Chapter 039: Pain-relieving mechanism

"Xiong Changlong," Zhou Rujun's voice changed, "What's going on?"

"I, I, I'll treat Dongdong right away!"

Xiong Changlong took out a round needle from the acupuncture bag as quickly as possible, and didn't even have time to burn and disinfect it with an alcohol lamp, just wiped it with a 75% alcohol cotton ball a few times, and pierced it into Zhao Dongdong's shoulder acupoint, and then his index finger formed a fishhook shape, hooked the needle body tightly, and used his thumb to stick to the needle handle, and quickly scraped down to relieve Dongdong's pain.

But more than fifty minutes ago, I tried an effective method, but this time it didn't work, Xiong Changlong's thumb was scratched more than 100 times, and Zhao Dongdong's screams did not weaken in the slightest.

If Xiong Changlong was only sweating on his forehead before, but now it was just over a minute, he was soaked with sweat all over his body, his clothes were tightly attached to his body, his shirt became transparent, and the whole person seemed to have just been fished out of the water.

Seeing this, Qian Fangzhao knew that Lao Xiong was out of proportion and couldn't let Lao Xiong continue.

"Dean Xiong, take a break!" he pulled Xiong Changlong away, and then said to a young doctor standing in the corner, "Shu Wenfeng, you go up, stop the pain first!"

Shu Wenfeng is the only doctor in Tianyang People's Hospital, graduated from the University of Melbourne School of Medicine, Australia, and is currently the director of the pain department of Tianyang People's Hospital.

He stepped forward to check Zhao Dongdong's situation, and knew that if he didn't deal with Zhao Dongdong, he would go into shock in pain, so he immediately issued a will to the nurse: "Ibuprofen suspension 17 ml, oral!"

Ibuprofen suspension is a common standby medicine at the nurse's station in the Gaogan ward, and the nurse quickly took it and gave it to Zhao Dongdong according to Shu Wenfeng's instructions.

At this time, Zhao Dongdong's screams did not lessen in the slightest, and his small body curled up in pain, and he might go into shock at any time.

But Shu Wenfeng didn't panic at all, because he knew that although ibuprofen had a pain-relieving effect more than thirty times that of aspirin, and he used an ibuprofen suspension that was more effective than ibuprofen sustained-release capsules, but with Zhao Dongdong's pain level, if other measures were not taken, it would take at least more than 20 minutes for the real effect to take effect.

How to make ibuprofen suspension work faster and stop Zhao Dongdong's shoulder pain may be a problem for others, but it is not a problem for Shu Wenfeng, a medical doctor who specializes in pain.

He grabbed Zhao Dongdong's left leg with his left hand, rolled his pants above his thigh, exposed Zhao Dongdong's left knee, stretched out his right hand, and found a protruding bone in the direction of the outer side of Dongdong's knee.

That's it, Shu Wenfeng screamed secretly, his right hand had become a vise-like and firmly buckled Zhao Dongdong's left knee, and his thumb pressed hard against the depression under the protruding bone.

It's strange to say, Zhao Dongdong's body, which was still tightly curled up in a ball, immediately relaxed, and gradually stretched out, although his mouth was still shouting, but it didn't have the heart-rending feeling just now, it was more like the aftermath of inertia. A few minutes later, the call in Zhao Dongdong's mouth turned into a chirp, and then the humming sound gradually became inaudible until it disappeared.

At this time, Shu Wenfeng often let out a sigh, let go of Zhao Dongdong's knee with his right hand, got up and reported to Qian Fangzhao: "Dean Qian, the pain has stopped, at least for 4 hours, there is no major problem." ”

Seeing that Dongdong no longer shouted pain, although Zhou Rujun's hanging heart relaxed slightly, but immediately a worry rose again, and asked Shu Wenfeng: "Doctor Shu, Dongdong is so young, will it affect his brain development if you give him such a large amount of painkillers!"

"Director Zhou, don't worry about this!" Shu Wenfeng said, "Ibuprofen is a non-steroidal antipyretic and analgesic drug, although it has a powerful analgesic effect, more than 16 to 30 times stronger than aspirin, but it is not addictive.

"Its analgesic mechanism is mainly achieved by inhibition of prostaglandins. Prostaglandins are related to pain, heat, and inflammatory reactions in the body, which can cause local tissue congestion, swelling, and fever, and amplify the "pain" signal, while non-steroidal anti-inflammatory drugs such as ibuprofen can inhibit cyclooxygenase (COX) in the body, and then inhibit prostaglandin synthesis to relieve pain.

"In addition to inhibiting the synthesis of prostaglandins, ibuprofen also inhibits leukocyte activity and lysosomal release, thereby reducing the pain sensitivity of local peripheral nerves to pain-causing substances such as bradykinin. It also helps with pain relief.

"Its pain-relieving mechanism is completely different from that of opioids such as morphine, so as long as it is within the safe dosage range, it will not have any effect on children's brain development.

"The safe dosage of ibuprofen is 10 milligrams per kilogram of body weight for six hours, and Zhao Dongdong's weight is 35 kilograms, so his maximum dose is 350 milligrams each time, with an interval of six hours. If it is converted into an ibuprofen suspension, it is 17 ml each time, taken every six hours, which is within the safe range. So you don't have to worry about the impact on Dongdong's brain development!"

Zhou Rujun didn't understand these pharmacology, looked up at Qian Fangzhao, and asked him for verification.

Qian Fangzhao nodded again and again and said, "Director Zhou, Shu Wenfeng is the director of the pain department of our hospital, and he is also a doctor of medicine from the University of Melbourne, Australia, and has a deep study of pain and anesthesiology, so you don't have to worry about the authority of his words." What we have to do now is to take advantage of Dongdong's pain-free time to immediately perform a CT enhanced scan on him to confirm whether Dongdong is really as the classmate surnamed Ren said, the shoulder pain caused by the liver abscess compressing the phrenic nerve!"

At this time, although the CT enhancement scan had not yet been performed, Qian Fangzhao already had some doubts in his heart that what Ren Jiangchi said might be true. Otherwise, it is completely unexplainable, Xiong Changlong, the most authoritative expert in the field of orthopedics and traumatology in Tianyang City, has made two consecutive shots, not only did not alleviate Zhao Dongdong's symptoms, but made Zhao Dongdong's shoulder pain worsen.

"You arrange it immediately!" Zhou Rujun said, "No matter how much it costs today, you must find out the cause of Dongdong!"

"Okay, let's arrange it now!" Qian Fangzhao waved his hand, and the doctors from the radiology department and the orthopedics and traumatology department were busy and began to prepare Zhao Dongdong for the CT enhanced scan examination.

Zhou Rujun couldn't intervene, and when he saw Xiong Changlong standing aside as if he had lost his soul, his brows furrowed, and he asked, "Dean Xiong, can you explain what is going on?"

Xiong Changlong shook his head in despair and said, "I don't know, and I don't understand why my method of setting fire to the mountain suddenly failed. Judging from the pulse, various imaging data, and examination symptoms, Dongdong has juvenile idiopathic arthritis! Now I can only wait and see, and after the CT scan results come out, there are no other new discoveries!"

Soon, the nurse had already done a test for Zhao Dongdong and proved that he was not allergic to contrast agents, so she inserted an intravenous indwelling needle in his arm and pushed him to the radiology department for a CT scan with contrast......