Xinghuo Life Science Research Institute officially launched human experiments on inducers.

The researchers of the AIDS program began to take the volunteers away according to the process established by Director Wang Xiaoxiao.

Wang Xiaoxiao keeps a close eye on the experimental situation of each researcher and solves possible problems at any time.

Seventy-two hours have passed since the volunteers were injected with inducer, and the project teams have developed steadily without a single death.

Wang Xiaoxiao felt relieved, the use of inducer hormone can basically be regarded as safe, as long as it can have a certain therapeutic effect, the AIDS project can be officially ended.

He walked first to researcher Ma Pingfang's lab.

Ma Pingfang is full of normal healthy people here, mainly to observe whether inducers can exist in healthy people for a long time and will not cause acute failure of organs.

As long as inducer does not cause rapid failure of human organs like deadly poisons, even if it has some side effects, it can be made into a drug for the treatment of AIDS.

Compared with the threat of AIDS to health, it causes a certain degree of liver and kidney damage, or persistent symptoms such as low-grade fever and high blood pressure.

It can be controlled with current medical treatments, and these side effects are much milder than other AIDS treatment drugs.

When Ma Pingfang saw Wang Xiaoxiao coming to his laboratory, his expression was a little cramped, and he said respectfully: "Director Wang, you are here, we are basically normal here."

Wang Xiaoxiao saw that the volunteers were all in the laboratory, they were not lying on the hospital bed, and they were all curious to use the VR smart glasses provided by the laboratory to experience the virtual world. Others are on the phone with their families.

Everyone's face was radiant with a healthy flush, and no one showed signs of organ failure.

Wang Xiaoxiao said with satisfaction: "Old Ma, tell me about your situation here."

Ma Pingfang's tone was clear, refined the key points, and reported: "Director Wang, I conducted a muscle allergy experiment before injecting inducer hormone into the volunteers.

It was found that the human immune system did not respond to it too strongly, and this is when the volunteers were officially injected with inducer.

A very small amount of 0.05 milligrams was injected, and the volunteer's blood was drawn every half hour to test his immune system and various indicators.

The volunteers found nothing abnormal, and I started injecting exactly half the dose of 0.5 mg in treatment.

After a period of observation, it was found that the lymph nodes were enlarged, the lymphocytes were abnormally differentiated, and the lymphotic T cells became very active, but the volunteers' bodies still did not have much abnormal reaction.

This morning for the 3rd injection of inducerin, I injected the normal therapeutic dose of 1 mg.

It has been observed for three hours now, and the spleen is somewhat enlarged, except for a more active immune system, and no abnormalities have been found.

Now it can only be determined that inducer does not cause an exhilaration of the immune system, which attacks the normal cells of the person at will.

Inducers are also also not hepatotoxic and nephrotoxic, and there are no abnormal changes in the liver and kidneys.

Through our observations, inducers can exist in the human blood and lymph for a long time, and the metabolic cycle is about 13 months. ”

When Wang Xiaoxiao listened to Ma Pingfang's report, he couldn't stop nodding, this situation was similar to what he predicted.

Human experiments in normal people have proven his pre-experimental inference that inducers have little to no damage to normal people.

He is a biological scientist, not an executioner, and he is not sure of it, and he will not apply for human experiments.

Wang Xiaoxiao didn't dare to guarantee that there was no problem with inducer before, after all, the human body is a complex biological system.

Modern medicine has not yet analyzed the specific components of blood, and inducers may not be able to react with some unknown components in the blood, but fortunately this very difficult problem has not arisen.

"Old Ma, you continue to make observations, always paying attention to the changes in the peripheral immune organs such as the spleen and lymph nodes.

Try to increase the dose within a safe range, and collect the maximum dose of inducer when it is safe. Wang Xiaoxiao solemnly explained.

He went back to Wu Minzhe's laboratory, where he was in charge of people living with HIV.

As soon as Wang Xiaoxiao walked into the laboratory, she met a pair of eager eyes.

