6.37 The Forgotten Goddess of Darkness
is different from Suzi, who is attentive and listening to the conversation of the female doctor. Pen? Interesting? Pavilion wWw. biquge。 infoWu Chen is quite curious about the displays in the doctor's private laboratory. Every time Su Zi subconsciously swept the walls on both sides with the corner of his eye, Wu Chen would cheer up his spirit, see the right time, and search for these very private exhibits as much as possible.
The reason for this is also very simple, that is, to find clues that can determine her true identity from these items most directly related to the female doctor.
Through Wu Chen's unremitting efforts, there are still gains.
The first thing that is certain is that the female doctor is indeed proficient in ...... Human Genomics (=.=).
Most of the private exhibits hanging on the sides of the walls are fragments of the human genetic chain. These color-coded genomes obviously play a very important role in the inheritance of our lives. Wu Chen also found that the genomes on the walls on both sides were significantly different.
Well, the genome on the left-hand side is relatively simple and full of a natural beauty. The genome on the right-hand side is full of complexity and variety, as well as a sense of evil. Moreover, the set of genes on the left and right should be the same human genome and the mutated genome after the X mutation. One is the original appearance, and the other is the mutated appearance.
Wu Chen's attention even affected Su Zi.
The female doctor, who was talking to Su Zi, almost instantly gained insight into the distraction of this low-level researcher.
So the female doctor calmly interrupted the narration, and before Su Zi reacted coldly and was at a loss, she smiled appropriately: "Isn't it beautiful?" ”
"Yes." Suzi told the truth.
"That's the beauty of life." The female doctor seemed to recall something, but it was fleeting, and she regained her clarity: "I once imagined three models of DNA, and I called them: A, B, and C. ”
Wu Chen, who was preparing to bear a wave of spiritual shock, couldn't help but subconsciously smile bitterly: "ab...... c? "Please, I thought it was some kind of earth-shattering ghost and god, the code name that blew up the sky......
"Yes. It's ABC. The female doctor smiled and shrugged: "What else can it be?" Simple and straightforward, how nice. ”
"Yes, that's good." Feeling the master's resentment of the house, Su Zi in the spiritual connection with Wu Chen, couldn't help but smile.
"I thought I would come up with a classic chemical model. Molecules, molecular bonds, atoms, atomic bonds, ions, ionic bonds...... Then compose and a clear geometry. However, as it turned out, I was wrong. As it is said, the straight line belongs to the human being, while the arc belongs to the Creator. As she spoke, the female doctor took the calculation manuscript piled up in the corner of the table, revealing a double helix model full of infinite beauty.
The two beautiful spirals that are faintly separated, seem to be separated, and coil with each other are the arcs that belong to the Creator in the mouth of the female doctor.
"So Doctor, when you were studying the structure of the NDA, you designed three models?" Suzi grabbed her point of interest.
"That's right." The female doctor's fingertips caressed this double helix model as if caressing her own child: "The phosphate group forms the skeleton of two polynucleotide chains on the outer side of the helix, in opposite directions; The bases are on the inside of the helix, and they correspond in pairs, with adenine (a) always paired with thymine (t) and guanine (g) always paired with cytosine (c...... The base order of the two strands complements each other, and as long as the base order of one of the strands is determined, the base order of the other strand is also determined. Therefore, just use one of the chains as a template to synthesize and copy the other chain......"
With the female doctor's narration, a dusty memory from before Wu Chen became a shelter player was suddenly activated. Then borrowed Su Zi's mouth and blurted out: "DNA double helix!" ”
"Yes, the double helix." The female doctor looked up with a smile.
With a light touch of her eyes full of supreme wisdom, Wu Chen's whole body burst into flames: "Rosalindelsiefranklin (Rosalindelsiefranklin)!" ”
"You know me?" The female doctor's expression was a little surprised.
Just kidding, how could Wu Chen not know her!
Rosalyn Elsie Franklin - the true discoverer of the DNA double helix!
The forgotten goddess of darkness!
Rosalyn Elsie Franklin was a brilliant physicochemist, crystallographer, X-ray diffraction technologist, and geneticist.
He was born on July 25, 1920, in London to a wealthy Jewish family. Her uncle was the first Jew to enter the British Cabinet, her aunt was an intervener in women's suffrage and trade union activism, and her father was a professor at the London Workers' College, where he later became its president.
It's a Jewish elite, as the Jewish tycoons preach!
Growing up in such an elite family, Franklin has less of the arrogance of a rich girl, but more of the independence and desire for dreams of women in the new era. At the age of 15, she secretly decided to become a scientist, even though her father did not want her to pursue a path in scientific research. Because, in that era, there was more or less discrimination against women in the scientific community. But the stubborn Franklin still insisted on going on.
