It was late in the evening, Washington time, and Ms. Cai felt like she had entered a strange chat room, one with a shabby layout, somewhat like a message board in the early days of the Internet in the '90s. Pen @ fun @ pavilion wWw. ｂｉｑUｇE。 ｉｎｆｏ

A dark green chat background, a sky blue chat message and speaking time, and a white cursor flashing behind her name, but strangely, she was the only one in the chat room. Yes, she waited in the chat room for a few minutes and never saw anyone else show up.

Faced with the dark green chat wallpaper, Cai Xiaoxi couldn't remember how she clicked here, as if she was searching for a paper on the latest treatment for Alzheimer's disease (AD) on the SCI website, and then inexplicably jumped out of this chat room interface.

"Is it a stranger's prank?" Cai Xiaoxi smiled, but she couldn't help but wonder about her name displayed in the chat box. The other party even knows her own name, isn't it a stranger, but someone she knows is joking with her?

Cai Xiaoxi searched for any of the friends she knew who would make such a joke with her, but after thinking about it, she found that there didn't seem to be such a boring person among her friends.

After hesitating, she was about to push out of the chat room when a paragraph suddenly appeared in the chat box. It was an abstract paragraph, to be exact, and it was related to a neurodegenerative disease she had just searched for.

Alzheimer's disease (AD), commonly known as Alzheimer's disease, is a well-known neurological disease, clinically manifested as neurological dysfunction, with more than 40 million people suffering from it worldwide, and no definite cause of the disease has been found, and there is no effective treatment.

Out of professional sensitivity, the mouse arrow controlled by Cai Xiaoxi hesitated slightly on the exit button.

At this moment, another text appeared on the screen.

"Due to mutations in amyloid precursor genes and progerin genes, β-amyloid (Aβ) is abnormally secreted and produced excessively, and is deposited in brain tissue, which has a toxic effect on surrounding synapses and neurons, causing the destruction of synaptic membranes and eventually causing nerve cell death. Therefore, the deposition of Aβ leads to other pathological changes in AD, which is the core link leading to the pathogenesis of AD. ”

"It's kind of interesting......" Cai Xiaoxi became interested in this sudden remark. Due to the limited number of words that can be displayed in the chat box, after reading this paragraph, she reflexively pulled the drop-down bar, ready to read the rest of the content.

"Amyloid precursor protein can be cleaved by α-secretase to form a neurotrophic substance APPSα under the normal pathway, but due to the presence of β-secretase and γ-secretase in the cell, the former will act on the 671 site of the amyloid precursor protein, and after cutting it, it will generate the N-terminus of Aβ, and then the latter will cut and process it at the site near 713-716, then Aβ40-42 will be generated, of which Aβ42 is the culprit of AD. At present, oral β-secretase inhibitors can be used clinically to block the production of Aβ42, and curcumin, a traditional Chinese medicine ingredient, can also inhibit the activity of β-secretase! ”

Cai Xiaoxi nodded slightly after reading this paragraph, which was closely related to her research, so it was easy for her to determine the correctness of this paragraph. But she also knows that in the past two decades, clinical trials have failed in clinical trials, whether it is by developing new drugs to eliminate Aβ plaques, inhibit Aβ aggregation and deposition, or reduce the production of Aβ in the brain by inhibiting the activity of β-secretase and γ-secretase.

The reason for the failure is not that researchers have misunderstood the cause of AD, but because once the match of Aβ is touched and ignites a pile of dry firewood, the subsequent combustion of dry wood will no longer depend on the action of the match, and even removing the match cannot prevent the burning of dry firewood.

At this time, a conversation would pop up in the chat box every once in a while, and Cai Xiaoxi's attention was completely absorbed by the content of the words, so much so that he forgot that he originally wanted to leave the chat room.

It wasn't until she finished reading all the content that Cai Xiaoxi woke up like a dream, she looked at the time and found that more than an hour had passed! She was immersed in the study for more than an hour!

"Who is the author of this research report, and if his research is true, it means that Alzheimer's disease, a neurological disease that has tormented mankind for countless years, has actually been overcome......"

Cai Xiaoxi's brows furrowed slightly, and she only felt incredible in her heart, and the candidates who might be the authors of this research report kept coming to her mind, but in the end, she ruled them out one by one. She got up and poured herself a glass of water, then sat back in her seat and continued to think.

