Chapter 171: Telomerase

Xiao Li first visited the biologists, and after receiving a positive answer, he immediately lobbied them to give them to Aemond. Macaulay lays his hand. Pen, fun, and www.biquge.info

The process didn't go well, but with Xiao Li's three-inch tongue, they reluctantly agreed to give it to Aemond. Macaulay laid a hand, and gave Aemond. Macaulay didn't sit back either, promising to add the names of the scientists who had done it to the back of the inventor, and everyone was overjoyed.

A month passed under the careful study of scientists.

A lot of data appears on the computer.

These are research logs that don't have much value, but they don't mean they don't exist at all.

"Telomerase and free radicals?" Xiao Li handed a cup of coffee to his mouth, his fingers moved up and down a piece of experimental log on the keyboard slightly, and after a minute, he put down the coffee cup, grabbed the phone in his hand and made a phone call, "Help me call Jack. Dr. Southak came over. ”

Ten minutes later, Jack. Dr. Shostak sat opposite Xiao Li, he was dressed in a black suit, his black hair was neatly combed, and he was very energetic, "Xiao, are you looking for me?" ”

"Jack. Dr. Shostak. Xiao Li pointed to the experiment log on the computer, "In the experiment log, you said that telomerase and free radicals are the key to controlling the lifespan of the human body, what is the reason for you to make this conclusion?" ”

With this kind of affirmation in the ordinary experiment log, if it weren't for Xiao Li's daily reading of the scientist's experiment log, he wouldn't know that Jack. Dr. Shostak's confidence in his research has reached this point.

"Jack. Dr. Shostak. Xiao Li said: "I know telomeres, but what is telomerase?" Could you please explain. ”

"It's normal that you don't know, Xiao."

Jack. Dr. Saustarch laughed and said, "You're not a biologist after all, so it's understandable that you don't know anything about telomerase." ”

"In 1990, it was discovered that there is a hat-shaped thing at both ends of the nucleus of humans and some animals, which scientists call telomeres."

"In scientists' research, the older a cell is, the shorter its telomere length becomes; The younger the cells, the longer the telomeres. ”

"So they generally believe that telomeres are the key to controlling human aging."

"But over the course of decades, scientists didn't make much progress in telomere research until 2009, when three scientists discovered telomerase."

"Telomerase is a special enzyme that initiates telomeres, and the more active it is, the longer the length of telomeres; The lower it is, the shorter the telomere length. ”

"This discovery has been hailed in some small circles as the key to human immortality, and the three discoverers have won the Nobel Prize in Medicine."

"I remember correctly, Jack. Dr. Saustark's introduction is the Nobel Prize winner in '09, isn't it ....... Xiao had an idea, and he himself was taken aback.

"Yes." Jack. Schostak smiled and said, "Telomerase is me and Elizabeth. Blackburn also has Carol. Greid's joint discovery, when we won the Nobel Prize together. ”

"But ......."

Jack. Shostak paused, "We've fallen into a mistake. "We were approached by TA Pharmaceutical, and they offered us money to help us research anti-aging agents. ”

"In that study, we stimulated the telomerase enzyme in the mouse through tablets, so that the telomerase reverse transcriptase was revived, and the mouse also regained its youth, and even the male mouse has been reproducing offspring ......."

Jack. Saustak had a smile on his face, but it was quickly put away, "But there's a very serious problem here, so serious that our tablets are sealed. ”

"In the course of human trials, the process of reverse transcriptase caused some very scary symptoms in the human body." Jack. Shostak's body shook twice.

"Have you seen Resident Evil?"

"Resident Evil?" Xiao Li was stunned, "Does it have anything to do with it?" ”

It's just a movie...... Wait, Xiao Li's eyes sank slightly, a movie is not just that, "Interstellar", "Prometheus" and so on all prove that movies are more than just movies.

If Resident Evil takes place in reality, then .......

A shiver struck, and he couldn't imagine what a terrifying thing it would be if a Resident Evil happened in reality.

Doomsday is definitely not what some doomsday lovers think, close the door, bring enough food and water, and you can squat at home and be an otaku.

Loneliness is sometimes more terrifying than hunger.

"It's not as scary as you think." Looking at Xiao Li's expression, Jack. Saustar knew what he was thinking, "I said Resident Evil because some of the symptoms that appear in the human body during the reverse transcriptase process are similar to the zombies in Resident Evil, but they are definitely not the same. ”

"If it was the same kind, I'm afraid I wouldn't be here."

