In the vicinity of Raccoon City, a small town in the central part of the country, there have been a number of strange murders in which citizens have been attacked by wild beasts and bitten to death by psychopathic murderers. Special forces went to investigate the matter .. S's Bulava team suddenly loses contact with the outside world. The standby Alpha team came to the jungle to rescue their comrades, but was suddenly attacked by killer dogs, and members Jill and Chris had to flee into a mansion located deep in the jungle. But the big room they are in is full of researchers who have been turned into terrifying zombies by mysterious viruses because of the failure of secret experiments. In order to get out of this hell on earth alive, the two protagonists and other surviving companions resolutely raised their weapons.

After a series of surprises, fears, and rage at Spencer's villa, Rebecca and the other surviving companions escaped and returned to Raccoon City to immediately begin an operation to expose Ambrera. But to everyone's surprise, Ambrera's power has infiltrated all areas of the city, and even ... S's headquarters also seems to have been eroded...... In this case, Maine: David Trapp of the Exeter branch arrives in Raccoon City and invites Rebecca Chambors, who has some expertise in biochemistry, to join him on a trip to Caliban Bay, a small town in Maine, where there appears to be a research facility for Ambrera. David's plan was to steal evidence of Ambrera's biochemical experiments from inside and make it public......

Leon, a young police officer who has just graduated from the police academy, has just arrived at the place where he was assigned, Raccoon City, but there he is greeted by tens of thousands of terrifying zombies...... In this small city, where there is not a trace of human life, there are man-eating devils and fierce beasts that are frantically chasing their prey, and the dead who have awakened from the abyss of death move their slow steps, turning the city into ruins little by little. Although Leon struggles to escape to the police station, he is lucky enough to meet Ida Wang, a beautiful female art investor, and work with her to find a way out of this hell. But is this charismatic companion really just an ordinary investor? Or is it ...... What ulterior motives did she hide?

After learning that there was a codebook that allowed people who rebelled against Ambrera to hack into its core system, the former... S members David, John, and Rebecca, along with their new companions, Leon and Claire, are determined to infiltrate Ambrera's massive experimental facility built beneath the Utah desert. But the cunning enemy splits the team into two parts, and both sides are in unexpected danger - battling brutal, ferocious synthetic monsters on one side and an elite strike squad affiliated with Ambrera on the other. Will they be able to get their hands on the vital codebook and then safely join their companions? On the other hand, the true purpose of the mysterious man Trant is also revealed.

Ambrera sends a Resident Hazard Response Force to Raccoon City, surrounded by the dead, but the force is quickly disintegrated by hordes of zombies and betrayal by members of the Inside. Carlos, who survived, soon met Jill, a survivor who had escaped from a classified research facility, and the two decided to find a way out of this hell on earth together. But the rampaging and powerful bio-monster trackers stubbornly follow them and wait for an opportunity. On the way to escape, in addition to the overwhelming destructive tracker, there are also the traps carefully set by the cunning Ambrera, can they finally succeed in escaping?

Claire, who searched for Chris, unfortunately became Ambrera's prisoner and was taken to an isolated island at the southern tip of the Earth. But the island is soon bombarded by a mysterious force, which frees her, the T-virus, and Ambrera's strongest biological weapon. Claire, who narrowly escaped from the cell, and the young Steve's encounter, the two who were suspicious of each other at the beginning quickly cleared up the misunderstanding and decided to work together to escape from the isolated island occupied by death. And the descendants of Ambrera's founders, the crazy Asifort siblings, laid one terrible trap after another for them.

In order to hunt down the killers of a series of crazy murders that have recently taken place around Raccoon City,.. S's Bulava team was sent to the Akere Forest on the outskirts of the city to investigate, but the helicopter the team was traveling in crashed on the way to the investigation site. Although there were no casualties among the members, they soon discovered a strange thing: a military transport truck had mysteriously overturned on the side of the road - and this was only the beginning of their nightmare.

Chris rolled on its side, causing the monster's claw attack to fall on the wall, and the wall seven or eight centimeters thick was actually pierced with a large hole! He quickly got up and aimed his gun at the monster. Realizing that the attack had missed, the monster let out an angry howl and turned to lunge at Chris once more. But what it sees is the muzzle of a black hole.

Even a powerful shotgun would have to take three or four rounds to kill, and to add insult to Chris's headache, the monster had already flooded the entire mansion.

As for the monster's name, Hunter, he learned it in a file shortly after.

"More than half of the researchers have died from T virus infection, and almost all of the remaining survivors of this event have been reported to have been infected with the T virus."

"There is a high probability that the experimental species in the institute have fallen out of control, and the casualties are expected to increase further. But research data is more important than that, and action must be taken to avoid the results of research being made public. It is believed that the city government will send police and... S. entered into the intervention and strongly called for relevant countermeasures to be taken in response to the matter. ”

This is a report that Chris found from the underground research institute of the Western-style building. Previously, he had found several other suicide notes from researchers. In fact, it is not appropriate to say that the suicide note is not quite right, because these researchers are still alive. But they've turned into another life form – zombies......

It is worth mentioning that one of these suicide notes was written by a chief researcher named John to his girlfriend, and now Chris, of course, cannot know what the woman's name - Ida means.

After hours of searching, Chris has sorted out two important keywords for this incident.

. W (Organic Biological Weapon), T Virus.

And whether it is. W is still a T virus, and there is only one key word that connects them - Ambrera. All biological research comes from this syndicate ostensibly engaged in general pharmaceuticals. All sources tell Chris this.

The economic clout of the mega-multinational pharmaceutical conglomerate is like a web of influence in every corner of the world, and its subsidiaries control Raccoon City, the economic lifeblood of this small Oregon town, if not the de facto ruler of the city. But few people know that smuggling arms and developing biological weapons is their real job.

While reviewing the profile, Chris suddenly had the feeling that someone was standing behind him. He jerked around, but at that moment, the butt of the rifle slammed into the back of his head.

Before losing consciousness, Chris could see the attacker's face clearly.

It was a familiar face, though few had ever seen him take off his sunglasses.