Chapter 627: A Blank Piece of Paper
The strong self-confidence on Yang Ping's body is like a unique label, which Tang Shun can recognize at a glance.
At that time, this was the same in Tokyo, and this self-confidence made all the Japanese people lose their energy as if they were dehydrated, and there are still stories about Yang Ping and a cartoon about him among medical students at the University of Tokyo.
Following Yang Ping were Song Zimo and Xu Zhiliang, and Tang Shun was also very familiar with these two.
When he was in Japan, Tang Shun worked as a personal translator for them for a few days and became friends with them.
There were two foreigners behind him, if I guessed correctly, the young red nose was Robert, and the slightly older one was August.
Before returning to China, Takahashi and Tang Shun introduced these two world masters who studied with Yang Ping.
Of course, it was also Takahashi's idea to come to Sanbo to have a look, and Takahashi said that the future of joining Yang Ping's team is bright.
Even Takahashi knows the truth, how can I, Mr. Tang, not know.
It's just that in the eyes of my teacher Tang, a career must achieve two functions in order to be called a career, one is to realize the ideal, the other is to earn money, and one less is incomplete.
"Hello, Dr. Tang!" Yang Ping stretched out his hand.
Holding Yang Ping's hand, Tang Shun, who had always been confident, was a little flustered, he didn't expect that it would be Yang Ping himself who came to greet him, how could he make Takahashi and a group of men who were proud of Tokyo bow down to greet him.
However, Tang Shun's nervousness was superfluous, except for the confidence in his body, Yang Ping did not give him any sense of oppression, but a feeling of ease.
"This ---" Yang Ping didn't dare to casually conclude the identity of the girl next to Tang Shun, after all, the relationship between the characters now is complicated.
"This is my girlfriend, you can call her Chixia." Tang Shun generously introduced.
Chinatsu Suzuki, a first-year undergraduate at the University of Tokyo, bowed shyly, "Please take care of me." ”
---
General Surgery Yang Ping's office.
Everyone sat down, Yang Ping met friends with tea, and the aroma of Longjing wafted in the office.
Tang Shun's little Japanese girlfriend was accompanied by Tang Fei and took her to visit the hospital.
This little girl from the University of Tokyo said goodbye to Tang Shun in a sweet voice and followed Tang Fei to visit Sanbo Hospital.
After a few greetings, Yang Ping went straight to the point.
"Dr. Tang, we are currently launching a new project--- stem cell muscle cultivation, and we want to open up a new world in the field of organ cloning through this research, and we are interested in inviting Dr. Tang to join us."
Song Zimo has already chatted with him many times on WeChat, and there is no need to do any foreshadowing.
"I'd love to know Professor Yang's views on this topic?"
Tang Shun picked up the tea and tasted it slowly.
Robert and August blew a few breaths on the cup, and after the tea was cooled, they swallowed it in one gulp, and then stared at the empty cup in a daze, waiting for Xu Zhiliang to add tea.
"This is part of our topic, you can take a look at it first." Yang Ping said that Song Zimo handed the information to Tang Shun.
Tang Shun flipped through the pages one by one: "Two technical routes go at the same time, which requires great human and financial support? Unrealistic. ”
Yang Ping shook his head: "The last thing we need to worry about is money, there is a special foundation to fund our research, and now the funds on the books have exceeded one billion, this is just the beginning, the Anning Group you are familiar with, the Guo family in Southeast Asia, etc., are all our fund providers." ”
Tang Shun was a little shocked, the laboratory of a hospital actually had so much scientific research funds, but he immediately calmed down, Anning Group is an emerging consortium, and Guo's Group has no tradition of funding medical research before, and continuous funding may be a problem.
Tang Shun saw a lot of anticlimactic things, and at first said how much money to provide, but after the first funds were in place, there was no follow-up, either the donors of the funds no longer paid attention to the matter, or the company itself was in financial difficulties or even went bankrupt.
In China, there is a lack of tradition in the funding of scientific research institutions, so it is difficult to have sustainability.
"I'm worried about the durability of the project's funding?" Tang Shun said clearly.
Those who engage in academics are straight men, who come and go straight, save time and improve communication efficiency.
"Understand your concern, what do you think of the Duke's Fund?"
The Duke Fund?
Europe's low-key and secretive aristocratic fund has funded many projects, among which Nobel laureate Mr. Maninstein has received funding from this fund.
