Chapter 878 Trial and Error - The Biggest Cost of Scientific Research
Because there are many injured firefighters, even if they are scattered to various hospitals, Sanbo Hospital has more than 20 firefighters, all of whom are detonation injuries caused by the explosion air waves, and most of the injuries are lungs.
According to the severity of their condition, the more than 20 firefighters were dispersed to the ICU, thoracic surgery, general surgery, orthopedics and other surgical wards.
The firefighters who were admitted to the ICU were all members of Fang Liu's squadron, because they were evacuated from the center of the fire at that time, and the evacuation distance was the farthest, so when the explosion occurred, they were relatively the closest to the explosion, and the explosion wave naturally caused them the greatest damage.
Except for a few firefighters who were admitted to the ICU, the Institute of Surgery was in charge, and the other firefighters were not assigned to the Institute of Surgery for the time being, so Director Fang and Director Gao rushed over and didn't have anything to do, so they went to the ICU to find Yang Ping to see if they could help.
The ICU is very busy now, everyone is very active, actively participating in the diagnosis and treatment of firefighters, Director Gao and Director Fang are not able to intervene, they can only act on the opportunity.
Sure enough, as Yang Ping predicted, three days later, Fang Liu and Lao Xiao were taken out of the ventilator, and other firefighters were also taken out of the ventilator one after another.
Because the nursing work such as sputum suction was done in place, and some antibiotics were used prophylactically, they did not have lung infection, and the lung parenchyma of subsequent damage was slowly repaired, and the exudation of the lungs was slowly absorbed by itself.
Fang Liu and Lao Xiao were transferred to the ward of the Institute of Surgery, and the head nurse led the nurses to hold a small celebration for them, the happiest were Lan Xueping and Wang Xiaojing, who finally saw their living lovers.
Fang Liu was also very surprised to see that Lan Xueping could now stand and walk independently, indicating that the effect of this operation was very good.
According to Zhang Lin's inquiry, none of the firefighters sent to other hospitals had major problems, and they are all recovering.
Fang Liu and Lao Xiao, Zhang Lin and Xiao Wu are the doctors in charge of the bed, one person is in charge of one, Zhang Lin is in charge of Fang Liu, Xiao Wu is in charge of Lao Xiao, Zhang Lin and Xiao Wu are not only the golden hook silver of the Institute of Surgery, but also the senior residents of the Institute of Surgery.
Although they have been promoted to attending doctors, some key patients are still directly managed by them.
Fang Liu became Zhang Lin's patient, how could Zhang Lin let go of this opportunity, every time he made rounds, he conducted a face-to-face interview with Fang Liu, and inquired about the thrilling process of the firefighting scene at that time, this is the real first-hand information, the first-person information obtained directly from Fang Liu's mouth.
Because Fang Liu has been living in the ICU before, even reporters from all walks of life have not interviewed him face-to-face, Zhang Lin can be said to be the first face-to-face interview with the first party Fang Liu, he sorted out the information after getting it, and began to conduct exclusive broadcasts in the hospital, and now the hospital colleagues do not hate him, but like to get news from him, knowing that he really has intelligence sources.
At the beginning, the news from all directions said that the firefighters sacrificed a lot, only Zhang Lin's internal information said that all the firefighters were evacuated safely, and no one died, and later facts proved that Zhang Lin's inside information was very accurate and exciting.
No, Zhang Lin went to the pediatric consultation and was surrounded by pediatric doctors and nurses, so he had to sit down and start to play his strengths.
"At that time, it was thrilling, the line between life and death!"
