Faced with the stench of the most severely burned right lower limb of the worker Lu Wenjie, the doctors knew that the condition was getting worse just by smelling the smell, and the bacteria were constantly increasing, not to mention that the blood inflammation indicators were flying up again.

If it's confined to the right lower extremity, it's fine, but the bacteria that produce it can enter the bloodstream and then travel all over the body, which is called sepsis, or sepsis.

It is precisely this that burn patients are most afraid of, because they will die.

Chen Qi, Guo Yuanhang, Zhu Huoyan, Luo Yuyang, Sun Chengzhi of the Department of Orthopedics, Shen Zhemin of the Department of General Surgery and other surgeons all looked at the patient's right leg and worried.

Outside the ward, Professor Peng Yongyan, Professor Ni Zhihua, Professor Zhu Lianggong, Professor Wang Qizheng, Professor An Yongchun, and other top domestic experts, accompanied by Lan Lijuan, are also conducting internal medicine consultations.

I have to say that this group of uninvited experts who don't take red envelopes are here, and Lu Wenjie and several other burn patients are really lucky.

However, in order to verify the clinical level of the Vietnamese and Chinese hospitals, and to see if they have any "tricks", the expert group made up their minds to remain neutral, not to express their opinions, and not to point fingers.

Professor Ni Zhihua, in particular, is a little conflicted in his heart, on the one hand, he does not want the patient to die, and on the other hand, he does not want the patient to be cured by the Vietnamese and Chinese hospitals.

Inside the hospital room.

After Shen Zhemin inspected it with gloves, he smacked his lips:

"I think I still have to amputate the leg, you see from here to here, it's all edematous, and necrotic fluid oozing, plus the patient is now having a high fever and confusion, this right lower limb really can't be saved."

As soon as these words came out, the few little doctors behind all nodded in agreement.

The surgeon's thinking is simple, is there a disease? Cut! Cut it clean and then say.

However, as a "famous doctor", Chen Qi obviously does not want to give up a glimmer of hope, after all, theoretically, as long as the inflammation is controlled, the patient's right lower limb can still be saved.

So the question is back to square one, how to control inflammation, or how to kill bacteria.

Zhu Huoyan coughed lightly at this time, attracting everyone's attention:

"Last night, I looked through a lot of literature, and I saw a sterilization program that our country had introduced from the Soviet Union in the fifties and sixties, Guo Shuji, do you remember a kind of bacteriophage called 'bacteriophage', which was also used in our hospital back then."

Bacteriophage?

In the ward, several old doctors all sighed, obviously remembering something.

The young doctors, including Chen Qi, were confused, and the stupidity in their eyes began to become more and more obvious, because they had not learned this medical concept.

"Mr. Zhu, what is a bacteriophage? I, I'm also a person who has read a lot of literature, why haven't I heard of it? ”

Lao Guo laughed when he heard it: "Haha, Chen Qi, there is finally a time when you don't understand, Lao Zhu, teach this kid a lesson!" ”

Outside the ward, Lan Lijuan, Ma Xiaona and others were also confused when they heard "bacteriophage", and then their brains spun quickly, thinking about whether they had studied before.

On the contrary, several professors also smiled.

Professor Peng quipped: "Why, a few of you little comrades don't know about bacteriophages? ”

Lan Lijuan's face turned red, she was still a member of the International Medical Association, the director of the department, and she had never even heard of a medical concept, which was not only her personal face, but also the face of the Vietnamese Hospital.

Unlike Chen Qi, who has a hard mouth, Lan Lijuan is a traditional typical good student, and she humbly asks for advice if she doesn't understand.

"A few professors, I really don't know about this phage, you also know that our primary education is only technical secondary school, and the later undergraduate and graduate students are also sent all the way, and they don't take classes well, so there is a lack of learning, and I hope that a few professors will teach us."

Wang Qi is an old professor of Zhejiang Medical University, and he has the most right to speak:

"Comrade Xiaolan doesn't need to blush, because this bacteriophage is not in undergraduate and graduate teaching textbooks, because this is a treatment plan that has been eliminated."

Professor An Yongchun of Xiangya Hospital also sighed:

"Yes, back then, we were poor in China, we couldn't even produce penicillin, and foreign countries imposed an embargo on us, so a lot of antibiotics couldn't come in, and we relied on smuggling some from the south.

