Dr. Mingqi, the director of the Institute of Biochemistry and Biochemistry of the Pacific Base of the Interstellar Exploration Alliance, and the most prestigious life scientist in the entire IEA organization, is nearly 90 years old this year. Pen, fun, pavilion www. biquge。 infoIf it were anyone else, the 90-year-old might have already begun to recuperate. However, Dr. Minchi is a true scientific maniac, and to this day, he still insists on scientific research, and at the age of 90, he still stands at the peak of science.

When Yuan saw Dr. Minchi again, he was still wearing a white coat, thick round-rimmed glasses, and his gray hair surrounded his Mediterranean-style bald head, which looked both funny and intimate, exuding a very unique charm from the inside out.

"Hello, Dr. Minchi!"

Yuan Haochen greeted. Yuan Haochen has always admired Dr. Mingqi, a scientific senior.

"It's been a long time, Hao Chen-kun."

As he grew older, Dr. Minki's already deep voice grew deeper.

"You're still so energetic!" Yuan Haochen praised.

"Hohoho~~" Dr. Minchi laughed heartily, "I'm already an old man, what do you say is full of energy." ”

"You're serious." Yuan Haochen said modestly.

"Birth, old age, sickness and death, when the time comes, it will do. This is the law of nature, the normal condition of man. As a life scientist, I'm still very open-minded. Dr. Minchi said lightly, "The only regret is that I can't unlock the secret of you!" ”

"It's a shame." Yuan Haochen said slowly.

"Huo Huohuo~~, I thought I would be able to figure out the secret of your ageless appearance in my lifetime, but it seems that I can't do it." Dr. Minch sighed and continued, "Take a look at these samples. ”

"Good!"

Yuan Haochen didn't say anything, put on his white coat, and after various disinfections, followed Dr. Mingqi into a dark, fully enclosed laboratory, which was full of constant temperature cultivation systems.

"In the past ten years, I have cultured your tissue cells from generation to generation, and I have also conducted experimental research from different angles, and finally found a little clue."

Dr. Minch began to show his experimental data.

"A few years ago, I isolated the DNA (chromosomes) from your tissue cells, introduced them into other people's enucleated (no DNA) cells, and then cultured them. And guess what the result is. Dr. Minchi smiled and sold.

"How? Are you trying to clone me? Yuan Haochen smiled and threw the question back.

"Hohoho~" Dr. Minchi shook his head with a smile, "Within 50 generations, these cells will all die." ”

"Oh, it's back to normal human level." Yuan Haochen said.

"Yes, what keeps you young has nothing to do with the genetic material itself, or it is not the main factor." Dr. Minchi reasoned with a serious expression.

"Is it from the tissue cells themselves?" Yuan Haochen asked rhetorically, "But this is not very reasonable. ”

"Indeed, the root cause is not the tissue cells themselves, I suspect, it is an external force that has changed all this." Dr. Minchi added.

"External forces? What kind of external force? ”

A variety of possibilities came to Yuan's mind.

"The microcosm of life is as great as the macrocosm of the universe!" Dr. Minchi said meaningfully, "What is the chemical nature of biological matter?" How do these chemicals interconvert into each other in the body and exhibit life characteristics? What is the composition and structure of biological macromolecules? How do cells work? How do genes function as genetic material? What mechanisms promote cell replication? How can a fertilized egg cell use its genetic information in the singular process of developing into a highly differentiated multicellular organism composed of many very different types of cells? How do the various types of cells combine to form organs and tissues? ”

Dr. Minchi threw out a series of esoteric questions with great emotion.

"Science is great, life is wonderful!"

Hara smiled and uttered Dr. Mingqi's mantra.

"I think there's a mysterious, unintelligible force that activates the original superior gene fragment in your DNA genetic information." Dr. Minchi continued.

"The original excellent gene fragment?" Yuan Haochen asked with a little surprise.

"In the last century, the DNA double helix structure was elucidated, ushering in a new era of science and technology and opening a new chapter in the life sciences. Subsequently, the central law of genetic information transmission, genes and the regulation of gene expression were recognized. Since then, we have come to realize that the fate of the vast majority of living things is DNA and the genes it contains. ”

"However, the genetic information contained in the locks of human chromosomes is extremely large. At present, the biological community can determine about 23,000 genetic information about human beings (many lower organisms have more than humans, such as poplars have 100,000, and even roundworms are similar to humans, which hurts self-esteem too much.) ), which accounts for less than 10% of the total length of the DNA sequence. Is the vast majority of what is left just useless garbage? I don't think so, and many of the mysteries of human life may be hidden in these seemingly junk pieces of DNA. Dr. Minchi continued, with some certainty, "So, there are a lot of unknown genetic fragments in our genetic material that are good or bad that are not directly manifested. ”

Yuan Haochen also knows some of the relevant knowledge.

Although the source of some of the "garbage" in human DNA can be explained, such as the DNA of other invading viruses embedded in human DNA under a special mechanism, it is no longer active and has no effect. In addition, there are some organs that have been lost during evolution, such as humans who do not have tails, but the genes for long tails are still present in the human DNA.

However, Yuan Haochen will not think that this unmanifested DNA information is completely useless. Rather than calling them garbage, Hara prefers to call them dark matter in DNA (90% of this unknown DNA information is repetitive, and the repetitive sequences vary).

"Hao Chenjun, do you remember telomerase?" Dr. Minchi asked.

"Remember!" "The telomerase produced in cancer cells and germ cells repairs the damage that occurs at the end of the chromosome during cell division, so that the wound can be healed, and telomeres can be rebuilt after each division, so the tendency of telomeres to disappear during cell division is avoided." ”

"Yes, the gene that produces telomerase is found in all tissue cells in the human body, but why is it only expressed in cancer cells and germ cells? What is the hidden reason behind this? Dr. Mingqi's eyes widened, and he looked at Yuan Haochen and asked.

"Please advise!" Of course, Yuan Haochen didn't know the answer.

"Advice!?" Dr. Minchi was stunned for a moment, and hurriedly waved his hand and said, "I can't instruct, I can't instruct!" That's the ultimate problem that bothers me. Chaowen said, Xi can die! If I knew the answer, I would have no regrets in my life. ”

"So, it's the mysterious power you mentioned earlier that activates these sleeping genes?" Yuan Haochen asked rhetorically.

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(To be continued.) )