"After Fang Liu's squadron rescued the people trapped inside, the fire was getting bigger and bigger, and there was a tendency to spread out of control to the surroundings, what was around, it was a factory, a company, and a people, our firefighters were not afraid, they put their life and death aside, and decided to enter the fire center to extinguish the fire, so that the fire could be controlled as soon as possible. Are there any explosives, this director hesitated, and then said loudly, no! ”
''Let me ask you again, are there any explosives?'' Captain Lei Bin saw that the factory director was not confident enough, so he asked loudly again, because he had to figure out what was inside before he dared to let the firefighters in. ”
"It's all everyday processing materials, and there are absolutely no explosives! This time, the director patted his chest and said. ”
In this way, Captain Lei Bin led the firefighters to open the way with water, step by step into the center of the fire source, that is, the warehouse where the fire occurred, and extinguished the fire in the center of the fire source in order to control the fire. I'm sure there's explosives in the warehouse, it's going to explode soon! ”
"When the captain heard the news at this time, his heart was shocked, at this time there were already more than 100 firefighters inside and outside the fire, more than 100 people, the oldest was about to retire, the youngest was only 18 years old, and more than 100 people were inside!"
"Captain Lei Bin got the news, and immediately continued to report while directing the squadrons to evacuate urgently!"
"Everyone! Fall back! Fall back! Unconditional emergency retreat! An explosion is about to happen, so evacuate as far as possible! ”
"Quick! Fast! Fast! ”
"At this time, all the people trapped inside have been safely evacuated, and our firefighters began to retreat as quickly as possible, and the excellent discipline ensures that the order is faithfully carried out by everyone, retreat! Fall back! Fall back! ”
"Captain Lei Bin and Fang Liu are very experienced, they immediately planned the nearest route and quickly evacuated from the center of the fire, at this time the big explosion was already brewing, and even the terrifying sound of Zizi could be heard."
"They were the deepest squadrons, so they took the longest time to evacuate, they evacuated to the northwest, all the way to the outside of the building, and then continued to retreat."
"Still in the process of evacuation, boom! The Big Bang happened. ”
"The earth shakes!"
"Fortunately, all of our firefighters were safely evacuated by this time, but the air wave from the explosion overturned them, many of them fainted, and our people's soldiers arrived and rescued them."
Zhang Lin spoke vividly, as if he was at the scene at the time, and assisted some body movements when he spoke.
Even the director of the pediatric department gathered around to listen to Zhang Lin tell the story of the firefighting at that time, and he listened attentively.
"And then?"
Some people are still unsatisfied.
"Later, Fang Liu and Lao Xiao were sent to the emergency department of our hospital, and our department was also the main force involved in the rescue at that time, and I was the first to rush up——"
Zhang Lin was ready to continue talking.
"Not going back to work yet?"
A female doctor said to Zhang Lin that Zhang Lin looked back and saw that this was not his wife, and immediately got up to say goodbye.
"Don't go, it's not over yet, there's still Fang Liu's heart-wrenching love story-"
"Next time, next -——"
Zhang Lin hurried back in a gloomy manner.
Fang Liu and Lao Xiao Pingsu had good physique and recovered quickly, the detonation injuries in both lungs healed quickly, and the other organ injuries recovered faster because they were very light.
In the ward, Fang Liu has begun to take the map to plan her travel route again, and the improvement of her condition after surgery has also made Lan Xueping have a lot of longing for life, especially the difference between life and death with Fang Liu, she cherishes her current happy life even more, and decides that no matter how the disease develops in the future, she must live a good life and live a wonderful life.
——
Fang Liu and Lao Xiao recovered well, and Yang Ping didn't have to worry about their conditions anymore, he continued his experiments.
Yang Pingxin's project -—— to find the cause of the death of tumor cells has been moving forward.
The results of the electron microscope picture analysis of the dead tumor cells have come out, and the reason for the death of tumor cells is that the apoptosis process is initiated for some unknown reason, causing a chain reaction, resulting in the death of tumor cells as if they had the plague, and this "plague" is like a curse for tumor cells, and none of the remaining tumor cells have escaped the curse and all died.
Apoptosis is an active and orderly suicidal death of cells, which is controlled by genes, and unlike cell necrosis, it is not passive, but active, and often involves the activation, expression and regulation of genes. It is a basic biological phenomenon that plays a very important role in removing unwanted or abnormal cells in multicellular organisms, and it has a very positive effect on living organisms.
For example, if there are mutated cells in the human body, such as tumor cells, the body's immune monitoring mechanism finds that there is a problem with this cell, and immediately starts the apoptosis program, and through a series of gene regulation, finally let the cell actively commit suicide and die, so as to avoid further division and increase the number and cause harm to health.