Unexpectedly, the Duke's Fund would also provide him with funds, Tang Shun was very surprised.
"A billion euros will arrive soon, and you can talk to Mr. August about the Duke's Fund in detail later." Yang Ping said indifferently.
Tang Shun's heart has begun to make waves, there is one billion yuan in the account, and there are one billion euros to follow, this kind of financial resources can fully support this huge project.
I can't imagine that a hospital laboratory has such a fund-raising capacity.
Tang Shun thought that only the laboratories of the University of Tokyo or the top American universities had this kind of fundraising ability.
"If Dr. Tang is still worried about funding, I can also tell you that in the future, our lab will be backed by the world's largest supporters, and no one can compare." Yang Ping sells a mystery.
"What do you mean?" Tang Shun didn't understand.
"Our country! I don't like to talk about feelings, but today I also talk to Dr. Tang about feelings, if the conditions are equal, I hope Dr. Tang chooses us here, although this is only a hospital-level laboratory, but in the future we can build it into a national laboratory, the world's top laboratory, with our country's economic strength and attention to science and technology, plus our strength, I think it is not difficult. ”
"Our first project --- new technology of external spinal fixator, in cooperation with Union Medical College and Nandu Medical University, the experiment was successfully completed in a few months, and now the phase III clinical trial is being carried out in Europe, the United States and Japan at the same time, it is no exaggeration to say that this is a world-class topic, and in this field, we deservedly lead Europe, the United States and Japan."
When Yang Ping should be proud, he should not be useless and modest.
The new technology of the external spinal fixator, Tang Shun naturally knows, what the Japanese dream of doing, let Yang Ping do it.
Tang Shun has carefully studied Yang Ping's external spinal fixator, which is very technical, and there are many medical and engineering problems to overcome.
The spine orthopedic device cooperated by the Biomechanics Laboratory of the University of Tokyo and the Affiliated Hospital of the University of Tokyo has taken many years and a team of hundreds of people, but there is still no progress.
Presumably, Yang Ping's team will also take a long time, but I was quite surprised when I heard that it had been a few months.
Tang Shun wondered how many teams had taken months to achieve results.
"Professor Yang, the research team of the external spinal fixator, I want to know how many people there are?"
Tang Shun feels that the core team has more than 100 people, and trial and error alone is a huge project, and this kind of topic should be completed by the collaboration of several universities and hospitals.
"In fact, this technology is just our small work, and the core team is just the three of us!"
Yang Ping said slowly.
Tang Shun now set off huge waves in his heart.
External spinal fixator, this world-class technology, there are only three core members?
Only Yang Ping, Song Zimo and Xu Zhiliang?
Tang Shun believed this, because people like Yang Ping don't need to brag, let alone brag to themselves.
Tang Shun has always admired Musk, read his autobiography "Iron Man of Silicon Valley", and still remember Musk's rocket team, dozens of loose guys in slippers actually developed advanced rockets.
Now seeing Yang Ping, I can't help but think of Musk in my heart, and then I have a feeling of admiration.
"Can I take a tour of your lab?" Tang Shun was a little moved.
"Of course, our lab is upstairs, which is very convenient." Yang Ping knew that he was already moved.
Everyone took the elevator to the laboratory, and the stem cell laboratory occupied an entire floor, some graduate students were busy in the laboratory, some were playing table tennis in another recreation room, and some were drinking coffee and reading magazines.
The members of the lab are also dressed very casually, many of them wearing T-shirts and shorts, which is very relaxed.
This kind of scene made Tang Shun feel very familiar again, that is, a photo: behind it is an assembled rocket, a group photo of more than a dozen people wearing T-shirts, jeans and slippers.
This rocket team with the spirit of the Internet in Silicon Valley has the courage to explore, constantly try and make mistakes, and is not afraid of failure, and finally completes the research and development of a new rocket.
"There is a recreation room, you can listen to music, exercise, drink tea or coffee here at any time, no one supervises you, and no one asks you to work, you can arrange your ---own work freely," Yang Ping said, "Yang Ping introduced the way of working in the future.
Tang Shun nodded, he just liked this relaxed and tolerant working atmosphere, and he didn't like the ascetic atmosphere of the University of Tokyo laboratory.
"In terms of equipment, we lack a cryo-EM microscope and need to borrow equipment from Nandu Medical University, but we plan to buy a cryo-EM microscope to save experimental time."
