Chapter 650 - Not recognizing the Vietnamese-Chinese formula
Zhu Huoyan was very satisfied with everyone's seriousness, so he continued to speak:
"We at the Vietnamese-Chinese Hospital believe that the Chongqing formula is the most suitable for patients with large-scale burns, while the Shanghai formula is only suitable for patients with small areas and not severe burns, so our Vietnamese-Chinese formula is based on the Chongqing formula and is re-revised according to clinical practice.
The first 24-hour fluid volume for adults = body weight (kg) × burn area (%)× 1.5ml (1.8ml for children), that is, for every 1% of the burn area, 0.75 ml of colloids and crystals per kilogram of body weight, and an additional 2000ml of daily physiological water requirement.
The second 24-hour volume was half of the first 24-hour calculated amount, and the daily volume did not change.
There is one biggest difference between this and the Chongqing formula, that is, we advocate a crystal-glue ratio of 1:1, while the Chongqing formula advocates 2:1.
Moreover, we also advocate early resuscitation with hypertonic saline solution, which can reduce the occurrence of hyponatremia, reduce the content of inflammatory factors in the blood, and reduce edema and oxidative damage in internal organs such as lungs, intestines, liver, and kidneys.
The best effect was achieved at the concentrations of 200, 300 and 400 mmol/L, and at the concentrations of 600, 800 and 1000 mmol/L, and at the concentrations of 600, 800 and 1000 mmol/L.
At the same time, we believe that in patients with large, severe burns, the first thing to do is to replace the colloidal fluid, whole blood, not plasma.
Because we found that early whole blood supplementation was found to be beneficial to correct anemia, improve hypoproteinemia, reduce tissue hypoxia and edema, restore hemodynamic stability, protect internal organs, and improve immune function.
In addition, we found in the study that the tissue residue after the application of colloidal hydroxyethyl starch is heavier, and it may increase the renal impairment and mortality of patients, so we believe that the drug hydroxyethyl starch should be used with caution or not at all.
Finally, we at the Vietnam Hospital believe that traditional shock resuscitation monitoring is not precise enough, and these indicators usually include the patient's mental state, blood pressure, heart rate, extremity temperature, and urine output.
However, these indicators have a significant effect on decompensated shock characterized by hypotension, extreme tachycardia, and oliguria, but are not effective on occult shock with normal blood pressure, heart rate, and urine output, which seriously affects the efficacy of fluid rehydration.
Therefore, we advocate that any burn rehydration should not blindly follow the fluid refusion formula mechanically, but should monitor each index in hemodynamics, and then make up for what is lacking according to each index, so as to improve the hypovolemia caused by burn shock and maintain organ perfusion, and prevent multi-organ failure. ”
As soon as Zhu Huoyan's manuscript paper was finished, the whole array was silent again.
Director Zhu looked up at the participants suspiciously, Chen Qi also blinked, and there was confusion in his eyes, why didn't everyone react?
In fact, what the people of the Vietnamese Hospital didn't know was that everyone was not unresponsive, but was shocked, because the "new formula" of the Vietnamese Hospital can be said to be subversive.
Even the principles and rules came out.
If it weren't for the fact that this was a new formula, what I didn't know would be that I thought it was the "Clinical Rehydration Guidelines for Burns".
Professor Peng already knew about these contents in advance, but the other doctors in the audience didn't know, so they exploded again.
"Director Zhu, how many clinical trials have your formula been underway?"
"Director Zhu, do you have any papers formed?"
Director Zhu ...... Director Zhu ......"
The conference became like a press conference.
After Zhu Huoyan heard this, he gestured to the staff on the side:
"Don't worry, now our staff will send you the principle mechanism, pathophysiology, specific content, experimental data and other information of the Vietnamese-Chinese formula.
He Jia immediately led another staff member and handed over the information in his hand to the participating doctors.
The doctor who got his hands on it couldn't wait to start reading.
In fact, these materials are just a paper, and Chen Qi has already sent it to the New England Medical Journal Nejm one step in advance, and he is not afraid of being cut off by others.
All the data provided in the paper are "fake", but it must be explained that Chen Qi copied the data on the "Surgery", and these data are all conclusions reached by later generations after countless experiments.
As for why it is said to be "fake", it is because Chen Qi himself really did not do relevant experiments.
But the reason why it is true is that these data can stand the test, and it is okay for others to reverse deduce or copy the experiment, and there will be no problem with the data obtained.