The total destruction of the tumor cell bank was originally an accident, but Yang Ping was keenly aware that this accident might contain some kind of surprising inside story, so he set up a separate topic for research.
The structure of the dead cells was photographed from the organelle level by electron microscopy, and the cause of death was traced by analyzing a large number of photos, and from the results of the analysis of the data, it can now be determined that the cause of cell death is that the apoptosis program is initiated, and the death process of each cell is completely consistent with the process of apoptosis.
The reason why cancer cells become cancerous is that they escape the body's immune surveillance and ignore the death orders issued by the human body, that is, once the body's surveillance system finds cancerous cells, it will order the cancer cells to start the apoptosis program, that is, to carry out the death program on the cancer cells, but under certain conditions, the cancer cells ignore the body's commands, forcibly block the death program issued by the human body, and continue to divide and grow, so that cancer is formed.
Although it is now known that the death mode of cells is apoptosis, we do not know at which point the escape mechanism of cancer cells fails, and external factors forcibly start the death process, so that these cancer cells successively carry out the death order and commit suicide.
The way of death has been found, but the murderer has not yet been found.
Who is so powerful that it can successfully suppress the escape mechanism of cancer cells, lock them onto the death, and then force them to commit suicide en masse?
Yang Ping thinks about this problem in the laboratory of the system space, grasps this clue and extrapolates backwards, if he can find the cause of apoptosis, maybe he can open up a new way for the treatment of tumors.
The cause of apoptosis may be a substance, or it may be the presence of immaterial energy, information, or other forms.
Next, Yang Ping needs to analyze the electron microscope photos again, this time the content of the analysis is different from the target, the last time is to analyze the photos of the different states of the dead cells, to find out the way and cause of death.
This time, I wanted to find out what happened to the cells before they died, what new factors they were exposed to, or what mutations in genes, or some kind of signal they were influenced by.
This analysis is more complex than the previous state analysis, Yang Ping sorted out the clues, and then decided to use the supercomputer function of the system panel again to analyze what changes have occurred before, during and after death inside and outside the cell, especially the analysis focuses on emerging substances, signals or mutated genes.
Yang Ping postulated that there was such a cause, and he started the second step of the experiment, looking for the K factor, looking for the initiating factor that initiates apoptosis of tumor cells.
After planning all the details of the experiment, Yang Ping handed over the experiment to the system panel and the robotic arm to execute.
As for his main topic, the search for spatially oriented genes, in addition to obtaining spatially oriented genes for muscles, there are no spatially oriented genes for other organs for the time being.
The analysis of genes is a very difficult thing, countless gene points, what is the specific function of each one, this is not a short time to analyze, it needs to do a lot of analysis work repeatedly, and after the analysis results come out, many experiments must be designed to verify whether the analysis results are correct.
These basic scientific research tasks are definitely not easy, otherwise countless scientists and laboratories around the world would not have been working for decades without making critical breakthroughs.
Basic research work involves a lot of data processing and trial and error, and it may be that the research that persists for many years will eventually find that the route is wrong, and the scientific research route needs to be re-planned.
This is the reason why some of the world's top laboratories and companies have established technical barriers that are difficult for latecomers to surpass.
For example, several major pharmaceutical giants in the world have accumulated a large amount of trial and error data in their laboratory databases, and don't underestimate these trial and error data, these are their core and most valuable resources, and these are the biggest technical barriers that they cannot surpass for latecomers.
As a latecomer, what has been poured into a lot of talent, money, and decades of research is likely to have been in someone else's database long ago, and this thing has long been tested by them to be the wrong route.
The most suffocating thing is that no matter how hard the pursuers try, the so-called latest issues are still repeating the trial and error of decades ago.
That's why the world's biggest pharmaceutical giants have never changed hands, relying on this trial-and-error data to firmly occupy the top of the pyramid, leaving there is no hope of catching up with the pursuers.
Yang Ping's system space laboratory makes the biggest cost of scientific research - trial and error very cheap.