When someone saw him come in, they boldly asked him questions.

"Director Wang, can you really treat AIDS?"

"Director Wang, I don't want your test fee, can you get rid of the HIV virus on my body?"

"Director Wang, I always feel like I'm dying, and I take care of myself like a porcelain doll every day, for fear that a virus will invade and my immune system won't be able to kill it."

Wang Xiaoxiao said in a soft tone: "You guys be quiet, we will inform you of the relevant situation after the experiment is officially over."

He saw that Wu Minzhe was also reassuring the volunteers, and he called Wu Minzhe out of the laboratory to ask him about the situation.

Wu Minzhe immediately reported: "Director Wang, we first conducted a small-dose experiment and found that the immune system seemed to be under command, and it was originally lymphotic T cells to deal with HIV.

With the participation of inducers, macrophages and lymphocytes also proliferate and differentiate rapidly.

Macrophages begin to destroy the HIV virus, and lymphoblasts rapidly differentiate into plasma cells, producing large amounts of antibodies to destroy the free HIV virus in body fluids.

At the same time, the rate of lymphotic T cell proliferation and differentiation increases exponentially, and the higher the dose of inducerin, the faster the growth rate of lymphoid T cells.

Now, just 72 hours later, the HIV in these volunteers has been cleared by 28% to 37%, and the rate of cleanup is related to the function of the individual's immune system.

When inducing hormone is injected, volunteers will develop signs such as a generalized low-grade fever and increased blood pressure.

If the inducer is used too much, the immune system synthesizes cells too quickly, and there will be related symptoms such as low blood oxygen and blood sugar, and lack of amino acids.

As HIV is eliminated in large numbers, sediment can also clog blood vessels, causing local blood clots.

The body's immune system is unable to cope with bacteria and viruses in the body, and other viruses multiply at a high speed. ”

Wang Xiaoxiao smiled and said with satisfaction: "It seems that inducer is very successful, the data you have collected is very good, make persistent efforts to observe the changes in the spleen and lymph nodes of the peripheral immune organs."

He ended up in Qi Zhenyue's lab, where she was in charge of volunteers who were already suffering from HIV/AIDS.

As soon as Wang Xiaoxiao walked into the laboratory, she heard the volunteers pleading.

"Doctor Qi, does your medicine have any effect, am I dying?"

"Doctor Qi, I feel like I'm no longer good, this is a dazed fever, nausea and vomiting, is it because the side effects of your medicine are too great."

"Xiao Qi, your medicine is really good, I always feel a little groggy in my body, I used your medicine, and found that the symptoms are much better."

Wang Xiaoxiao didn't want to experience the situation of being watched just now, so he immediately called Qi Zhenyue out to learn about the situation of inducer hormone on AIDS patients.

"I've heard from patients that our inducer has a strong effect on AIDS patients." Wang Xiaoxiao said in a more affirmative tone.

Qi Zhenyue shook her head with a wry smile, and said helplessly: "Director Wang, our inducer hormone can play a certain role in AIDS patients, if the human immune system is not too seriously damaged by the AIDS virus."

Inducer can stimulate the rapid proliferation and differentiation of mature immune cells in lymph nodes and spleen to control the disease of AIDS.

Through my observations, with careful medication, AIDS patients have the possibility of being cured and becoming long-term carriers of the virus.

But if the immune system has collapsed, the number of mature immune cells in the spleen and lymph nodes is very small.

This only stimulates the spleen and lymph nodes, overdraws the vitality of the immune organs, and causes a temporary increase in the function of the immune system, but it does not stop the progression of the AIDS disease. ”

"You continue to look at the data, especially for people with very severe AIDS. I now have a basic idea and will adjust the protocol in a moment. Wang Xiaoxiao said with a serious expression.

He already has a basic understanding of what inducers are like in the human body.

After Wang Xiaoxiao returned to the office, he began to adjust the direction of the volunteers' next experiments according to the human experiment data.

Especially for patients with severe AIDS, other adjuvant drugs are added to readjust the treatment plan.