-way glass window, Huang Haojie observed these people, some sat numbly, some were yelling angrily, some looked idle, and some were watching TV series.
"How is the condition of the test subject?" asked Huang Haojie with an expressionless face to Kenji Takahashi.
"Chairman, there are a total of 32 test subjects, and all of them are in good condition." Kenji Takahashi didn't feel guilty about experimenting with these prisoners.
Huang Haojie glanced at the holographic file: "Why are there only 30 people left on the survival list?"
"Two of them committed suicide." Kenji Takahashi helplessly stalled his hands.
"Committed suicide" Huang Haojie was noncommittal, and then carefully looked at their experimental reports, because the cloning organ technology was very perfect, the cloned organs made by Takahashi Kenji and others did not find obvious rejection in the 32 experimental subjects.
The so-called rejection phenomenon is simply the exclusion of foreign tissues and organs by autologous tissues, which is a kind of rejection after transplantation.
Rejection is the rejection of substances that are not one's own. If blood type A is transfused into a person with blood type B, the body will produce antibodies with blood type B, which is the phenomenon of rejection.
Rejection often has very serious consequences, and in severe cases, it can be life-threatening.
In addition to blood transfusion, bone marrow, and even organs need to be transplanted, the biological indicators of the two must be extremely similar, and small differences may cause rejection after transplantation.
Milder rejection can be treated with medications, and immunosuppressants are generally used to combat this reaction, while severe rejection symptoms are often life-threatening.
The advantage of cloning an organ is that there is almost no rejection, because the genes of the cloned organ itself are exactly the same as the native organ.
For example, a person's lungs have lung cancer because of smoking for decades, and when the lungs are replaced, the body may not be able to adapt to this new lung, and rejection is possible.
Of course, this probability is quite small, and even if this rejection occurs, it can be eliminated through run-in therapy.
"Takahashi, you guys are doing generic cloning," Huang Haojie asked after flipping through the last part of the experiment report.
Kenji Takahashi nodded: "It's Dr. Michelle who is in charge of this, mainly to see if it is possible to clone non-prototype organs through other cells." ”
"How is the experiment" Huang Haojie didn't see the results in the experiment report, so he asked.
"There are some cells that can do it, such as stem cells, and there are some that are not fruitful for the time being, such as heart cells and brain cells." Kenji Takahashi replied.
The so-called universal cell cloning is to use any human cell to successfully clone any organ or part of the human being.
"Take your time, don't rush into quick success, what we have is time to study these things slowly." Huang Haojie said as he walked.
Walking and walking, the two of them arrived at the artificial blood laboratory in charge of Zhao Zhangde, Huang Haojie stopped Takahashi Kenji who wanted to be informed, and he walked directly into the laboratory.
Inside a clonal life support chamber, it was rapidly changing, and soon it turned a vivid blood red, but it was only red blood cells, and blood was made up of plasma and blood cells.
Plasma contains water, proteins, and low-molecular-weight substances, which contain a variety of electrolytes and organic compounds. Blood cells include red blood cells, white blood cells, and platelets. The average lifespan of red blood cells is 120 days, the lifespan of white blood cells is 9-13 days, and the lifespan of platelets is 8-9 days.
The lifespan of blood cells affects the retention time of blood, and there are generally two ways to preserve them:
The first is the lyophilization method [the various components in fresh blood are purified, and they are quickly lyophilized in a special machine, which can preserve the corresponding blood components for up to one year, and use a special thawing solution to dissolve them within the specified time and infuse them into the human body]
The second type of whole blood preservation [the kind used in street blood donation vans] is a special disposable blood preservation bag that contains anticoagulant ingredients and nutrient solution. Only one month of blood can be saved]
In addition, in addition to the main components plasma, blood cells, and genetic material, blood also contains various nutrients, such as inorganic salts, oxygen, cell metabolites, hormones, enzymes, and antibodies.
All of these things will have a certain impact on the research and development of artificial blood.
Zhao Zhangde, who was concentrating on the experiment, did not notice that Huang Haojie walked in, and was still doing the experiment on his own.
They are creating artificial blood by cloning red blood cells, white blood cells, and platelets separately and then adding other substances.
After a while, Zhao Zhangde shook his head, and the guinea pig in his hand showed obvious rejection.
"Is it a matter of proportion, or is it something else?" Huang Haojie asked.
Zhao Zhangde was stunned for a moment and then said, "Uh...... It turned out to be the chairman, and we had some minor troubles, and this blood modulation ratio needed to be tested for a while longer. ”
"Is the rejection very serious?"
"It's not too serious, we have adopted the dry-freezing method, and we will soon be able to produce universal blood, but there are still many people's blood that cannot be used universal blood." Zhao Zhangde explained.
Because a small number of humans have panda blood, and these blood types are not cost-effective in terms of cost if the hospital has a standing stock, Zhao Zhangde and they hope to create a rapid blood production machine.
In this way, the rejection phenomenon of universal blood can be solved, which is not only a problem of panda blood, because even if the blood type is the same, if the blood is not its own, there will be adverse reactions if it is transfused.
If a rapid blood production machine can be developed, only a little blood needs to be collected from the patient, and then a large number of clones can be produced, so that the hospital does not have to spend money to preserve the blood, and the patient does not have to look for the corresponding blood type and worry about rejection.
"Is it that after the system is integrated, the blood produced is prone to component concentration differences" Huang Haojie knew the problem at a glance.
"Chairman Gao Jian, this is this problem, we are now discussing the relevant situation with the Computer Research Institute, hoping that they can pass a suitable operation modulation system, after all, if this kind of thing goes wrong, it may really kill someone." Zhao Zhangde nodded and replied.
Huang Haojie encouraged Zhao Zhangde and others, and went to visit Michelle's universal cell cloning laboratory, and her progress in this area was also so-so.
However, now that the cloned organs are almost practical, Huang Haojie has instructed the life science group to announce the cloned organs on a scheduled date and recruit volunteers who are willing to participate in the cloned organ transplant operation.