This is the advantage of the reborn, just like copying songs and copying in other people's entertainment texts, Chen Qi is copying medical textbooks, and the nature is the same.
Professor Ni Zhihua took the information and put it aside, didn't look at it, just knocked on the table a few times:
"Let's pay attention to the experience summarized by the Vietnamese and Chinese hospitals, how effective is the effect, and whether it is suitable for clinical practice, this still needs time to test, and colleagues in the burn department can refer to it, don't take it too seriously."
The old man is very bad, he wants to downplay the Vietnamese-Chinese formula as a reference rather than the mainstream medical method.
As soon as Professor Ni's words fell, many members close to Dongshan Hospital agreed again and again:
"By the way, I don't know what this Vietnamese-Chinese formula is all about."
"The Vietnamese Hospital is not even a member unit of our Society of Burn Surgery, so it is not good to say what the level is."
"Yes, yes, it's not good, a family's words, refer to it."
Chen Qi, Lao Guo, and President Li all had itchy teeth when they heard this, but they were not members of the Burn Surgery Society, and they only attended this meeting and had no right to speak, so they couldn't stand up and oppose it.
They are "outsiders" and have no qualifications.
But Chen Qi obviously expected this kind of thing to happen, this is not Haidong Medical University, but also someone in the court.
At this time, I saw that Vice Chairman Wang Qizheng took the initiative to stand up:
"If you want to talk about reference, the three major formulas of rehydration we are talking about now are also references, and they are not our original, they are all based on the Evans formula, Brooke formula, Parkland formula, and combined with our clinical summary, so no one should laugh at anyone.
As far as I know, there are 4 burn papers in the Vietnamese and Chinese hospitals this time, all of which have been submitted to top international medical journals, of which 2 have been submitted to the New England Journal of Medicine and 2 to The Lancet.
Therefore, I think that the formula summarized by the Vietnamese and Chinese Hospital in the clinical work of burns is still relatively authoritative, and it is also worthy of everyone's key learning and attention, and may even become another authoritative rehydration formula in China or even internationally. ”
Professor Ni Zhihua impatiently interrupted:
"Lao Wang, there is a problem with your words, everyone can submit papers to major medical journals, even if they are primary school students, but whether people accept them or not, whether they publish them or not is another matter, you can't talk about doing things, if you really want to do it, I will also submit seventy or eighty articles, what's the point?"
Wang Qizheng was not in a hurry, but just gave an example.
"You may not know that for so many years, the Vietnamese Central People's Hospital has submitted a total of 23 papers to the top ten international medical journals, and all 23 papers have been successfully published, and there is no record of failure at present, and the Vietnamese Central People's Hospital is also the hospital that has published the most papers in top medical journals in the country.
What do these 23 top papers represent? As you should all know, I remember that the Union Hospital, which ranks second in the country, has only published 5 papers in top medical journals, and the Vietnamese and Chinese hospitals are far ahead, doesn't this mean that their papers are of high quality and authoritative? ”
As soon as Professor Wang's words fell, the doctors in the audience were shocked to stick out their tongues again and again.
Why?
Because there are so many experts, professors and directors of the Chinese Burn Society, so far, except for Professor Peng Yongyan from Southwest Hospital, who has published a paper in the American Journal of Surgery, no second person has published a paper in top foreign journals.
Domestic burn doctors play the domestic "Chinese Journal of Surgery", and all kinds of connections are used to find contacts, just to publish an article so that they can be promoted.
Not even a single doctor dared to submit his thesis abroad, not even the courage.
Good guy, the Viethorne Hospital sent out 4 papers in one go, is this the rhythm of heaven?
So many doctors with strong curiosity raised their hands to speak again:
"Director Zhu, in addition to the one of the four papers you submitted, in addition to the one rehydration formula, what do the other three involve in burn surgery?"
At this time, Zhu Huoyan signaled to the staff again, asking them to open the "movie player", and the video started on the big screen again.
"Just now everyone has seen the situation of the burn patient before treatment, as well as the procedure of rehydration, and now everyone sees, this worker surnamed Lu has a systemic infection because of serious burns, please pay attention to his right lower limb."
At this time, the camera zoomed in, and Lu Wenjie's gray-black lower right limb appeared on the big screen:
"In particular, the worker's right lower limb has been seriously infected, and we were discussing whether to amputate the limb at that time, but considering that the worker's master will face great difficulties in his work and life in the future, we want to use imported antibacterial drugs for conservative treatment.
