Chapter 479: Definitely Domestic
We know that in this world, any drug that wants to be marketed needs to go through many rigorous audits.
Drug safety is a very serious and prudent topic in any country.
Among them, the FDA (American Food and Drug Administration) is the most stringent.
If any innovative drug wants to be marketed in the United States, it needs to submit a new drug application to the FDA and be reviewed and approved by the FDA before it can be marketed.
This includes ingredients, manufacturing processes, clinical trial results, safety assessments, and more.
Every process is very strict and complicated.
However, it is precisely because of such strict regulations that the United States has been able to give birth to a large number of world-famous biopharmaceutical companies such as Pfizer, Johnson & Johnson, Merck, Eli Lilly and so on.
Although the Rockefeller consortium is a diversified and comprehensive consortium based on the oil monopoly, they also have very extensive investments in the fields of medicine and biopharmaceuticals.
It can be traced back to the early 20th century.
Through the Rockefeller Foundation and other organizations, they provide significant financial support for research in the fields of medicine and biopharmaceuticals, and have several prestigious medical research institutions under their umbrella.
Such as: Rockefeller Institute, Baylor College of Medicine, Yale University School of Medicine, San Francisco School of Medicine, etc.
As early as last year, after receiving the sample of the potion sent by Chen Weidong, the Rockefeller Consortium immediately asked its medical research institute to carry out detailed testing and analysis.
They had to pay attention.
Because gene potion is a very rare innovative drug in the current world.
It is also the main direction of medical research institutions around the world.
However, due to the difficulty of research and development, complex technology, and high input costs, only a few companies or research institutions in the world can develop mature gene potions.
These genetic potions can usually only target certain genetic diseases or hereditary diseases.
For most common or complex diseases, there is no effect.
Therefore.
If these two genetic drugs really have the effects described in the report, it will definitely bring them huge business opportunities and profits.
The Rockefeller Institute first used a state-of-the-art gene sequencer to test the genetic sequence of one of the potions to determine the genetic composition and function of the gene potion.
However, during the testing process, they were surprised to find that the biological activity of this gene potion had reached a very terrifying level!
It was more than seventy times higher than the genetic potions they had been exposed to before!
You must know that gene medicine is a pharmaceutical preparation made by mixing gene medicine with solutions such as normal saline.
But it must be biologically active enough to enter the body's cells and interact with the target gene or protein to exert a therapeutic effect.
The higher the biological activity, the stronger the efficacy and better the therapeutic effect of the drug in the organism.
Biological activity is the key factor in the efficacy and therapeutic effect of gene potions.
At present, how to improve the biological activity of gene potions is still a major problem faced by all medical and biological institutions around the world.
This discovery.
It soon alarmed the top biologist at the Rockefeller Institute, Professor Russell Larson.
He is an absolute authority in the field of molecular biology.
In 1953, he discovered the double helix structure of the DNA molecule, which won the Nobel Prize in Medicine, opening the way for mankind to explore the secrets of life and genetics.
The world-famous "Project Jim" is named after his nickname, so he is also known as the "father of DNA" by many people
His intervention made the detection project of this gene potion faster.
With a spectrophotometer, they measured the concentration and purity of the potion.
Under the analysis of the mass spectrometer, they determined the molecular weight and structure of the gene potion, and further confirmed its composition and composition.
Finally, after a month-long observation of the microscopic imaging system and cell culture equipment, Professor Larson finally determined that this potion does have a rapid weight loss effect, which can stimulate the body's metabolic genes and break down excess fat in a short period of time!
The results of the test were quickly sent to John Rockefeller Jr.'s desk.
His eyes kept sparkling with excitement as he flipped through the report.
He understands the importance of this report, which is definitely a leading biotechnology product.
In the field of life sciences, it is of epoch-making significance!
As we all know, the United States is the country with the largest middle class in the world, but it is also the country with the highest number of obese people.
In their eating habits, high-calorie, high-fat, and high-sugar foods account for a large proportion, such as hamburgers, fried chicken, fries, cakes and other fast foods and desserts.
This eating habit can easily lead to a calorie overload, which in turn can lead to obesity.
Especially since 1980, the obesity rate in the United States has soared from 15% to 41.9% in 2008, which means that two-thirds of the United States are overweight.
But what is embarrassing is that with such a high obesity rate, the fitness culture in the United States is very prevalent.
People generally pay great attention to health and believe that physical health is an important guarantee of quality of life.
As a result, they are often willing to spend a lot of time and money on maintaining their health, including investing in fitness.
He has no doubt about the huge market for "diet pills", but his heart is full of contradictions.
At the same time, Professor Larson hurriedly suggested that they needed more genetic potions before they could start clinical trials to get more data to analyze whether the potion had other side effects.
It's just that John Rockefeller Jr.'s next words made him stand on the spot.
"This gene potion was not developed by a biomedical institution in the United States?"
Professor Larson was shocked.
Doesn't this mean that researchers in other countries have made major breakthroughs in the field of gene editing?
With such astonishing news, why was there no news from the scientific community before?
You know, just a few technologies contained in this gene potion are enough for the other party to win several Nobel Prizes!
John Rockefeller Jr. didn't let him dwell on this point for too long, but hoped that he could immediately conduct a comprehensive study of this genetic potion.
Even, try to imitate.
After all, if they can't achieve a dominant advantage, they will be very passive in the next business negotiations.
It's just that Chen Weidong dared to send the samples directly to them, so he naturally had the corresponding confidence.
The research team led by Professor Larson immediately analyzed and studied the chemical composition, gene sequence, biological activity and other aspects of this gene potion.
In the early days, their progress was really fast.
I was also very inspired.
With the help of advanced instruments.
The auxiliary components in the potion, such as protective agents, carriers, buffers, solutions and other small molecule fragments, were all analyzed one by one, and finally integrated into a detailed data of more than 2,000 pages.
But it doesn't stop there.
Because they discovered that the genetic sequence of this potion contains a special gene fragment, which significantly increases the biological activity of the potion, making it exert unimaginable therapeutic effects in the human body.
That's the key.
They then conducted a large number of experiments, but they were unable to increase the biological activity of the potion they developed to the same level as it was by all means.
It's hard to do even a tenth.
This is enough to show that the research progress of the other party in the field of gene editing has far surpassed theirs, and even surpassed the medical institutions in the United States.
Even if many researchers find it difficult to accept, they can only report the results to the consortium truthfully.
And the following day, in the name of the Rockefeller Institute, an application was submitted to the FDA to initiate a clinical trial.
However, since the application process was public, the news quickly caught the attention of domestic pharmaceutical companies in the United States.
And under the hype of the relevant media, the propaganda is known to the whole world.
Those investors who don't know why subconsciously believe that this is proof that America's biotechnology is once again leading the world, so they have bought shares of biopharmaceutical companies such as Pfizer, Roche, and Merck Pharmaceutical.
As a result, the stock prices of listed pharmaceutical companies in the United States ushered in a round of skyrocketing. (End of chapter)