One ****** crime is enough to jail him for life.

"I'm sorry, I'm thinking too much." Xiao Li laughed dryly, "So what is he?" ”

"Abnormal changes in cells." Jack. Saustarch tried to speak in a calm tone, "The cells grew in reverse and many deformed organs grew, and in addition to that, there was an excessive need for energy, an abnormal craving for food, especially meat, and, in the words of the patient, hunger. ”

"It sounds like it's the result of an overdose." Xiao Li's brows furrowed fiercely, although he did not participate in the experiment, but from Jack. In Shostak's description he could see that Jack. When Saustak used the reverse transcriptase drug, it was so obvious that the patient had some problems.

"I thought it was at first." Jack. Saustak said in a deep voice: "But I reduced the drug, and the situation still did not improve, and even with a small amount of the drug, this symptom still occurred, and the reverse transcriptase experiment finally failed after three years." ”

Xiao Li fell silent.

Neither of them mentioned what happened to those experiments, that kind of deformed state, it was certain that they would be disposed of, he vaguely remembered that TA Pharmaceutical Company had announced that it would study life-delaying drugs, but then it disappeared, and he didn't care at the time, because there were too many companies like this kind of bragging, and even some well-known groups in the United States imagined the future and wanted to study fantasy technology.

Of course, these studies ultimately ended in failure.

But he didn't expect that there would be so many twists and turns in the process.

Reverse transcriptase works theoretically, but when applied to the human body, there are various symptoms, and the secrets of the human body are far deeper than what scientists have studied now.

"But ......." Jack. Shoseak's voice shifted, "The cells supplied by the base have shown me the reverse transcriptase method. ”

Jack. "Out of professional habit, the first thing I observe in the process of observing cells is the telomerase in the cells. ”

"After my observations, the telomerase contained in the cells provided by the base is different from the telomerase in human cells."

"Different?" Xiao was shocked and cheered up, "Oh, what is different for you?" ”

"How so......."

Jack. Shoseak pushed his glasses, "The base provides that the telomerase pot inside the cells automatically regulates. ”

Jack. Saustak drew a faucet in the air with both hands, "The telomerase is similar to a faucet, which can freely open and close and regulate the telomeres in the cells, so that the telomeres are in a constant state." ”

"It's like being intelligent, when telomeres get shorter, it stimulates telomere regeneration; When telomeres are too long, it can cause telomeres to age. ”

"It's like a constant regulator that keeps telomeres in a relatively normal state forever."

"My idea is to extract telomerase from cells and inject it into the human body, so that the human body can automatically adjust its state and keep it in a relatively normal state, which is not a very difficult thing for telomerase."

Bang Bang ......

Xiao Li applauded, "Very good idea." ”

He didn't know if the experiment would succeed, but there was no doubt that Jack. Saustak convinced him that the Nobel laureate was making a comeback after a defeat and that he felt good.

"You need my support?" Xiao Li sipped his coffee.

"Yes."

Jack. "I thought the idea of reverse transcriptase was wrong, but the cells at the base gave me new hope, and I wanted to try again and see if it would work," Shostak said sincerely. ”

"So I need your help."

If Xiao Li doesn't look for him today, he will also go to Xiao Li, this kind of idea, without support, cannot succeed.

"But there's a catch." Xiao Li said lightly, "Extracting telomerase from the cells will inevitably deplete the cells, what do you do to ensure that the telomerase will be successful?" ”

"You know, these cells are very precious."

Even he doesn't have much in his hands.

"And even if it's successful, telomerase still needs to be extracted from the cells, where do you get so many cells to extract telomerase?"

With so few cells and so many people who need telomerase, how can they be satisfied?

At that time, even if it succeeds, the dispute caused by telomerase can only be described as terrifying, and as for concealing the news, it is impossible.

When a person suddenly regains his youth, his relevant circles will definitely have doubts, and this kind of thing can be investigated clearly by just investigating.

At that time, I'm afraid it will be a bloody storm.

Xiao Li bet that the war surrounding him would not turn out to be much more merciful than the real war.

Jack. Saustak looked at Xiao Li, his mouth squirmed twice, and four words came out of his mouth, "Cloning technology." ”