Without medicine, we couldn't cure the sick, especially the soldiers who were traumatized by the war, so then we gave rise to a phage treatment program, which was also a helpless alternative, and then with the increasing number of antimicrobial drugs, phage therapy was also eliminated. ”

In the ward, Zhu Huoyan was also giving Chen Qi a lesson:

"The bacteriophage we are talking about is a general term for a virus that infects microorganisms such as bacteria, fungi, algae, actinomycetes or spirochetes, which can cause lysis of the host bacteria, and the bacteriophage has some characteristics of a virus, and the individual is tiny, does not have a complete cell structure, and only contains a single nucleic acid."

Chen Qi smiled awkwardly: "I didn't understand." ”

Zhu Huoyan has a good temper, and after changing Lao Guo, he is about to scold again, and continues to patiently explain:

"A bacteriophage can be understood as a microorganism that eats bacteria, or a virus, and does not directly infect animals."

Chen Qi was stunned when he heard it, did he?

"Nani? Such a powerful thing, directly eat bacteria, then how come I haven't heard of it? What is the principle of this eating bacteria? ”

Outside the ward, Professor Wang Qizheng was giving Lan Lijuan and them a catch-up lesson

"Traditional antibiotics are bacteriostatic or bactericidal, and the main mechanisms are: inhibiting bacterial cell wall synthesis, enhancing bacterial cell membrane permeability, interfering with bacterial protein synthesis and inhibiting bacterial nucleic acid replication and transcription.

Bacterial phages generally have a narrower host range than antibiotics, and a type of phage generally only has an effect on a specific bacteria, or a specific strain of a bacterium, to help patients attack the bacteria that cause specific diseases.

They use the bacteria's resources to produce progeny phages, and when the bacteria's resources are exhausted, they destroy the entire bacteria, which not only kills the bacteria, but also releases more phages, which they continue to look for the next batch of bacteria that are about to die.

Compared with antibiotics, the benefits of bacteriophages are obvious, antibiotics are less targeted, and tend to indiscriminately kill the probiotic flora in the body, while bacteriophages have a unique effect on the precise elimination of superbugs and are harmless to humans. ”

Lan Lijuan was surprised: "Since the bacteriophage is so easy to use, why was it eliminated later?" ”

Professor Peng chuckled:

"The main thing is that it is unstable, not only the efficacy is unstable, but the source of access is also unstable, and there is definitely no antibiotic that is convenient, fast and effective, so when our country can produce antibacterial drugs by itself, it will be quickly eliminated."

Professor Wang also quipped:

"You think, in the fifties and sixties, those who had money to treat diseases were either rich or expensive, and the common people would definitely not be able to afford injections anyway. It turned out that he would give you a shot of the virus when he treated you, good guy, how could this patient accept it. ”

Hehehe, the atmosphere outside the ward is relaxed.

In the ward, Chen Qi finally understood what a bacteriophage was:

"I understand, that is, now we have to find a Pseudomonas aeruginosa phage, or Staphylococcus aureus phage, and then inject the patient into the body, and then let the phage find the corresponding bacteria to swallow and eat a full meal, isn't this the reason?"

Zhu Huoyan smiled:

"It doesn't have to be injected, in fact, we can make our own phage fluid, and then soak the patient's right lower limb in it, so that the phage can find Pseudomonas aeruginosa on its own, and then eat it, which also plays an anti-infection role."

Chen Qi asked again:

"So how should this bacteriophage be obtained? Is it based on bacterial culture? ”

Lao Guo frowned at this time, as if he thought of something disgusting:

"It's not difficult to find bacteriophages, but the harder this thing is, the dirtier the place, the easier it is to find, like some kind of manure tank, sewer, rotting animal carcasses or something, it's like looking for a needle in a haystack."

At this time, there are many public toilet manure tanks in the city, and most people in the urban area are using toilets or spittoons at home, and there are very few people like the Chen family who build a flush toilet by themselves.

Moreover, the manure in this manure tank is a good thing, and people in the countryside will carry cement boats to carry it away to engage in vegetable planting, and often grab feces and fight for this.

However, in recent years, whether it is a sanitation station or a common people, the awareness of hygiene is not strong, and the public toilets are stinking terribly.

Chen Qi thought that he was going to such a disgusting place to find bacteriophages, and his heart retreated for a while.

"Are you going to the manure tank sewer dump to find bacteriophages?"

Outside the ward, after hearing the professors' explanation, Lan Lijuan looked at her husband inside through the glass.

Knowing the husband and wife, Chen Qi can tolerate the erosive smell caused by corpse odor bacteria, but he can't bear the stench when he defecates.

Therefore, the Chen family is the first person to install a flush toilet on Lu Xun Road, and it is good for others to go to the toilet to poop and flush once, but Chen Qi pulls out one and flushes it once, so the eldest sister often complains about wasting water.

asked Chen Qi to go to the manure tank to find bacteriophages, and Lan Lijuan knew that this guy must be reluctant.

