Chapter 797: The Difficulty of IVF

Many women still have misconceptions about fertility, thinking that they can wait when they are young, and they can have children if they have XX eggs.

So when I was young, I smoked, drank, and had a boyfriend, how crazy I was, and I wanted to have enough of my youth.

As everyone knows, women's fertility varies greatly from each individual, and the aging of egg cells does not match people's biological age, and some women may already have no fertility at the age of 35.

Advanced age not only reduces fertility but also increases the risk of pregnancy.

Although human-assisted implantation technology can help some couples who are unable to conceive a child to have a baby as they wish, the possibility of chromosomal abnormalities in their offspring is very high.

Especially after the age of 40, the probability of chromosomal abnormalities in offspring is more than 1 in 100, which means that one in 100 mothers may give birth to a fetus with chromosomal abnormalities, such as Down syndrome.

That is, the common "sugar baby", the width of the eyes can be known at a glance, and the appearance is the same.

Therefore, women who want to have children should complete the important task of pregnancy in the best reproductive period of 25~29 years old.

Chen Qi nodded to the few little doctors present:

"Trouble, did you listen to it, Yu Shanshan, I heard that you rejected the blind date that everyone introduced to you, this is not good, a woman's career is important, and the family is also important, otherwise you see that Dr. Tao still has to come to do a test tube at such an age, and whether it is successful or not is two words."

Everyone chuckled again.

Yu Shanshan was not afraid of Chen Qi, and retorted:

"Dean, the main thing is that there are more and more patients now, so many that we can't even guarantee a day off, how can you let me fall in love and find a partner, it's all your dean's mistake."

Since Chen Qi became the director, the business growth of the Vietnamese and Chinese hospitals has doubled every year, and the income of the medical staff has increased rapidly, but the workload is indeed very large.

Chen Qi was not angry, and comforted:

"Don't worry, don't worry, haven't I recruited 300 college students this year, and when this group of people comes back from further study, everyone can breathe a sigh of relief, and I will continue to expand my enrollment next year to ensure that everyone will not become medical migrant workers."

Professor Ding interjected with a smile at this time:

"Dean Chen, most of what you said about biomedicine is very novel, not to mention that they haven't heard of it, even I haven't heard of it. So if you don't stop teaching you a lesson. ”

Dean Chen hasn't attended classes for a long time, and his classes used to be all about surgery, and rarely involved internal medicine and gynecology.

But the old staff of the People's Hospital all know that President Chen either doesn't speak, but talks about groundbreaking content, which is very helpful to clinical practice, and every time he gives a lecture in the past, the conference room is full.

"Okay, since you want to listen, I'll talk about it, and the main content of the talk is still for elderly women like Teacher Du Yafang. If the test tubes of these elderly women are good, then the test tubes of young girls will not be a problem at all.

The first thing to talk about is the factors that affect the success of IVF, such as age, uterine environment, embryo quality, etc.

The first is age, as I said earlier, this is one of the most important factors affecting the success rate of IVF.

Because with the increase of age, the female egg nest will gradually age, the function will gradually decline, and the quality of male gold will also decline significantly.

Therefore, the best age for IVF should not exceed 35 years old, otherwise miscarriage or premature birth is easy to occur due to poor physical function.

The second factor is the environment of the sub-XX house,

After the embryo is transferred to the sub-XX uterus, if the sub-XX uterus environment is not good, such as the presence of sub-XX uterine XX endometritis, endometrial polyps, endometrial cancer and other lesions, it will change the environment of the sub-XX uterus, which will easily affect the embryonic development, resulting in the failure of IVF.

The third is embryo quality.

If there is a congenital abnormality in the selected gold or mango, such as an abnormal number of chromosomes or a loss of chromosome structure, it will greatly affect the survival rate of the embryo.

Once the quality of the embryos is poor, it is easy to have embryo termination after the embryo transfer.

In order to improve the success rate of IVF, couples need to carry out systematic and comprehensive preconception screening in advance, especially genetic testing, and remove the unfavorable factors as much as possible before performing IVF, which will help improve the success rate. ”

Yu Shanshan raised her hand at this time and asked:

"Dean Chen, you said that the growth and aging of plants is mainly due to the oval XX and lovary factors, so how do you understand it?"

Chen Qi nodded and drew an anatomical diagram on the paper:

"The nest of eggs is like a woman's planting bank, and the wealth reserve of the nest can be divided into two parts: the original pool (the resting base of the egg XX pool) and the dynamic pool (the growing egg XX pool).

This is like a deposit in the bank and the cash circulating in hand, the primordial egg XX vesicle in the original state pool is activated and becomes a growing egg XX vesicle into the dynamic pool, and only one egg XX vesicle can be expelled after being selected by superiority in the monthly XX menstrual cycle.