The team moved through the corridor, and Yang Ping introduced the equipment in the laboratory.
It is normal to have a lack of dedicated cryo-EM, and even at the University of Tokyo, cryo-EM is not private to a particular research team, but is used by everyone in turn.
"If you take the route of 3D printing, I don't know where Professor Yang started?"
Tang Shun was already excited, and he had a very good appetite for himself here.
"The two routes are actually very difficult, and the 3D printed route is easier to control, such as stem cells to grow muscles, and the cultivation method may not be able to get the fine structure you want, such as the specified part needs a thicker artery to connect with the recipient area. And 3D printing is easy to achieve this kind of customization, but 3D printing must be in-depth to the anatomy of the target organ to the point of very fine, to complete the real 3D printing, the collection of anatomical data is massive, it is estimated that it takes supercomputing to complete this level of calculation and printing, a muscle nerves, arteriovenous and lymphatic structure, the total length of a circle around the earth is no problem. Lack of fine anatomical data, which is also the reason why 3D printing cannot complete simple cartilage printing, can not replicate fine anatomy, just like an airplane, just make a model, and the internal engine and so on cannot be copied, of course, can not fly into the sky. ”
"The 3D printing route, in the biological stage is much simpler than the cultivation technology, he only needs to cultivate a large number of various living cells, and then use these living cells as raw materials to complete the printing of organs, without the need to crack the various regulation of the human body in the process of organ formation, and the cultivation route of the whole project is larger, from beginning to end at the biological level to complete the construction of organs, the human gene expression and regulation research investment is greater, which is better or worse, it is not yet known, I used to think that cultivation is better, and then I thought that 3D printing is better, and then later, There is no distinction between the two, and the two routes see which one makes a breakthrough first. Yang Ping briefly stated his understanding.
Scientific research is like this, sometimes when there are many routes going together, the first to make a breakthrough will naturally gain an advantage.
Tang Shun agreed with Yang Ping's understanding.
An organ is more complex than you think, which is why a tree can easily produce an apple, while a human cannot replicate one.
The two approaches to solving the problem are different, one figuring out the information contained in the seed and the other figuring out the information contained in the apple.
Tang Shun is a big believer in first principles, which is to reduce things to their very essence.
If stem cells are really to succeed in cultivating muscles, they must start from scratch, and other scientific research results can only be used for reference, and must not be studied on the basis of other achievements.
If you want to print out muscles, you have to do a thorough and complete study of the anatomy of the muscles.
Re-lay the foundation, rebuild the house.
"My lab, in collaboration with Nandu Medical University and Nandu Institute of Technology, borrowed cryo-electron microscopy from Nandu Medical University and Nandu Polytechnic supercomputer, and planned to perform a single-layer cell section of the muscle, and then scan it with an electron microscope to make a fine three-dimensional composition of the entire muscle to obtain a subtle anatomy of the muscle." Yang Ping said this plan.
Performing a slicing scan of a single layer of cells in a muscle is a huge and complex task, and the data is huge.
Tang Shun stopped, it was the first time he had heard of someone doing such a massive amount of work.
The professional division of labor makes everyone "very lazy", always likes to take it, and always uses it directly for things other than the major, and I don't know if this is suitable.
Therefore, engaging in stem cell research will never really study the anatomy of the target organ, and the anatomical will not study the structure of the organ from the perspective of stem cell cultured organs.
Yang Ping wants to start from multiple disciplines and start a new basic research, which coincides with his own ideas.
But can the human and financial resources sustain it?
Thinking about these things again, it is too forward-looking, and it seems that this career has met its first requirement.
And what about the second requirement?
Treatment?
Tang Shun is a person who is very sensitive to money, he doesn't want to engage in scientific research with a meager salary, or worry about life when he doesn't want to do scientific research.
"I'd love to know, how would I be treated if I stayed?"
Tang Shun is very direct.
Yang Ping didn't speak, and no one in the entourage spoke, Tang Shun smiled: "Am I too direct?" ”
"Nope! You are very frank, as for the treatment, I don't think there is any need to talk about it, we are ready, Song Zimo? Yang Ping also smiled.
Song Zimo handed over a document board, on which only a blank piece of paper and a pen were clamped.
A blank piece of paper, what does this mean?
Tang Shun didn't understand.
Yang Ping said lightly: "You write the treatment and all the requirements on this piece of paper, and I will do it!" ”
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