However, the job of finding bacteria can only be done by medical personnel, and ordinary people do not know how to take specimens and how to cultivate bacteriophages.

So Dr. Lan, who aspired to be an infectious disease expert, stood up and shouted into the intercom to Chen Qi inside:

"Chen Qi, why don't you leave the search for bacteriophages to me, and I'll take Yang Yibing and them to find it together?"

Lao Guo and Zhu Huoyan both looked at Chen Qi with disdain......

Chen Qi coughed lightly, knowing that at this time, as the head of the medical team, a young leading cadre, he would definitely take the lead in imitating, not to mention that even a female comrade who was not a burn surgeon was going to be on it, so he was not embarrassed.

But Chen Qi obviously won't let go of the Yue Steel Mill, in order to save their workers, ask him to go to the dean to turn the stool? It's crazy.

"Is Section Chief Zuo here?"

Zuo Liwei, the chief of the medical department, answered outside the ward: "I'm here, Dean Chen." ”

"Lao Zuo, you can arrange for me and Dr. Lan to lead the team in the afternoon, and let the doctors from the laboratory department also come together, and then you will pull out all the interns in our hospital, as well as the 15 students in the endoscopy class.

Half of them went to major public toilets, garbage dumps, and sewers in urban areas to look for bacteriophages, and the other went to open manure pits, muddy floors, and stinky ditches in suburban villages to look for bacteriophages, telling them that they would receive a subsidy of 20 yuan per person.

Oh yes, after the number of people is counted, report to Qi Guomin of the Yue Steel Mill and let him pay for it, grandma, didn't he say that he would do whatever it takes, and we don't need to save him money, if you want to save people, you will obediently give subsidies to students. ”

When Zuo Liwei heard this, he nodded again and again: "Okay, Dean Chen, I will also go with the students in the afternoon." ”

Chen Qi turned his head to look at Lao Guo and Zhu Huoyan, and asked, "What about the two teachers?" ”

Zhu Huoyan didn't look back: "I want to stay with the patient at any time." ”

Lao Guo's eyes looked at the ceiling, "Don't expect me, I'm going to the bureau for a meeting in the afternoon." ”

In the afternoon of the same day, a total of 60 interns, 15 master's students, plus Chen Qi, Lan Lijuan and 13 other teachers, formed 15 6-person fecal search teams.

1 teacher, 5 students in the mode, holding various tools such as dung spoons, buckets, glass bottles, etc., walked out of the gate of Viet Cong Hospital and went in all directions.

There are thousands of bacteria in the feces, such as Escherichia coli, Enterococcus faecium, Aerogenes, Clostridium, Shigella, Vibrio parahaemolyticus, etc.

One bacterium corresponds to one bacteriophage, so there are thousands of phages, and Chen Qi now only needs two kinds of phages: Pseudomonas aeruginosa and Staphylococcus aureus.

Therefore, it is difficult to find this one, and a large number of people are needed to use it, otherwise it will be too late to find it for a few days, and the patient will have to amputate his limb without amputation.

A public toilet in an urban area.

Chen Qi had two cotton balls stuffed in his nose, holding a dung spoon and stirring the feces vigorously, what kind of stool, straw paper, menstrual bands, and even the corpses of dead cats and dogs were flooded, emitting a strong stench.

"Vomit~~Vomit~~~"

Chen Qi retched a few times, and his whole face was swollen and red.

Zhu Jianwei next to him hurriedly patted his ass and said: "Teacher Chen, let me come, I am from the countryside, I am not afraid of dirty." ”

Chen Qi retched while waving his hand: "No, I'm a teacher, I want to lead by example, you quickly take a good sample of this spoonful of fecal water, and record the time and place." ”

Jin Meng is a girl in the city, where has she ever seen this kind of battle, and after the fecal water was picked up, she accidentally knocked over the bottle, and the fecal water spilled on her sneakers.

"Vomit~~Vomit~~~"

She couldn't hold back any longer, jumped away, and then held on to a tree and began to vomit.

Originally, Chen Qi didn't vomit, but when Jin Meng vomited like this, he couldn't help it, and he held on to the other side of the tree, and he vomited a lot.

Vomit~~~

Vomit~~~

Zhu Jianwei and Guan Zelong glanced at each other, their eyes were full of helplessness, and they had to be two rural students at the critical moment.

In the evening, the 15-way fecal search army returned, and the laboratory department started work overnight, and finally found the clinically needed bacteriophage in the standard configuration collected in an open-air fecal pit in Tingshan Township.

That night, President Chen washed it over and over again with imported shower gel......

(End of chapter)