As a result, we were surprised to find that this patient was a super resistant king, not sensitive to any antibiotics, on the one hand, severe infection, on the other hand, antimicrobial drugs were ineffective, and the patient had several heartbeats and apnea due to shock, so we finally used bacteriophage therapy, which is the content of the second paper. ”
Bacteriophage therapy?
The people who can come to the meeting are all old experts, and they are all old and there, and they have all heard of or seen phage therapy.
Because they knew, many doctors were slapping the table, looking like they suddenly realized:
"Ah, yes, there's a phage therapy that we all forgot."
"Isn't this a therapy brought to the country by Soviet specialists? How many years have they been eliminated. ”
"I see, I see, this is indeed a strange trick."
Other little doctors may still be ignorant, and they still need the teacher to slowly introduce the principle, but the people present are all top experts, and they can understand it at all.
Many doctors are urging again:
"Director Zhu, what is the effect of your phage therapy? It is said that this bacteriophage was once eliminated because it was unstable. ”
Director Zhu smiled, and said with a smile while continuing to play the video:
"The effect is very good, the patient began to reduce his fever after 24 hours, and now the infection of the whole body is under control, and skin grafting can be done at any time. Although phage therapy is no longer the mainstream treatment option, it is still positive as an alternative.
We judge that in the future, with the development of medicine and the better life of the people, there will be more and more drug-resistant patients, and then phage therapy can save the lives of surgical patients, and it is no longer our doctors who are helpless. ”
At this time, there was applause for the first time in the venue.
If the phage therapy of the Viet-Chinese Hospital is successful, Hua Guo will be the only country in the world to study bacteriophages under the premise that the Soviet Union has already given up on its own initiative.
At this time, the excited doctors asked another question.
"Director Zhu, what is the content of your third paper?"
"For the third paper, let's take a look at the following video."
The movie continued to play on the big screen, and what appeared at this time was Ding Xinjuan's skin grafting surgery process.
When the chief surgeon, Zhu Huoyan, and his assistant Chen Qi used a new skin grafting to solve the problem of patients with large-scale burns, and it was too little normal skin to cover the burned skin of the whole body, the audience was in an uproar.
So they raised their hands one by one and excitedly asked Zhu Huoyan their questions.
"Director Zhu, may I ask if you invented this skin graft?"
"Director Zhu, how many skin implants have you performed, what is the success rate?"
Zhu Huoyan was in a happy mood at this time, grabbed the microphone and said:
"Today, I can responsibly tell you that the new skin graft surgery you see is an original invention of our Vietnamese Traditional Chinese Hospital, and it has been performed on 20 patients so far, with a success rate of 95%, and only one case has failed."
This Zhu Huoyan didn't speak, Chen Qi really did stinky tofu skin grafting for 20 black uncles during the aid to Africa, and the success rate was quite high.
Anyway, black life is like that in the eyes of many people.
Chen Qi is okay, he is saving people, although he is soft when he gets the red envelope.
In fact, many people don't know that Africa is the world's largest "medical experiment base", and all kinds of drugs, procedures, instruments, etc. are experimented on black people.
Even many viral experiments require live human specimens, most of which are carried out in Africa.
Those white people shout that everyone is equal, but behind their backs, they still regard black people as black slaves, and basically do not look at others, just dig a pit and bury them when they die.
For example, the safety of some genetically modified foods requires a large amount of real data, because the cost of experiments in European and American countries is too high, so it is basically eaten by Uncle Black first.
(I don't discuss the good or bad of genetically modified food here, the author saves his life, anyway, please Uncle Black eat it first.) )
"Colleagues, in order to open this annual meeting of burns in Viet Chung Hospital, we have specially reserved skin grafting for three patients, the burn area is 75%, 83%, and 90% respectively, and from tomorrow, we will carry out one every day, and everyone is welcome to watch."
The fact that the Vietnamese and Chinese hospitals let people observe the experiment shows that they are frank, so that many people who doubt it have nothing to say for a while.
After all, no matter how beautiful the PPT is, no matter how good the video is taken, and no matter how much you brag about it, it is not as convincing as you see it with your own eyes.
"May I ask Director Zhu, what is the name of your brand new skin graft surgery?"
When Zhu Huoyan heard this, he suddenly looked constipated, looked at Chen Qi in the corner of the conference room, and then said helplessly:
"In order to reflect the characteristics of Vietnam and China, we officially named it Stinky Tofu Skin Grafting ......"
As soon as the words fell, the conference room fell into a deathly silence again, followed by laughter~~~
It's a pity that three days later, the people at the Viethorne Hospital couldn't laugh.