211. DNA sequencing and sequencing are free to edit! (Tip plus 1)
"Yes, we're both from small islands."
The one who spoke was the oldest middle-aged man among the three, speaking the same as Chen Mengchuan, all of whom spoke the Chinese language of the island.
"Ahem, Chen, allow me to introduce me." Andrei hurriedly spoke.
Chen Mengchuan looked at him and nodded.
"This is Chen Mengchuan, the founder of Tianzhi Technology, and our biggest boss, I think you should all know each other."
"Chen, this is Shintaka Hanagata, this is Fujita Daisuke, both of them are from the island country, this is Xu Mingsheng, a native of Huaxia, this time our new project plan, the team of the three of them is the main object of cooperation." Andrei introduced seriously.
"Now, it's time to talk about your plans." Chen Mengchuan looked at a few people.
Several people looked at Xu Mingsheng, the youngest of all, and only he was the most fluent in Chinese.
Chen Mengchuan also looked at the man who looked about the same age as himself.
Xu Mingsheng took a deep breath and said slowly: "We hope to achieve perfect fast DNA sequencing technology through graphene technology. ”
Chen Mengchuan frowned, he didn't expect that their purpose was DNA sequencing technology.
To put it simply, DNA sequencing refers to the analysis of the base sequence in a specific DNA fragment, that is, the arrangement of adenine, thymine, cytosine and guanine.
Chen Mengchuan knows that DNA sequence knowledge has become indispensable knowledge in current basic biology research and in many application fields, such as medical diagnosis, biotechnology, forensic biology, biological systematics, etc.
The fast sequencing speed with modern DNA sequencing technology can help to achieve the sequencing of complete DNA sequences, or complete DNA sequences of many types of genomes and living species, including the human genome and many other animal, plant and microbial species.
It is not complicated, but it is full of uncertainties, and although this technology has been realized, it has been resisted by many countries, especially the European powers.
"Tell me about it." Chen Mengchuan said calmly.
"We started DNA research very early, and after the last time Dr. Andre and Dr. Konstantin and others completed graphene oxide tumor inhibition implants, we believe that graphene can do more. In biology, we believe that graphene will be the most perfect choice for bacterial detection and diagnostic devices due to its modified chemical function, large contact area, atomic size and thickness, molecular gate structure, etc......"
"Getting to the point." Chen Mengchuan frowned and interrupted him.
Xu Mingsheng didn't have any emotions because his words were interrupted, and after reorganizing his words, he spoke again: "We think graphene is a material with the potential for rapid electronic DNA sequencing technology!" ”
"We plan to make a nanohole with graphene that is about the width of DNA and let DNA molecules swim through it. Because the four bases of DNA, A, C, G, and T have different effects on the conductivity of graphene, we can know which base is swimming through the nanohole by measuring the small voltage difference that occurs when a DNA molecule passes through! In this way, we can achieve our goal! ”
"We need to make this graphene biodevice and then enable fast sequencing of electronic DNA, and once we can complete this technology, we ...... We ......" Xu Mingsheng said that he was stuck here, and he was so excited that he was a little speechless.
His words made Chen Mengchuan tremble, he knew what Xu Mingsheng hadn't finished.
Humans will have access to the technology to freely sequence DNA, and through a large amount of experimental data and DNA sequencing, humans will be able to evolve in a controlled manner and achieve unimaginable changes at the same time.
Chen Mengchuan's breathing became a little rapid, and he clearly felt that the blood in his body was surging up his head at a rapid speed, continuously delivering oxygen from the back of his ears to his brain.
After being silent for a long time, Chen Mengchuan opened his mouth and replied, "This matter ...... I need to think about it. ”
Chen Mengchuan felt his heart beating continuously, and at the same time, the blood in his whole body seemed to be boiling, and human beings freely wrote DNA...... It's really an unimaginable idea.
Because of Chen Mengchuan's identity, although several people wanted to speak, they all kept their mouths shut.
"Konstantin, you send the three of them to rest first." Andrei spoke.
Konstantin nodded, and quickly walked out of the office with the three of them.
Andre walked to the water dispenser and poured Chen Mengchuan a glass of ice water.
"Thank you." Chen Mengchuan took the water cup and drank the entire glass of ice water, feeling the cold from the mouth along the esophagus into the stomach, and the whole person was much more awake.
"Hoo ......"
The two walked over to the couch and sat down.
"A cigar?" André pulled out a humidor from the coffee table in front of the sofa, cut off his head, lit the cigar, and began to take small sips.
"Get me one." Chen Mengchuan nodded.
Andre put down his cigar, took another one, cut it off, lit it for Chen Mengchuan, and told him how to smoke it.
Chen Mengchuan in the dream is an old smoker, but he rarely smokes in this life.
The aroma of the cigar quickly spreads through the smoke, and the mouth is supple and not too choking.
The taste is unexpectedly good, this kind of smoky feeling, Chen Mengchuan has not experienced it for a long time, he doesn't buy cigarettes, and he doesn't have a habit of smoking.
"Tell me what you think, Chen." Andrei asked.
Chen Mengchuan glanced at him, slowly smoking the cigar in his hand, thinking about the complexity of this matter.
"Any life discipline will always come with a myriad of risks and doubts, but we can't stand still, can we?" Andrei spoke.
"We know too little about NDA technology, we only know and know DNA, but we don't know anything about the nature of DNA, we don't know and can't imagine that even if we complete the perfect DNA sequencing technology, we will really be able to achieve what we want, there are too many risks and uncertainties, and human beings have evolved little by little in tens of thousands, hundreds of thousands of years."
"No one can be sure of the impact of the changes that have occurred since we made our DNA freely. Can we afford these impacts? No one can answer this question. It's not a simple matter, Andrey. You know better than I do! Chen Mengchuan looked at him with complicated eyes.
André took a puff of his cigar and said slowly: "Frederick Sanger proposed DNA sequencing decades ago, and his dideoxy strand termination method has been ditched for more than 40 years, but even now it is still widely used, and the fluorescence automatic sequencing technology derived from it is based on his theory. It has been a long time since mankind made a new breakthrough in DNA technology. ”
"I also believe that sequencing and sequencing through graphene nanopores is feasible and controllable. As for the risks and concerns you mention, there really isn't anyone who can answer them. But because we know so little about DNA, we should try. Chen, you're by far the most suitable person to push for this, and I want you to think about it carefully. ”
Chen Mengchuan looked at the dark red light on the cigar and fell into deep thought.