After some time, she suddenly saw a link appear in the chat box.

Cai Xiaoxi clicked in curiously and found that the link pointed to an encrypted web page, and some questions appeared densely on this web page.

There are multiple-choice questions, true/false questions, and even answer questions, Cai Xiaoxi looked at it patiently, and suddenly had a feeling of irony, thinking that her dignified researcher and professor at the Institute of Biology of the University of Washington, doctoral supervisor, at this time actually answered the questions obediently like a student, there was really an inexplicable sense of excitement!

As if she saw the provocation of the questioner against her, and as if she wanted to prove her ability, Cai Xiaoxi's arrogant personality made her decision: "Okay, let me see how difficult these questions are." ”

She glanced at it and smiled disdainfully at the few topics on the homepage. These questions are very easy for her students to do!

It's just that as the questions continue one by one, she soon has some subtle changes, and she suddenly finds that the topics on the web page are actually from shallow to deep, and the difficulty is constantly increasing! From the beginning of the easy play, it gradually became difficult, so that there were many questions that even she herself was not sure of the answers.

Cai Xiaoxi gradually regretted it and felt that he should not be so careless. Finally finished the last solution question, at this time, the picture on the webpage changed, and there were hundreds of psychological test questions, such as:

If one day you do encounter a gangster robbing with a knife, and there are some items that can be used as weapons next to you, which one will you pick up to resist in a hurry?

Flags, chairs, knives, stones, umbrellas?

How old are you?

Gender?

Married or not?

Do you have children?

What do you usually do on weekends?

What are some of the most exciting/impactful parties/dates you've been to recently?

Etcetera!

In addition to these selective judgment questions, there are also some reflections on the degree, such as the feeling of the current situation around the phenomena and conditions: very satisfied, satisfied, average, dissatisfied, very dissatisfied; How you feel when you encounter something: really happy for others, completely unconcerned, maybe a little annoyed, slightly unhappy, really jealous, resentful with jealousy, angry, etc.

After doing more than 200 questions, Cai Xiaoxi already felt a little dizzy, and she even wanted to give up halfway, but when she thought that the previous hundreds had been done, she let herself endure it.

She didn't even think about the next many questions, and answered them directly by feeling, until one question appeared.

"If the earth is attacked by an alien civilization in forty-five years, are you willing to participate in the salvation of civilization and make your own contribution to the continuation of civilization?"

She clicked "yes", so the answer came to an abrupt end, and the follow-up questions did not jump out again.

"Wait, we're grading you!"

A dialog box popped up on the screen, and Cai Xiaoxi waited with interest.

A few seconds later, the results came in.

"Your valid grade for your major is 72 out of 100, and your grade is passing!"

"Your literacy grade is A+, and your grades are passing!"

"Your psychometric test has been judged by the system to be A- and meets the screening requirements!"

"You have been screened by this system and successfully shortlisted for the first batch of Science Seed Program of the Earth Fleet, please wait on the top floor of your current building at twelve o'clock tonight, and we will send a special aircraft to provide you with pick-up and drop-off services......"

"Hehe, a special aircraft to provide pick-up? What a clumsy joke! ”

Cai Xiaoxi shook her head, feeling how funny it was that she had spent so much time on this, she came back to her senses and found that it was already dark outside, and there was an immediate hunger signal in her stomach......

……

At the same time, the world, like Cai Xiaoxi, inexplicably entered the chat room, and then saw the cutting-edge scientific and technological achievements related to their majors, and inexplicably underwent an unknown so-called exam and psychological test.

Most of them, like Cai Xiaoxi, have successfully passed various assessments, but they basically take the sentence that pops up at the end of the page as a joke.

Zhou Chen asked Dandan to release a questionnaire to a total of 500 people this time, these 500 questionnaires are valid for one week, if you do not answer for more than a week, or do not receive the questionnaire for various reasons, it will be regarded as automatic abandonment, overdue and not waiting.

At night, the moon is in the sky and the stars are shining.

Cai Xiaoxi didn't know why she came to the top of the building, maybe she thought that the clear night sky tonight was too beautiful.

Just as she looked up at the starry sky, the clock crept past midnight.

A dexterous flying machine suddenly crossed the night sky, and then slowly descended in front of her under Cai Xiaoxi's stunned expression, opening the hatch to her......