Chapter 448 Animal Experiment Base
Hermes was hospitalized again, his leg was saved, and after three to four weeks of rehabilitation, the external fixator could be removed, and in this way, the whole treatment was over.
Huang Jiacai was entrusted by Yang Ping and began to strategize, and he already had a mature plan in his heart.
First of all, a development limited company was set up in the name of Yang Ping, which is actually an investment company, focusing on investment in the pharmaceutical industry, and then planned to use this investment company to control Ruixing and control more companies in the future.
In this company, Yang Ping occupies 90% of the shares, Xiao Su occupies 10% of the shares, with a registered capital of 100 million, Huang Jiacai served as the CEO and legal representative, became Yang Ping's agent, and helped Yang Ping deal with business matters.
Huang Jiacai is ambitious, he has a grand blueprint in his heart, and then he will realize it step by step.
After Li Baosheng's surgery, other surgeries do not need to be done by Yang Ping for the time being, and Song Zimo and Xu Zhiliang can complete them.
Xu Zhiliang can't do difficult surgery now, but it is no problem for general surgery to operate independently, and it can be done beautifully.
In this way, Song Zimo's burden can be reduced a lot, and he can concentrate on difficult surgeries.
Taking advantage of his free time, Yang Ping took the time to go to Guilin, Guangxi, to inspect the laboratory of Xiehe in Guilin.
For the laboratory in Guilin, Yang Ping must have a detailed grasp of the situation in order to design animal experiment plans according to the conditions of the laboratory.
Nandu to Guilin, Guangxi, is very convenient, high-speed rail is only three hours, and the plane is not much time, not to mention on the road can also enter the system space laboratory to read books, do experiments.
Arriving in Guilin, Director He of the laboratory took the driver and drove a Haval H9 to pick up Yang Ping.
The laboratory is located in Yanshan District, Guilin, where there is a breeding base for experimental monkeys, and in order to facilitate the acquisition of experimental monkeys, Xiehe has set up the laboratory here.
"Professor Liang called me a few days ago and repeatedly explained that he must do a good job in reception."
Director He was very enthusiastic, and at the high-speed rail station, as soon as he received Yang Ping, he shook hands and grabbed his backpack.
Lao He is the director of the laboratory, used to work in the animal department of Guangxi Medical University, after the establishment of this laboratory, I applied to work here, this laboratory is not established, but the salary is much higher, and the work is interesting, which is very in line with Lao He's life expectations.
Before changing jobs, he also learned that this laboratory was set up by Concord and planned to exist for a long time, so he quit his original job and joined this laboratory.
Director He used to be a graduate of veterinary medicine, likes animals, and often studys, is an expert in laboratory animals, he is familiar with the procurement, breeding, and care of laboratory animals, and is also familiar with the production of most of the current medical models.
In addition to Director He, there are more than a dozen permanent staff members in the laboratory, plus rotating researchers, there are usually twenty or thirty staff members in the laboratory. In rotation, some are from Concord, some are from Hong Kong, and occasionally foreign researchers come over, and they generally stay for no more than three months.
Along the way, Lao He introduced the situation of the laboratory, and the Haval car didn't know how long it had been walking, and stopped in the yard in front of several small buildings, and there was a shed in the open-air parking lot, which could park at least ten cars at the same time, and the parking spaces were all drawn standard parking spaces.
Lao He pulled the car door and Yang Ping got out of the car.
These small buildings are very beautifully built, they are all three floors, the yard is very large, and the trees inside are tall and large.
"The front building is an office and dormitory, the second building is a laboratory, and the last building is a breeding ground for laboratory animals." Director He pointed into the distance.
Because the third building is far away, it is located on an artificial island, and a very wide and deep trench has been dug around it, and it used to be crossed by a bridge, which was locked by an iron gate.
"The young monkey you want, I have prepared, the scoliosis model has also been done, now it is difficult to find a monkey, the supply company, the person in charge is my classmate, I told them, no matter what, we must ensure the supply here, not that they complain, it is true that the supply of experimental monkeys is in short supply now, last time a company in the United States asked for 1,500, they refused, there was no way to deliver." Director He is very familiar with several large experimental animal farms in Guangxi.
Darwin said that humans evolved from monkeys, so monkeys are highly similar to humans in terms of genes, anatomy, immunity, physiology and metabolism, so it is very suitable for monkeys to be used for medical and biological research experiments.
Especially in the pharmaceutical industry, the dependence on monkeys is more obvious, and every drug has side effects, what are they? Carcinogenic, pathogenic, teratogenic, toxic, mutagenic, disabled, or even fatal? The best way to get data before it can be applied in humans is to get data from monkey experiments.
But not all monkeys are suitable for experiments, want to become experimental monkeys, need to meet a lot of conditions, the current commonly used monkeys are rhesus monkeys and cynomolgus monkeys, these two kinds of monkeys in anatomy, physiology, and humans are relatively close, is currently the most popular medical laboratory animals.
In Europe, it costs about 3,800 euros to raise a velvet monkey, and 15,000 euros for a relatively large macaque, but in China, it costs only 8,000 yuan to raise a macaque that can only be used for medical experiments.
The low cost of Chinese experimental monkeys determines that the price is even lower, which is a huge temptation for foreign research institutions and pharmaceutical companies.
This kind of monkey, which costs 8,000 yuan, can be sold for 12,000 yuan in the market, with a gross profit of 50%.
With such a large profit, there are naturally people who are willing to earn monkey money, and there are many "monkey raising" bases in China.