Let's take a look at her life from now on.
At the age of 18, she was admitted to Cambridge University from St. Paul's Girls' School in London. Three years later, although she successfully completed her studies, she did not get a formal degree when she left Cambridge University, but only had a "nominal degree" (decreetitular). This was only possible because at that time, the University of Cambridge did not award a "BAc" degree (bacantab.) to women.
However, gender injustice did not dampen Franklin's passion for scientific research. After graduating from Cambridge, she worked in the laboratory of Ronald Norrish (winner of the 1967 Nobel Prize in Chemistry). In 1942, as a result of the Second World War, she joined the British Coal Utilisation Association. In another three years, at the age of 25, she passed the defense of her doctoral dissertation and received a doctorate in physical chemistry. After the war, Franklin went to work in Paris, France. And at the National Central Chemical Laboratory in Paris, he worked for 3 years (another 3 years!). ), learn X-ray crystal diffraction techniques. It was there that some of Franklin's papers on coal studies made her internationally famous. For example, the application of X-ray crystal diffraction technology in crystal structure detection (Luobu placer powder crystal diffraction diagram).
In 1950, Franklin was hired to work at King's College, University of London. Her original research topic was supposed to be X-ray crystal diffraction of proteins, but her supervisor, the physicist John Randall, gave her a new assignment. At that time, the study of the chemical structure of DNA was a hot field. Whether it's a chemist, a physicist, or a biologist, they want to unravel the structural secrets of DNA as soon as possible. Under Randall's arrangement, Franklin began to study the structure of DNA.
On the basis of extensive research, three chemical structures of DNA are listed and named A, B, and C types.
In May 1952, after a long period of research, Franklin and Greens obtained an X-ray crystal diffraction photograph of B-type DNA, and applied the Patterson function, which was specially designed to solve the X-ray crystal diffraction problem, to analyze the picture.
The diffraction photograph, known as No. 51, was described by John Desmondbernal, one of the pioneers of X-ray crystal diffraction, as "almost the most beautiful X-ray photograph ever made." ”
And it is the No. 51 photo that clearly shows the correct structure of DNA and cracks the secret of DNA's structure!
However, however, what should have been her breakthrough discovery was stolen by several other male researchers (I won't name them) and used it as an important reference to develop a chemical model of DNA, the magical double helix!
The discovery of the DNA double helix structure is undoubtedly a milestone achievement in modern biology. So all kinds of honors and applause brought the two thieves to the world, but the real discoverer, Franklin, turned his heart to the study of TMV (tobacco mosaic virus). She led her team to complete the TMV mold, studied the infection of TMV to plants, the RNA encapsulated in the TMV protein shell, and the poliovirus, which causes polio, with a grant from the National Institutes of Health.
In 1956, Franklin felt unwell, and her abdomen swelled like a bag with a lot of water. After examination, doctors found that she had ovarian cancer, and she was only 36 years old at the time. Two years later, in April 1958, Franklin ended her short but illustrious life.
As a woman, she has always had a heart that struggles and is independent like that of men. She is extremely talented, and has made achievements in coal, DNA structure, X-ray diffraction, and virus research, but she has missed one opportunity after another because of the prejudice against women of the times.
She is in a "hostile environment, and if she feels confident and supported, she may have an amazing imagination" and the applause of the discoverer who belongs to the DNA double helix structure does not give her. The Nobel Prize in 1962 was only given to xx, xxx and xxxx.
What's more, in a certain thief's book "Double Helix", he once spared no effort to slander Franklin's image and achievements. and disparagingly called her "Lady of Darkness".
More books and articles about the double helix structure of DNA do not mention her name. In that era of male power, Franklin was more like the "dark goddess" behind the DNA, and almost no one knew she existed!
Of course, her untimely death was an important reason why she did not win the Nobel Prize. But if she is still alive, can she really win the Nobel Prize that should belong to her?
The answer is, no.
Because, she is indeed alive.
Standing alive in front of Wu Chen.
The reason why Wu Chen remembered her greatness was not only her great discovery - the most beautiful X-ray photo ever, but also her brilliance of personality.
She was so ostracized that she didn't even take a copy of her research with her when she left her DNA research position (mind you!). )。 Leaving them, including the "51st photo", to the male researchers who slandered, denigrated, envied, and cursed her. Even when they gained international fame because of this, she only smiled and was happy for the thieves from the bottom of her heart!
Oh my God, she doesn't care! (To be continued.) )