From birth, there are about 1 million to 2 million basal oval vesicles, and as the only form of ovarian XX vesicle reserves, it naturally declines and dies every day.

After the age of 35, the reserve capacity of the ovaries decreases, and the number of inferior egg XX follicles also increases.

After the age of 40, the oval XX vesicle is accelerated and the phenomenon of "folding sticks" appears, just like a steep slope that suddenly appears on the downhill road.

So what is the mechanism that regulates fertility? Speaking of which, let's remember, Professor Ding, Director Xu, and a few others must pay attention to this key knowledge, what are the factors that regulate the ability to grow and plant?

This is still controversial and still being studied, and you can set up a research group, which is another international paper.

Let me start by reminding you that the hypothalamic-pituitary-ovary-nest axis regulates the process of female reproductive aging through classical feedback pathways, which is a recent study by Mayo that I know of.

I hope you can use this case of Teacher Du Yafang to demonstrate this scientific research in advance, and intercept Hu Meio, then you can count your ability. ”

"Wow, Dean Chen, you traitor is so good~~~"

The doctors at the plant center applauded warmly, because Dean Chen had given them another big gift.

In the past, working in their respective departments, this group of doctors had little access to good topics, and it was even more difficult to write a thesis.

But when I arrived at the plant center, I felt that I couldn't finish the paper, and I couldn't finish it at all, and it turned out that there were too many topics and there was a kind of happy trouble.

Only Chen Qi knows in his heart that this theory of "hypothalamic-pituitary-oval XX nest axis" has not been published by relevant experts until 2004, and it is still blank.

Therefore, following a leader like Chen Qi is too happy to be a subordinate.

After some careful examination, on the third day, the Biobot Medical Center had found out that the main problem of Dr. Tao Peiliang and Mr. Du Yafang was the woman.

Although the man's tadpole is not vigorous enough, it is more than enough to give birth.

In addition to bilateral L-tube obstruction, Mr. Du also found that there were sub-XX endometriosis lesions and pelvic adhesions in the pelvis.

Not only is there a disease, but the AMH value of Mr. Du's egg XX nest reserve function is only 0.68ng/ml, which means that it is difficult for the key "mangs" to mature and be discharged normally.

But this is the key to IVF, you have to have a healthy, sufficient number of "mountains" to do it.

Director Xu Anqin felt very uncomfortable after getting this report, and she could feel how eager her old colleague was to have a child of her own.

And what happened to the Tao family is a major gossip, in fact, it quickly spread to the hospital, which is actually quite infuriating.

Tao Peiliang is also a doctor, he can understand the results, and after getting the checklist, he also sighed:

"Alas, it seems that it's fate, when my lover and I mustered up the courage to do IVF, but God won't give us a chance."

Professor Ding sat there pondering and suddenly thought of a treatment she had been exposed to when she was a visiting scholar in Hong Kong:

"No, in fact, it's not impossible, there is a new drug abroad that can be aimed at ovulation induction."

"What medicine?" Everyone asked in unison.

"Chorionic gonadotropin needles for injection!"

"Chorionic gonadotropin injections? I haven't heard of it, which pharmaceutical factory in China produces it? ”

Faced with doubtful colleagues, Professor Ding quickly explained:

"This drug is not currently available in China, and it is also recently developed in the United States, and it is made of chorionic gonadotropin extracted from the urine of pregnant women or the XX product of artificial abortion."

Many doctors were a little surprised: "Wow, extracted from urine? This, this is too disgusting, isn't it the same as the 'human yellow' of traditional Chinese medicine. ”

"Then you are wrong, this medicine is very versatile, and the effect is also very obvious,

For example, it can be used for the treatment of prepubertal hypotensis, male infertility caused by hypopituitarism, female infertility without XX ovulation, XX sperm outside the body, luteal insufficiency, functional XX uterine hemorrhage, early pregnancy threatened miscarriage, habitual miscarriage XX and so on. ”

"Wow, that's amazing......"

In 1990, there was almost no domestic drug for gynecology, or infertility, and almost all of them were in the world of traditional Chinese medicine.

In addition, in this era, the country is carrying out very strict family planning, thinking about how to have fewer children and how to encourage childbirth?

China's emphasis on plant medicine has not been started until after 2005, and it has not entered the fast lane until 2010.

No matter how the media bragged later, in fact, our country is far behind in the area of biochemical medicine, such as the genetics in it, alas, I can't say more, and if I say too much, I will say that the author is providing negative energy.

Of course, advertising is always far ahead, and those telephone poles and street corners are full of infertility small advertisements......

Therefore, in the eighties and nineties, domestic doctors could not have access to the world's advanced drugs, advanced treatment methods and equipment, and they lacked too much cognition.

This is also the purpose of Chen Qi's insistence on asking a few professors from Haidong Medical University.

Compared with the local school, the foreign school is much worse in terms of clinical technology and vision.

(End of chapter)