Guangxi, Hainan and other places are more concentrated monkey breeding bases, the breeding of experimental monkeys also needs professional knowledge, as a monkey for scientific research, not only need to be healthy, psychologically healthy, so their breeding conditions are very good.
"Now our laboratory has made a profit, not only to meet their own experimental needs, but also to make money, in our free time, we rent out some laboratories to some biomedical research and development institutions, do medicinal and toxicity experiments, charge by the day, a project charges as little as hundreds of thousands, more than millions." Director He was obviously very happy.
"I ate in the canteen at noon, there was a pig farm nearby, the boss was very familiar with me, I asked him to help go to the slaughterhouse to buy some fresh meat and pig offal, and then it would arrive, and the ingredients would be cooked as soon as they arrived."
Listening to Lao He's introduction, there are usually dozens of people eating in this laboratory, and the chef in the canteen is his wife.
Subsequently, Lao He took Yang Ping to visit the laboratory, which is not only fully equipped, but also very advanced, with an operating room, in which the surgical anesthesia equipment is very sophisticated, and even the extracorporeal bypass equipment is available, that is to say, it can simulate heart surgery.
"Scoliosis model, in the case of urgency, usually they are to remove the erector spinae muscles to make scoliosis model, Professor Liang said, the model made by this method is not suitable for your experiment, so we selected the experimental monkeys, this category will be eliminated, and the monkeys prepared are scoliosis caused by drugs in the embryonic period, so that the soft tissue structure of the entire spine is intact." Director He is very professional in these.
People who are interested in their work and have a sense of professional honor will definitely be able to do their job well.
"Our suppliers, other disease models are very mature, such as Parkinson's disease model, diabetes model, obesity model, middle cerebral artery occlusion model, hypertensive monkey model, kidney failure model, all of which are doing well, and they also have experimental monkeys that carry specific genes to build special models such as AIDS. However, for scoliosis models, they are not very proficient in making techniques, and I have to participate in the guidance every time, and the method of making my scoliosis model was taught to me by Professor Liang. Lao He talked eloquently, and when he talked about experimental animals, his eyebrows flew and danced.
The business of laboratory animals is also very specialized, for example, the production of these models requires special feeding or drug injections, so that monkeys suffer from the same diseases as humans, so as to study drugs related to the treatment of diseases.
The specific method has a high technical content, using drugs to make models, when to use drugs, what drugs to use, how many drugs to use, very particular, a high-quality disease model production, it is also not easy.
After visiting the laboratory, Lao He took Yang Ping to walk around the laboratory, which can be used as a tourist scenic spot with a little development.
At that time, the laboratory estimated that it had invested a lot, and the animal island alone was artificially built, and the surrounding isolation river and animal rest area were all very good.
The animal rest area has swings, slides, seesaws, wooden huts and more for these monkeys to play and play on a regular basis.
About lunch, Lao He received a call, fresh ingredients arrived, he entrusted the owner of the pig farm to get it, so he told the driver to drive to pick it up, told the driver not to delay, the ingredients in the cockpit, turn on the air conditioning, get the ingredients back and immediately hand them over to the kitchen, other ingredients don't matter, this pork offal should be fresh, make it delicious.
The driver drove the Haval out again, in fact, the traffic is very convenient, the road surface is cement, compared with the cement road in the countryside, it is much wider, or a standard two-lane.
Yang Ping is very relieved about the conditions of this kind of laboratory, if he didn't come in person, he didn't know the details, so he inquired in this way, and his heart was completely settled, and many animal experiments could be handed over to them in the future.
In terms of technology, there is no need to worry at all, Lao He and these staff are very professional.
The specific research work is all graduate students from Xiehe, and there is no problem.
A few young people came back in a pickup truck, Lao He said: "These are the doctors of Xiehe, they can play, after work, often go out fishing, today I heard that you are coming, I asked them to catch a few fish back, I don't know how the harvest is." ”
The young man parked the car, and there was a large bucket in the bucket of the pickup truck, and two people climbed up and carried it down.
"I'll take a look, it's good."
Lao He walked over with Yang Ping, and there were several big fish in the bucket, which made a splash.
"Send it to the kitchen." Lao He commanded.
"This is Dr. Yang!" Lao He remembered to introduce.
Several young people immediately greeted respectfully, they might be familiar with Yang Ping's situation, and they were personally recommended by Professor Liang, so several people seemed more restrained.
"Have you bought everything? Beer, beer can't be less. ”
Lao He shouted, and it could be seen that he usually got along well with these young people.
"This car is so dirty, go wash it." Lao He felt sorry for the car.
The young man drove the car to the side, picked up the tap, and began to wash the car.
"Look, what else will be needed for the experiment then, you just say."
Lao He took Yang Ping to read it and asked Yang Ping.
Each experimental project has its own specific requirements, and Lao He should prepare in advance.
"If you usually use monkeys for spine surgery, is there a spinal surgery position frame for fixed monkeys?"
Yang Ping just took stock, and he was short of this thing.
"Yes! There are several, in the warehouse. ”
Lao He knows the equipment well.
"That's good, our external spinal fixator experiment has not yet left the factory, once it leaves the factory, I will contact you, express it, we will do the external fixation surgery, you have to help be responsible for daily mediation." Yang Ping briefly talked about the division of labor.
Lao He said: "Well, in the afternoon, I have arranged time, you will give a lecture to everyone, and those doctors of Xiehe will be in charge of your project at that time." ”
In the kitchen, Lao He's wife sent a message to ask Lao He for help.
"You go and get busy, I'll go around by myself."
Yang Ping looked around in the courtyard of the laboratory, and several doctors came to talk.